Search Results - "Zou, Guozhang"

In-Depth Compositional and Structural Characterization of N‑Glycans Derived from Human Urinary Exosomes by Song, Woran, Zhou, Xiaomei, Benktander, John D, Gaunitz, Stefan, Zou, Guozhang, Wang, Ziyu, Novotny, Milos V, Jacobson, Stephen C

“…The study of exosomes has become increasingly popular due to their potentially important biological roles. Urine can be used as an effective source of exosomes…”
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Comprehensive Analytical Approach toward Glycomic Characterization and Profiling in Urinary Exosomes by Zou, Guozhang, Benktander, John D, Gizaw, Solomon T, Gaunitz, Stefan, Novotny, Milos V

“…Exosomes are extracellular nanosized vesicles with lipid bilayers encapsulating nucleic acids and proteins, both with and without glycosylation. While exosomal…”
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Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX by Pazgier, Marzena, Liu, Min, Zou, Guozhang, Yuan, Weirong, Li, Changqing, Li, Chong, Li, Jing, Monbo, Juahdi, Zella, Davide, Tarasov, Sergey G, Lu, Wuyuan

“…The oncoproteins MDM2 and MDMX negatively regulate the activity and stability of the tumor suppressor protein p53--a cellular process initiated by MDM2 and/or…”
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Cell Membrane Tracker Based on Restriction of Intramolecular Rotation by Zhang, Chunqiu, Jin, Shubin, Yang, Keni, Xue, Xiangdong, Li, Zhipeng, Jiang, Yonggang, Chen, Wei-Qiang, Dai, Luru, Zou, Guozhang, Liang, Xing-Jie

“…The fluorescence of tetraphenylethylene (TPE), an archetypal luminogen, is induced by restriction of intramolecular rotation (RIR). TPE was grafted with…”
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A smart pH-switchable luminescent hydrogel by Zhang, Chunqiu, Li, Yiwei, Xue, Xiangdong, Chu, Pengfei, Liu, Chang, Yang, Keni, Jiang, Yonggang, Chen, Wei-Qiang, Zou, Guozhang, Liang, Xing-Jie

“…Here we report a novel example of a luminescent hydrogel, which is formed from silent individual molecules simply by altering the pH of the system. Formation…”
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Mosaic quadrivalent influenza vaccine single nanoparticle characterization by Yang, Rong Sylvie, Traver, Maria, Barefoot, Nathan, Stephens, Tyler, Alabanza, Casper, Manzella-Lapeira, Javier, Zou, Guozhang, Wolff, Jeremy, Li, Yile, Resto, Melissa, Shadrick, William, Yang, Yanhong, Ivleva, Vera B., Tsybovsky, Yaroslav, Carlton, Kevin, Brzostowski, Joseph, Gall, Jason G., Lei, Q. Paula

“…Recent work by our laboratory and others indicates that co-display of multiple antigens on protein-based nanoparticles may be key to induce cross-reactive…”
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Multicellular Tumor Spheroids as an in Vivo–Like Tumor Model for Three-Dimensional Imaging of Chemotherapeutic and Nano Material Cellular Penetration by Ma, Hui-li, Jiang, Qiao, Han, Siyuan, Wu, Yan, Tomshine, Jin Cui, Wang, Dongliang, Gan, Yaling, Zou, Guozhang, Liang, Xing-Jie

“…We present a flexible and highly reproducible method using three-dimensional (3D) multicellular tumor spheroids to quantify chemotherapeutic and nanoparticle…”
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Single-Walled Carbon Nanotubes Alter Cytochrome c Electron Transfer and Modulate Mitochondrial Function by Ma, Xiaowei, Zhang, Li-Hua, Wang, Li-Rong, Xue, Xue, Sun, Ji-Hong, Wu, Yan, Zou, Guozhang, Wu, Xia, Wang, Paul C, Wamer, Wayne G, Yin, Jun-Jie, Zheng, Kaiyuan, Liang, Xing-Jie

“…Single-walled carbon nanotubes (SWCNTs) are broadly used for various biomedical applications such as drug delivery, in vivo imaging, and cancer photothermal…”
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Through the Looking Glass, Mechanistic Insights from Enantiomeric Human Defensins by Wei, Gang, de Leeuw, Erik, Pazgier, Marzena, Yuan, Weirong, Zou, Guozhang, Wang, Jianfeng, Ericksen, Bryan, Lu, Wei-Yue, Lehrer, Robert I., Lu, Wuyuan

“…Despite the small size and conserved tertiary structure of defensins, little is known at a molecular level about the basis of their functional versatility. For…”
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Limitations of Peptide Retro-inverso Isomerization in Molecular Mimicry by Li, Chong, Pazgier, Marzena, Li, Jing, Li, Changqing, Liu, Min, Zou, Guozhang, Li, Zhenyu, Chen, Jiandong, Tarasov, Sergey G., Lu, Wei-Yue, Lu, Wuyuan

