Search Results - "Zook, James"

Structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis by Nagaratnam, Nirupa, Martin-Garcia, Jose M, Yang, Jay-How, Goode, Matthew R, Ketawala, Gihan, Craciunescu, Felicia M, Zook, James D, Sonowal, Manashi, Williams, Dewight, Grant, Thomas D, Fromme, Raimund, Hansen, Debra T, Fromme, Petra

“…Francisella tularensis is an extremely infectious pathogen and a category A bioterrorism agent. It causes the highly contagious zoonosis, Tularemia. Currently,…”
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Biophysical characterization and a roadmap towards the NMR solution structure of G0S2, a key enzyme in non-alcoholic fatty liver disease by Moran, Michael W, Ramirez, Elizabeth P, Zook, James D, Saarinen, Alicia M, Baravati, Bobby, Goode, Matthew R, Laloudakis, Vasiliki, Kaschner, Emily K, Olson, Tien L, Craciunescu, Felicia M, Hansen, Debra T, Liu, Jun, Fromme, Petra

“…In the United States non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease, affecting an estimated 80 to 100 million…”
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Diversified farms bolster forest-bird populations despite ongoing declines in tropical forests by Hendershot, J Nicholas, Echeverri, Alejandra, Frishkoff, Luke O, Zook, James R, Fukami, Tadashi, Daily, Gretchen C

“…While some agricultural landscapes can support wildlife in the short term, it is uncertain how well they can truly sustain wildlife populations. To compare…”
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Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography by Olmos, Jr, Jose L, Pandey, Suraj, Martin-Garcia, Jose M, Calvey, George, Katz, Andrea, Knoska, Juraj, Kupitz, Christopher, Hunter, Mark S, Liang, Mengning, Oberthuer, Dominik, Yefanov, Oleksandr, Wiedorn, Max, Heyman, Michael, Holl, Mark, Pande, Kanupriya, Barty, Anton, Miller, Mitchell D, Stern, Stephan, Roy-Chowdhury, Shatabdi, Coe, Jesse, Nagaratnam, Nirupa, Zook, James, Verburgt, Jacob, Norwood, Tyler, Poudyal, Ishwor, Xu, David, Koglin, Jason, Seaberg, Matthew H, Zhao, Yun, Bajt, Saša, Grant, Thomas, Mariani, Valerio, Nelson, Garrett, Subramanian, Ganesh, Bae, Euiyoung, Fromme, Raimund, Fung, Russell, Schwander, Peter, Frank, Matthias, White, Thomas A, Weierstall, Uwe, Zatsepin, Nadia, Spence, John, Fromme, Petra, Chapman, Henry N, Pollack, Lois, Tremblay, Lee, Ourmazd, Abbas, Phillips, Jr, George N, Schmidt, Marius

“…Ever since the first atomic structure of an enzyme was solved, the discovery of the mechanism and dynamics of reactions catalyzed by biomolecules has been the…”
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Purification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor by Zhang, Shangji, Hansen, Debra T., Martin-Garcia, Jose M., Zook, James D., Pan, Shuchong, Craciunescu, Felicia M., Burnett, John C., Fromme, Petra

“…Particulate Guanylyl Cyclase Receptor A (pGC-A) is a natriuretic peptide membrane receptor, playing a vital role in controlling cardiovascular, renal, and…”
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Cicadas impact bird communication in a noisy tropical rainforest by Hart, Patrick J, Hall, Robert, Ray, William, Beck, Angela, Zook, James

“…Many animals communicate through acoustic signaling, and "acoustic space" may be viewed as a limited resource that organisms compete for. If acoustic signals…”
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Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma by Boyd, Ryan J., Olson, Tien L., Zook, James D., Stein, Derek, Aceves, Manuel, Lin, Wan‐Hsin, Craciunescu, Felicia M., Hansen, Debra T., Anastasiadis, Panos Z., Singharoy, Abhishek, Fromme, Petra

