Search Results - "Zorrilla, Leah M"
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The Effects of Triclosan on Puberty and Thyroid Hormones in Male Wistar Rats
Published in Toxicological sciences (01-01-2009)“…Triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) is a potent antibacterial and antifungal compound that is widely used in personal care products, plastics,…”
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The effects of simazine, a chlorotriazine herbicide, on pubertal development in the female Wistar rat
Published in Reproductive toxicology (Elmsford, N.Y.) (01-07-2010)“…Chlorotriazine herbicides, such as atrazine and its metabolites, have been shown to target the neuroendocrine regulation of male and female reproductive…”
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3
Understanding the effects of atrazine on steroidogenesis in rat granulosa and H295R adrenal cortical carcinoma cells
Published in Reproductive toxicology (Elmsford, N.Y.) (01-02-2011)“…Atrazine (2-chloro-4-ethylamino-6-isopropylamino-s-triazine) was introduced in the 1950s as a broad spectrum herbicide, and remains one of the most widely used…”
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The effects of prenatal exposure to atrazine on pubertal and postnatal reproductive indices in the female rat
Published in Reproductive toxicology (Elmsford, N.Y.) (01-07-2011)“…Atrazine (ATR) is an herbicide that exerts negative reproductive effects. We examined the effects of vehicle or ATR (1, 5, 20 and 100 mg/kg-d), administered to…”
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Triclosan Exposure Modulates Estrogen-Dependent Responses in the Female Wistar Rat
Published in Toxicological sciences (01-09-2010)“…Triclosan is an antimicrobial found in personal care and sanitizing products, such as soaps, toothpaste, and hair products. There have been recent concerns for…”
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Distinguishing between endocrine disruption and non-specific effects on endocrine systems
Published in Regulatory toxicology and pharmacology (01-11-2018)“…The endocrine system is responsible for growth, development, maintaining homeostasis and for the control of many physiological processes. Due to the integral…”
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Practical considerations for developmental thyroid toxicity assessments: What's working, what's not, and how can we do better?
Published in Regulatory toxicology and pharmacology (01-08-2019)“…Thyroid hormones (THs; T3 and T4) play a role in development of cardiovascular, reproductive, immune and nervous systems. Thus, interpretation of TH changes…”
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Analysis of EPA’s endocrine screening battery and recommendations for further review
Published in Regulatory toxicology and pharmacology (01-08-2015)“…•EPA screens chemicals for the potential to interact with the endocrine system.•Analyses reveal that many of the screening assays have poorly-defined…”
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A single gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts the adult uterine response to estradiol in mice
Published in Toxicological sciences (01-12-2013)“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) given as a cotreatment with estrogen exhibits antiestrogenic properties on the rodent adult uterus, but less is…”
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Evaluation of Hydroxyatrazine in the Endocrine Disruptor Screening and Testing Program's Male and Female Pubertal Protocols
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01-10-2013)“…Two critical components of the validation of any in vivo screening assay are to demonstrate sensitivity and specificity. Although the Endocrine Disruptor…”
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Lessons learned, challenges, and opportunities: the U.S. Endocrine Disruptor Screening Program
Published in ALTEX, alternatives to animal experimentation (2014)“…In 1996, the U.S. Congress passed the Food Quality Protection Act and amended the Safe Drinking Water Act (SDWA) requiring the U.S. Environmental Protection…”
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Effect of Chlorotriazine Pesticides on Gonadtropin-Releasing Hormone in the Neuronal GT1-7 Cell Line and Hypothalamic Explants
Published in Biology of reproduction (01-07-2009)Get full text
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Effect of Simazine on Pubertal Development and Thyroid Function in the Female Wistar Rat
Published in Biology of reproduction (01-05-2008)Get full text
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Control of luteolytic sensitivity in the porcine corpus luteum
Published 01-01-2007“…The porcine corpus luteum (CL) is unusual in that it does not show a luteolytic response to an exogenous dose of prostaglandin F-2α (PGF-2α) until after day 12…”
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