Search Results - "Zoppè, Monica"

Towards a perceptive understanding of size in cellular biology by Zoppè, Monica

“…This piece tackles the question of how to make biological scale more intuitive to human beings, bringing to bear the author's background in scientific…”
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Colors in the representation of biological structures by Zoppè, Monica

“…Among the many properties of proteins, sugars, nucleic acids, membranes and other cellular components, color is not present. At the same time, we humans have a…”
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Computational design, fabrication and evaluation of rubber protein models by Alderighi, Thomas, Giorgi, Daniela, Malomo, Luigi, Cignoni, Paolo, Zoppè, Monica

“…•We introduce a complete workflow for the fabrication of soft 3D models of complex proteins.•The workflow enables the fabrication of tangible models of…”
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Integration of Multiple Resolution Data in 3D Chromatin Reconstruction Using ChromStruct by Caudai, Claudia, Zoppè, Monica, Tonazzini, Anna, Merelli, Ivan, Salerno, Emanuele

“…The three-dimensional structure of chromatin in the cellular nucleus carries important information that is connected to physiological and pathological…”
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Intuitive representation of surface properties of biomolecules using BioBlender by Andrei, Raluca Mihaela, Callieri, Marco, Zini, Maria Francesca, Loni, Tiziana, Maraziti, Giuseppe, Pan, Mike Chen, Zoppè, Monica

“…In living cells, proteins are in continuous motion and interaction with the surrounding medium and/or other proteins and ligands. These interactions are…”
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Myocardial contractility in the stress echo lab: from pathophysiological toy to clinical tool by Bombardini, Tonino, Zoppè, Monica, Ciampi, Quirino, Cortigiani, Lauro, Agricola, Eustachio, Salvadori, Stefano, Loni, Tiziana, Pratali, Lorenza, Picano, Eugenio

“…Up-regulation of Ca2+ entry through Ca2+ channels by high rates of beating is involved in the frequency-dependent regulation of contractility: this process is…”
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Transcellular transfer of active HSV-1 thymidine kinase mediated by an 11-amino-acid peptide from HIV-1 Tat by Tasciotti, Ennio, Zoppè, Monica, Giacca, Mauro

“…Suicide gene therapy using herpes simplex virus type-1 (HSV-1) thymidine kinase (TK) is a widely exploited approach for gene therapy of cancer and other…”
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High-level biocontainment laboratories: risks and necessity for society [version 1; peer review: 1 approved, 1 not approved] by Zoppè, Monica

“…Advancements in the biological sciences have made it possible to manipulate life forms in unprecedented ways. Recognizing the possible dangers connected with…”
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Inferring 3D chromatin structure using a multiscale approach based on quaternions by Caudai, Claudia, Salerno, Emanuele, Zoppè, Monica, Tonazzini, Anna

“…The knowledge of the spatial organisation of the chromatin fibre in cell nuclei helps researchers to understand the nuclear machinery that regulates DNA…”
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ChromStruct 4: A Python Code to Estimate the Chromatin Structure from Hi-C Data by Caudai, Claudia, Salerno, Emanuele, Zoppe, Monica, Merelli, Ivan, Tonazzini, Anna

“…A method and a stand-alone Python code to estimate the 3D chromatin structure from chromosome conformation capture data are presented. The method is based on a…”
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Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses by Milan Bonotto, Rafaela, Bonì, Francesco, Milani, Mario, Chaves-Sanjuan, Antonio, Franze, Silvia, Selmin, Francesca, Felicetti, Tommaso, Bolognesi, Martino, Konstantinidou, Soultana, Poggianella, Monica, Márquez, Chantal L., Dattola, Federica, Zoppè, Monica, Manfroni, Giuseppe, Mastrangelo, Eloise, Marcello, Alessandro

“…Pyridobenzothiazolone derivatives are a promising class of broad-spectrum antivirals. However, the mode of action of these compounds remains poorly understood…”
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Step back from the edge by Zoppè, Monica M

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Potentiation of gene targeting in human cells by expression of Saccharomyces cerevisiae Rad52 by Di Primio, Cristina, Galli, Alvaro, Cervelli, Tiziana, Zoppè, Monica, Rainaldi, Giuseppe

“…When exogenous DNA is stably introduced in mammalian cells, it is typically integrated in random positions, and only a minor fraction enters a pathway of…”
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Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells by PENNATI, Marzia, BINDA, Mara, GIACCA, Mauro, DAIDONE, Maria Grazia, ZAFFARONI, Nadia, COLELLA, Gennaro, ZOPPE, Monica, FOLINI, Marco, VIGNATI, Sara, VALENTINI, Alessandra, CITTI, Lorenzo, DE CESARE, Michelandrea, PRATESI, Graziella

“…Survivin is a member of the inhibitor of apoptosis protein (IAP) family, which has been implicated in inhibition of apoptosis and control of mitotic…”
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A Factor IX-Deficient Mouse Model for Hemophilia B Gene Therapy by Wang, Lili, Zoppe, Monica, Hackeng, Tilman M., Griffin, John H., Lee, Kuo-Fen, Verma, Inder M.

“…We have generated a mouse where the clotting factor IX (FIX) gene has been disrupted by homologous recombination. The FIX nullizygous (-/-) mouse was devoid of…”
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The human cytomegalovirus UL45 gene product is a late, virion-associated protein and influences virus growth at low multiplicities of infection by Patrone, Marco, Percivalle, Elena, Secchi, Massimiliano, Fiorina, Loretta, Pedrali-Noy, Guido, Zoppe, Monica, Baldanti, Fausto, Hahn, Gabriele, Koszinowski, Ulrich H, Milanesi, Gabriele, Gallina, Andrea

“…1 Istituto di Genetica Molecolare, CNR, via Abbiategrasso 207, I-27100 Pavia, Italy 2 Servizio di Virologia, IRCCS Policlinico San Matteo, Pavia, Italy 3…”
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Generation of Targeted Retroviral Vectors by Using Single-Chain Variable Fragment: An Approach to in vivo Gene Delivery by Somia, Nikunj V., Zoppe, Monica, Verma, Inder M.

“…We report the generation of a retroviral vector that infects human cells specifically through recognition of the low density lipoprotein receptor. The…”
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Estimation of the Spatial Chromatin Structure Based on a Multiresolution Bead-Chain Model by Caudai, Claudia, Salerno, Emanuele, Zoppe, Monica, Tonazzini, Anna

“…We present a method to infer 3D chromatin configurations from Chromosome Conformation Capture data. Quite a few methods have been proposed to estimate the…”
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Italian defeatism unwarranted by Zoppè, Monica

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Desarrollo de una nueva versión de BioBlender, un módulo de Blender para visualización de biomoléculas by Ramos Bermúdez, Pablo Enmanuel, Pupo Meriño, Mario, Navas Conyedo, Edisel, Zoppé, Monica, Loni, Tiziana

“…Biological macromolecules, such as proteins and nucleic acids, are the main engines of the living cell. Knowing their three-dimensional structure and the way…”
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