“…Structural discovery of guanine nucleotide exchange factor (GEF) protein complexes is likely to become increasingly relevant with the development of new…”
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Co‐flow injection for serial crystallography at X‐ray free‐electron lasers by Doppler, Diandra, Rabbani, Mohammad T., Letrun, Romain, Cruz Villarreal, Jorvani, Kim, Dai Hyun, Gandhi, Sahir, Egatz-Gomez, Ana, Sonker, Mukul, Chen, Joe, Koua, Faisal H. M., Yang, Jayhow, Youssef, Mohamed, Mazalova, Victoria, Bajt, Saša, Shelby, Megan L., Coleman, Matt A., Wiedorn, Max O., Knoska, Juraj, Schön, Silvan, Sato, Tokushi, Hunter, Mark S., Hosseinizadeh, Ahmad, Kuptiz, Christopher, Nazari, Reza, Alvarez, Roberto C., Karpos, Konstantinos, Zaare, Sahba, Dobson, Zachary, Discianno, Erin, Zhang, Shangji, Zook, James D., Bielecki, Johan, de Wijn, Raphael, Round, Adam R., Vagovic, Patrik, Kloos, Marco, Vakili, Mohammad, Ketawala, Gihan K., Stander, Natasha E., Olson, Tien L., Morin, Katherine, Mondal, Jyotirmory, Nguyen, Jonathan, Meza-Aguilar, José Domingo, Kodis, Gerdenis, Vaiana, Sara, Martin-Garcia, Jose M., Mariani, Valerio, Schwander, Peter, Schmidt, Marius, Messerschmidt, Marc, Ourmazd, Abbas, Zatsepin, Nadia, Weierstall, Uwe, Bruce, Barry D., Mancuso, Adrian P., Grant, Thomas, Barty, Anton, Chapman, Henry N., Frank, Matthias, Fromme, Raimund, Spence, John C. H., Botha, Sabine, Fromme, Petra, Kirian, Richard A., Ros, Alexandra

“…Serial femtosecond crystallography (SFX) is a powerful technique that exploits X‐ray free‐electron lasers to determine the structure of macromolecules at room…”
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Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation by Martin-Garcia, Jose M, Conrad, Chelsie E, Nelson, Garrett, Stander, Natasha, Zatsepin, Nadia A, Zook, James, Zhu, Lan, Geiger, James, Chun, Eugene, Kissick, David, Hilgart, Mark C, Ogata, Craig, Ishchenko, Andrii, Nagaratnam, Nirupa, Roy-Chowdhury, Shatabdi, Coe, Jesse, Subramanian, Ganesh, Schaffer, Alexander, James, Daniel, Ketwala, Gihan, Venugopalan, Nagarajan, Xu, Shenglan, Corcoran, Stephen, Ferguson, Dale, Weierstall, Uwe, Spence, John C H, Cherezov, Vadim, Fromme, Petra, Fischetti, Robert F, Liu, Wei

“…Crystal structure determination of biological macromolecules using the novel technique of serial femtosecond crystallography (SFX) is severely limited by the…”
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Full inactivation of alphaviruses in single particle and crystallized forms by Lawrence, Robert M., Zook, James D., Hogue, Brenda G.

“…[Display omitted] •UV irradiation can fully inactivate Sindbis virus as single particles or crystals.•Glutaraldehyde can fully inactivate Sindbis virus as…”
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Protein expression and purification of G-protein coupled receptor kinase 6 (GRK6), toward structure-based drug design and discovery for multiple myeloma by Olson, Tien L., Zhang, Shangji, Labban, Dillon, Kaschner, Emily, Aceves, Manuel, Iyer, Srivatsan, Meza-Aguilar, Jose Domingo, Zook, James D., Chun, Eugene, Craciunescu, Felicia M., Liu, Wei, Shi, Chang-Xin, Stewart, A. Keith, Hansen, Debra T., Meurice, Nathalie, Fromme, Petra

