Search Results - "Zorzi, Giovanni"

Box Behnken design of siRNA-loaded liposomes for the treatment of a murine model of ocular keratitis caused by Acanthamoeba by Zorzi, Giovanni K., Schuh, Roselena S., Maschio, Vinicius J., Brazil, Nathalya T., Rott, Marilise B., Teixeira, Helder F.

“…[Display omitted] •A liposomal vector was proposed and optimized by Box Behnken design tool.•siRNA was efficiently complexed with liposome at +5/−1 charge…”
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Nanoparticles based on naturally-occurring biopolymers as versatile delivery platforms for delicate bioactive molecules: An application for ocular gene silencing by Parraga, Jenny E., Zorzi, Giovanni K., Diebold, Yolanda, Seijo, Begoña, Sanchez, Alejandro

“…[Display omitted] Nanoparticles based on naturally-occurring biopolymers, most of them endogenous macromolecules, were designed as a versatile generation of…”
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siRNA‐loaded liposomes: Inhibition of encystment of Acanthamoeba and toxicity on the eye surface by Faber, Kathrin, Zorzi, Giovanni K., Brazil, Nathalya T., Rott, Marilise B., Teixeira, Helder F.

“…Current treatments for Acanthamoeba keratitis are unspecific. Because of the presence of the resilient cyst form of the parasite, the infection is persistent…”
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Hybrid Nanoparticle Design Based on Cationized Gelatin and the Polyanions Dextran Sulfate and Chondroitin Sulfate for Ocular Gene Therapy by Zorzi, Giovanni Konat, Párraga, Jenny Evelin, Seijo, Begoña, Sánchez, Alejandro

“…We describe the development of hybrid nanoparticles composed of cationized gelatin and the polyanions CS and DS for gene therapy in the ocular surface. The…”
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Quercetin and 3‐O‐methylquercetin in vitro skin layers permeation/retention from hydrogels: why only a methoxy group difference determines different behaviors? by Schwingel, Liege C., Bianchi, Sara E., Zorzi, Giovanni K., Gonçalves, Paulo, Teixeira, Helder F., Bassani, Valquiria L.

“…Objectives The present study was designed to verify if quercetin (QCT), a flavonoid with antioxidant and antiviral activity, and 3‐O‐methylquercetin (3OMQ), a…”
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Comparison of different cationized proteins as biomaterials for nanoparticle-based ocular gene delivery by Zorzi, Giovanni K., Párraga, Jenny E., Seijo, Begoña, Sanchez, Alejandro

“…[Display omitted] •Cationized proteins were used for nanoparticulate ocular gene delivery.•Albumin, gelatin and atelocollagen were cationized with spermine or…”
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‘Progetto Sum’: per la presenza sociale e la cura con il soggetto by Buffagni, Federico, Durante, Francesca, Mistrali, Maurizio, Polito, Laura, Santi, Sara, Vanni, Fabio, Zorzi, Giovanni

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Structural analysis of nanosystems: Solid Sorbitan esters Nanoparticles (SSN) as a case study by Pensado, Andrea, Martín-Pastor, Manuel, Zorzi, Giovanni K., Carvalho, Edison S., Sanchez, Alejandro

“…[Display omitted] Innovative approaches in nanotechnology can provide drug delivery systems with a high potential in different fields. To avoid trial and error…”
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On the use of nanotechnology-based strategies for association of complex matrices from plant extracts by Zorzi, Giovanni Konat, Carvalho, Edison Luis Santana, von Poser, Gilsane Lino, Teixeira, Helder Ferreira

“…Depending on the method of extraction, plant extracts can contain an enormous variety of active molecules, such as phenolic compounds, essential oils,…”
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Chemically modified gelatin as biomaterial in the design of new nanomedicines by Lopez-Cebral, Rita, Martín-Pastor, M, Parraga, Jenny Evelin, Zorzi, Giovanni Konat, Seijo, Begoña, Sanchez, Alejandro

“…The synthesis of new polymers has led to dramatic enhancements in the medical field. In particular, new chemical entities provided new prospects in tissue…”
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La fattoria dei nostri sogni: di John Chester, 2018 - FARMLORE FILMS by Zorzi, Giovanni

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La fattoria dei nostri sogni by Giovanni Zorzi

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A chemically-induced acute model of maple syrup urine disease in rats for neurochemical studies by Bridi, Raquel, Fontella, Fernanda U., Pulrolnik, Vânia, Braun, César A., Zorzi, Giovanni K., Coelho, Daniella, Wajner, Moacir, Vargas, Carmen Regla, Dutra-Filho, Carlos Severo

“…We report a chemically-induced model of maple syrup urine disease (MSUD) in 10- and 30-day-old rats produced by subcutaneous administration of a branched-chain…”
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Captain Fantastic: Matt Ross, USA, 2016 by Zorzi, Giovanni

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Captain Fantastic by Giovanni Zorzi

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Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats by Bridi, Raquel, Latini, Alexandra, Braum, Cesar A, Zorzi, Giovanni K, Moacir, Wajner, Lissi, Eduardo, Dutra-Filho, Carlos Severo

“…Maple syrup urine disease (MSUD) is a metabolic disorder caused by the deficiency of the activity of the mitochondrial enzyme complex branched-chain L-2-keto…”
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α-keto acids accumulating in maple syrup urine disease stimulate lipid peroxidation and reduce antioxidant defences in cerebral cortex from young rats by BRIDI, Raquel, BRAUN, César A, ZORZI, Giovanni K, WANNMACHER, Clovis M. D, WAJNER, Moacir, LISSI, Eduardo G, DUTRA-FILHO, Carlos Severo

“…Maple syrup urine disease (MSUD) is an inherited neurometabolic disorder caused by deficiency of branched-chain alpha-keto acid dehydrogenase complex activity…”
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5-Oxoproline reduces non-enzymatic antioxidant defenses in vitro in rat brain by Pederzolli, Carolina D, Sgaravatti, Angela M, Braum, César A, Prestes, Cristina C, Zorzi, Giovanni K, Sgarbi, Mirian B, Wyse, Angela T S, Wannmacher, Clóvis M D, Wajner, Moacir, Dutra-Filho, Carlos S

“…5-Oxoproline (pyroglutamic acid) accumulates in glutathione synthetase deficiency, an inborn metabolic defect of the gamma-glutamyl cycle. This disorder is…”
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The functional role of cerebellum in visual hallucinations by Zorzi, Giovanni, Cecchin, Diego, Poggiali, Davide, Corbetta, Maurizio, Cagnin, Annachiara

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The role of cerebellum in visual hallucinations: A metabolic point of view. A commentary on Lawn and ffytche (2021) by Zorzi, Giovanni, Poggiali, Davide, Cecchin, Diego, Cagnin, Annachiara

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