Search Results - "Zorica Djuric"
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Modeling in the quality by design environment: Regulatory requirements and recommendations for design space and control strategy appointment
Published in International journal of pharmaceutics (30-11-2017)“…[Display omitted] Mathematical models can be used as an integral part of the quality by design (QbD) concept throughout the product lifecycle for variety of…”
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Preparation of carbamazepine–Soluplus® solid dispersions by hot-melt extrusion, and prediction of drug–polymer miscibility by thermodynamic model fitting
Published in European journal of pharmaceutics and biopharmaceutics (01-05-2013)“…Carbamazepine–Soluplus® dispersions were prepared by hot-melt extrusion and characterized in detail. Thermodynamic model fitting was used to predict…”
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Influence of hydrophilic polymers on the complexation of carbamazepine with hydroxypropyl-β-cyclodextrin
Published in European journal of pharmaceutical sciences (12-10-2015)“…[Display omitted] In this study binary carbamazepine–hydroxypropyl-β-cyclodextrin, as well as ternary carbamazepine–hydroxypropyl-β-cyclodextrin–hydrophilic…”
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Dissolution rate enhancement and physicochemical characterization of carbamazepine-poloxamer solid dispersions
Published in Pharmaceutical development and technology (02-04-2016)“…This study investigates the potential of poloxamers as solid dispersions (SDs) carriers in improving the dissolution rate of a poorly soluble drug,…”
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Artificial neural networks in evaluation and optimization of modified release solid dosage forms
Published in Pharmaceutics (18-10-2012)“…Implementation of the Quality by Design (QbD) approach in pharmaceutical development has compelled researchers in the pharmaceutical industry to employ Design…”
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Combined application of mixture experimental design and artificial neural networks in the solid dispersion development
Published in Drug development and industrial pharmacy (03-03-2016)“…This study for the first time demonstrates combined application of mixture experimental design and artificial neural networks (ANNs) in the solid dispersions…”
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Application of failure mode and effects analysis in quality by design approach for formulation of carvedilol compression coated tablets
Published in Journal of drug delivery science and technology (01-04-2016)“…Compression coating technique has been used in formulation of chronotherapeutic drug delivery systems with pulsatile carvedilol release with polyethylene oxide…”
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The influence of spiral jet-milling on the physicochemical properties of carbamazepine form III crystals: Quality by design approach
Published in Chemical engineering research & design (01-03-2014)“…•Design space of jet milling process for model drug was established.•Jet milling used for micronizing of drug preserved its crystal structure.•Critical process…”
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Antimicrobial activity of Helichrysum plicatum DC
Published in Hemijska industrija (2017)“…Dry flower heads of Helichrysum plicatum were characterized by HPLC-DAD and a detailed antimicrobial assay of its ethanol extract was performed. Identification…”
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Optimization of drug release from compressed multi unit particle system (MUPS) using generalized regression neural network (GRNN)
Published in Archives of pharmacal research (2010)“…The purpose of this study was development of diclofenac sodium extended release compressed matrix pellets and optimization using Generalized Regression Neural…”
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An investigation into the usefulness of generalized regression neural network analysis in the development of level A in vitro–in vivo correlation
Published in European journal of pharmaceutical sciences (01-03-2007)“…Quantitative correlations between in vivo and in vitro data (IVIVC) reduce the number of human in vivo studies, thus decreasing the overall time and expenses…”
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Preliminary evaluation of the in vitro release and in vivo absorption in rabbits of the modified-release dosage forms
Published in Drug development and industrial pharmacy (01-06-2013)“…Objective: The suitability of the rabbit as an animal model for the primary screening and selection of the pilot scale batches during the early stages of the…”
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The application of generalized regression neural network in the modeling and optimization of aspirin extended release tablets with Eudragit ® RS PO as matrix substance
Published in Journal of controlled release (21-08-2002)“…The objective of this work is to use a generalized regression neural network (GRNN) in the design of extended-release aspirin tablets. As model formulations,…”
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Antiradical and cytotoxic activity of different Helichrysum plicatum flower extracts
Published in Natural product communications (01-06-2011)“…Flowers of Helichrysum plicatum were extracted under different experimental conditions, and their antioxidant activity was determined by DPPH radical…”
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Application of Mixture Experimental Design in the Formulation and Optimization of Matrix Tablets Containing Carbomer and Hydroxypropylmethylcellulose
Published in Archives of pharmacal research (01-12-2009)“…Using mixture experimental design, the effect of carbomer (Carbopol® 971P NF) and hydroxypropylmethylcellulose (Methocel® K100M or Methocel® K4M) combination…”
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The impact of primary packaging on the quality of parenteral products
Published in Journal of pharmaceutical and biomedical analysis (04-11-2008)“…The unique approach in manufacturing of pharmaceutical dosage forms of active substances known to be unstable in aqueous solution is the introduction of…”
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Artificial intelligence in pharmaceutical product formulation: neural computing
Published in Chemical Industry and Chemical Engineering Quarterly (01-10-2009)“…The properties of a formulation are determined not only by the ratios in which the ingredients are combined but also by the processing conditions. Although the…”
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Artificial neural networks in the modeling and optimization of aspirin extended release tablets with Eudragit L 100 as matrix substance
Published in AAPS PharmSciTech (2003)“…The purpose of the present study was to model the effects of the concentration of Eudragit L 100 and compression pressure as the most important process and…”
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An investigation into effects of In Vitro Test condition on the release properties of theophylline from HPMC matrices using factorial design
Published in Archives of pharmacal research (01-07-2009)“…The purpose of this study was to investigate the effect of various in vitro test conditions, on the release properties of theophylline (TP) from aminophylline…”
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Retraction notice to: Artificial intelligence in pharmaceutical product formulation: Neural computing [Chem. Ind. Chem. Eng. Q. 15(4) (2009) 227-236]
Published in Chemical Industry and Chemical Engineering Quarterly (01-01-2011)“…This article has been retracted at the request of the authors. The retraction has been made because the authors admitted that they took the text and rawings…”
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