Search Results - "Zorzan, Eleonora"

Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule by Zorzan, Eleonora, Elgendy, Ramy, Giantin, Mery, Dacasto, Mauro, Sissi, Claudia

“…G-quadruplexes (G4) are secondary nucleic acid structures that have been associated with genomic instability and cancer progression. When present in the…”
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G-Quadruplex Modulation of SP1 Functional Binding Sites at the KIT Proximal Promoter by Da Ros, Silvia, Nicoletto, Giulia, Rigo, Riccardo, Ceschi, Silvia, Zorzan, Eleonora, Dacasto, Mauro, Giantin, Mery, Sissi, Claudia

“…The regulation of conformational arrangements of gene promoters is a physiological mechanism that has been associated with the fine control of gene expression…”
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Mutational Hotspot of TET2, IDH1, IDH2, SRSF2, SF3B1, KRAS, and NRAS from Human Systemic Mastocytosis Are Not Conserved in Canine Mast Cell Tumors by Zorzan, Eleonora, Hanssens, Katia, Giantin, Mery, Dacasto, Mauro, Dubreuil, Patrice

“…Both canine cutaneous mast cell tumor (MCT) and human systemic mastocytosis (SM) are characterized by abnormal proliferation and accumulation of mast cells in…”
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Hypermethylation-Mediated Silencing of CIDEA , MAL and PCDH17 Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies by Zorzan, Eleonora, Elgendy, Ramy, Guerra, Giorgia, Da Ros, Silvia, Gelain, Maria Elena, Bonsembiante, Federico, Garaffo, Giulia, Vitale, Nicoletta, Piva, Roberto, Marconato, Laura, Aresu, Luca, Dacasto, Mauro, Giantin, Mery

“…Gene expression is controlled by epigenetic deregulation, a hallmark of cancer. The DNA methylome of canine diffuse large B-cell lymphoma (cDLBCL), the most…”
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Validation of epigenetic mechanisms regulating gene expression in canine B-cell lymphoma: An in vitro and in vivo approach by Da Ros, Silvia, Aresu, Luca, Ferraresso, Serena, Zorzan, Eleonora, Gaudio, Eugenio, Bertoni, Francesco, Dacasto, Mauro, Giantin, Mery

“…Despite canine B-cell Lymphoma (BCL) representing the most common haematological tumour, epigenetic events driving development and progression are scarcely…”
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Sequencing and G-quadruplex folding of the canine proto-oncogene KIT promoter region: might dog be used as a model for human disease? by Da Ros, Silvia, Zorzan, Eleonora, Giantin, Mery, Zorro Shahidian, Lara, Palumbo, Manlio, Dacasto, Mauro, Sissi, Claudia

“…Downregulation of gene expression by induction of non-canonical DNA structures at promotorial level is a novel attractive anticancer strategy. In human, two…”
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Significance of the goby Zosterisessor ophiocephalus as a sentinel species for Venice Lagoon contamination: Combining biomarker responses and bioaccumulation by Pauletto, Marianna, Lopparelli, Rosa M., Pegolo, Sara, Armani, Mariachiara, Zorzan, Eleonora, Giantin, Mery, Bertotto, Daniela, Gallocchio, Federica, Zancanella, Vanessa, Capolongo, Francesca, Binato, Giovanni, Mutinelli, Franco, Dacasto, Mauro

“…The Venice Lagoon is an interesting example of an ecosystem suffering for a considerable anthropogenic impact, resulting in high concentrations of persistent…”
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Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models by Zorzan, Eleonora, Da Ros, Silvia, Musetti, Caterina, Shahidian, Lara Zorro, Coelho, Nuno Filipe Ramos, Bonsembiante, Federico, Létard, Sébastien, Gelain, Maria Elena, Palumbo, Manlio, Dubreuil, Patrice, Giantin, Mery, Sissi, Claudia, Dacasto, Mauro

“…Stabilization of G-quadruplex (G4) structures in promoters is a novel promising strategy to regulate gene expression at transcriptional and translational…”
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Abstract 4551: Impairment of c-kit expression in human cancer cell lines by a novel pharmacophoric unit selected for the recognition of the proto-oncogene KIT promotorial region by Sissi, Claudia, Da Ros, Silvia, Zorzan, Eleonora, Musetti, Caterina, Shahidian, Lara Zorro, Palumbo, Manlio, Giantin, Mery, Dacasto, Mauro

“…G-quadruplex structures at telomeric region and in oncogene promotorial sequences represent promising chemotherapeutic targets. Among these latter ones, an…”
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DNA and RNA isolation from canine oncologic formalin-fixed, paraffin-embedded tissues for downstream “-omic” analyses: possible or not? by Granato, Anna, Giantin, Mery, Ariani, Pietro, Carminato, Antonio, Baratto, Chiara, Zorzan, Eleonora, Vascellari, Marta, Bozzato, Elisa, Dacasto, Mauro, Mutinelli, Franco

“…Formalin-fixed, paraffin-embedded (FFPE) tissues represent a unique source of archived biological material, but obtaining suitable DNA and RNA for…”
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Mutational Hotspot of TET2, IDH1, IDH2, SRSF2, SF3B1, KRAS, and NRAS from Human Systemic Mastocytosis Are Not Conserved in Canine Mast Cell Tumors: e0142450 by Zorzan, Eleonora, Hanssens, Katia, Giantin, Mery, Dacasto, Mauro, Dubreuil, Patrice

“…Introduction Both canine cutaneous mast cell tumor (MCT) and human systemic mastocytosis (SM) are characterized by abnormal proliferation and accumulation of…”
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Sequencing and G-Quadruplex Folding of the Canine Proto-Oncogene KIT Promoter Region: Might Dog Be Used as a Model for Human Disease?: e103876 by Ros, Silvia Da, Zorzan, Eleonora, Giantin, Mery, Shahidian, Lara Zorro, Palumbo, Manlio, Dacasto, Mauro, Sissi, Claudia

“…Downregulation of gene expression by induction of non-canonical DNA structures at promotorial level is a novel attractive anticancer strategy. In human, two…”
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