“…A retro-inverso peptide is made up of d-amino acids in a reversed sequence and, when extended, assumes a side chain topology similar to that of its parent…”
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Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37 by Pazgier, Marzena, Ericksen, Bryan, Ling, Minhua, Toth, Eric, Shi, Jishu, Li, Xiangdong, Galliher-Beckley, Amy, Lan, Liqiong, Zou, Guozhang, Zhan, Changyou, Yuan, Weirong, Pozharski, Edwin, Lu, Wuyuan

“…Cathelicidins form a family of small host defense peptides distinct from another class of cationic antimicrobial peptides, the defensins. They are expressed as…”
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An etanercept O-glycovariant with enhanced potency by Biel, Thomas G., Faison, Talia, Matthews, Alicia M., Zou, Guozhang, Ortega-Rodriguez, Uriel, Pegues, Melissa A., Azer, Nicole, Gomez, Fabiola, Johnson, Sarah, Rogstad, Sarah, Chen, Kang, Xie, Hang, Agarabi, Cyrus, Rao, V. Ashutosh, Ju, Tongzhong

“…Most therapeutic proteins are glycosylated with N-glycans and/or O-glycans. N-glycans on therapeutic proteins have been extensively studied for their control…”
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Defining the Native Disulfide Topology in the Somatomedin B Domain of Human Vitronectin by Li, Xiangqun, Zou, Guozhang, Yuan, Weirong, Lu, Wuyuan

“…The N-terminal 44 amino acid residues of the human plasma glycoprotein vitronectin, known as the somatomedin B (SMB) domain, mediates the interaction between…”
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DNA Origami as a Carrier for Circumvention of Drug Resistance by Jiang, Qiao, Song, Chen, Nangreave, Jeanette, Liu, Xiaowei, Lin, Lin, Qiu, Dengli, Wang, Zhen-Gang, Zou, Guozhang, Liang, Xingjie, Yan, Hao, Ding, Baoquan

“…Although a multitude of promising anti-cancer drugs have been developed over the past 50 years, effective delivery of the drugs to diseased cells remains a…”
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Self-Assembled Peptide Nanofibers Designed as Biological Enzymes for Catalyzing Ester Hydrolysis by Zhang, Chunqiu, Xue, Xiangdong, Luo, Quan, Li, Yiwei, Yang, Keni, Zhuang, Xiaoxi, Jiang, Yonggang, Zhang, Jinchao, Liu, Junqiu, Zou, Guozhang, Liang, Xing-Jie

“…The structural arrangement of amino acid residues in a native enzyme provides a blueprint for the design of artificial enzymes. One challenge of mimicking the…”
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Enhanced siRNA Delivery and Silencing Gold–Chitosan Nanosystem with Surface Charge-Reversal Polymer Assembly and Good Biocompatibility by Han, Lu, Zhao, Jing, Zhang, Xu, Cao, Weipeng, Hu, Xixue, Zou, Guozhang, Duan, Xianglin, Liang, Xing-Jie

“…A simple nanocarrier coated with chitosan and the pH-responsive charge-reversible polymer, PAH-Cit, was constructed using layer-by-layer assembly to deliver…”
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Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment by Kumar, Anil, Ma, Huili, Zhang, Xu, Huang, Keyang, Jin, Shubin, Liu, Juan, Wei, Tuo, Cao, Weipeng, Zou, Guozhang, Liang, Xing-Jie

“…Abstract Functionalization of nanostructures such as gold nanoparticles ( Au NPs) with different biological molecules has many applications in biomedical…”
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Probe-Inspired Nano-Prodrug with Dual-Color Fluorogenic Property Reveals Spatiotemporal Drug Release in Living Cells by Xue, Xiangdong, Jin, Shubin, Zhang, Chunqiu, Yang, Keni, Huo, Shuaidong, Chen, Fei, Zou, Guozhang, Liang, Xing-Jie

“…The versatility of the fluorescent probes inspires us to design fluorescently traceable prodrugs, which enables tracking the drug delivery kinetics in living…”
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Chemoenzymatic Synthesis and Fcγ Receptor Binding of Homogeneous Glycoforms of Antibody Fc Domain. Presence of a Bisecting Sugar Moiety Enhances the Affinity of Fc to FcγIIIa Receptor by Zou, Guozhang, Ochiai, Hirofumi, Huang, Wei, Yang, Qiang, Li, Cishan, Wang, Lai-Xi

“…Structurally well-defined IgG-Fc glycoforms are highly demanded for understanding the effects of glycosylation on an antibody’s effector functions. We report…”
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Imaging Intracellular Anticancer Drug Delivery by Self-Assembly Micelles with Aggregation-Induced Emission (AIE Micelles) by Zhang, Chunqiu, Jin, Shubin, Li, Shengliang, Xue, Xiangdong, Liu, Juan, Huang, Yuran, Jiang, Yonggang, Chen, Wei-Qiang, Zou, Guozhang, Liang, Xing-Jie

“…Nanoformulations show many therapeutic advantages over conventional formulations. We seek to develop traceable nanoformulations in order to closely monitor…”
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