“…Human G-protein coupled receptor kinase 6 (GRK6) belongs to the GRK4 kinase subfamily of the G protein-coupled receptor kinase family which comprises of GRK1,…”
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A novel inert crystal delivery medium for serial femtosecond crystallography by Conrad, Chelsie E, Basu, Shibom, James, Daniel, Wang, Dingjie, Schaffer, Alexander, Roy-Chowdhury, Shatabdi, Zatsepin, Nadia A, Aquila, Andrew, Coe, Jesse, Gati, Cornelius, Hunter, Mark S, Koglin, Jason E, Kupitz, Christopher, Nelson, Garrett, Subramanian, Ganesh, White, Thomas A, Zhao, Yun, Zook, James, Boutet, Sébastien, Cherezov, Vadim, Spence, John C H, Fromme, Raimund, Weierstall, Uwe, Fromme, Petra

“…Serial femtosecond crystallography (SFX) has opened a new era in crystallo-graphy by permitting nearly damage-free, room-temperature structure determination of…”
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Low Temperature Assembly of Functional 3D DNA-PNA-Protein Complexes by Flory, Justin D, Simmons, Chad R, Lin, Su, Johnson, Trey, Andreoni, Alessio, Zook, James, Ghirlanda, Giovanna, Liu, Yan, Yan, Hao, Fromme, Petra

“…Proteins have evolved to carry out nearly all the work required of living organisms within complex inter- and intracellular environments. However,…”
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The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography by Edlund, Petra, Takala, Heikki, Claesson, Elin, Henry, Léocadie, Dods, Robert, Lehtivuori, Heli, Panman, Matthijs, Pande, Kanupriya, White, Thomas, Nakane, Takanori, Berntsson, Oskar, Gustavsson, Emil, Båth, Petra, Modi, Vaibhav, Roy-Chowdhury, Shatabdi, Zook, James, Berntsen, Peter, Pandey, Suraj, Poudyal, Ishwor, Tenboer, Jason, Kupitz, Christopher, Barty, Anton, Fromme, Petra, Koralek, Jake D., Tanaka, Tomoyuki, Spence, John, Liang, Mengning, Hunter, Mark S., Boutet, Sebastien, Nango, Eriko, Moffat, Keith, Groenhof, Gerrit, Ihalainen, Janne, Stojković, Emina A., Schmidt, Marius, Westenhoff, Sebastian

“…Phytochromes are a family of photoreceptors that control light responses of plants, fungi and bacteria. A sequence of structural changes, which is not yet…”
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Coherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source by Munke, Anna, Andreasson, Jakob, Aquila, Andrew, Awel, Salah, Ayyer, Kartik, Barty, Anton, Bean, Richard J., Berntsen, Peter, Bielecki, Johan, Boutet, Sébastien, Bucher, Maximilian, Chapman, Henry N., Daurer, Benedikt J., DeMirci, Hasan, Elser, Veit, Fromme, Petra, Hajdu, Janos, Hantke, Max F., Higashiura, Akifumi, Hogue, Brenda G., Hosseinizadeh, Ahmad, Kim, Yoonhee, Kirian, Richard A., Reddy, Hemanth K.N., Lan, Ti-Yen, Larsson, Daniel S.D., Liu, Haiguang, Loh, N. Duane, Maia, Filipe R.N.C., Mancuso, Adrian P., Mühlig, Kerstin, Nakagawa, Atsushi, Nam, Daewoong, Nelson, Garrett, Nettelblad, Carl, Okamoto, Kenta, Ourmazd, Abbas, Rose, Max, van der Schot, Gijs, Schwander, Peter, Seibert, M. Marvin, Sellberg, Jonas A., Sierra, Raymond G., Song, Changyong, Svenda, Martin, Timneanu, Nicusor, Vartanyants, Ivan A., Westphal, Daniel, Wiedorn, Max O., Williams, Garth J., Xavier, Paulraj Lourdu, Yoon, Chun Hong, Zook, James

“…Single particle diffractive imaging data from Rice Dwarf Virus (RDV) were recorded using the Coherent X-ray Imaging (CXI) instrument at the Linac Coherent…”
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Birds as agents of seed dispersal in a human-dominated landscape in southern Costa Rica by Pejchar, Liba, Pringle, Robert M., Ranganathan, Jai, Zook, James R., Duran, Guillermo, Oviedo, Federico, Daily, Gretchen C.

“…Birds play vital roles as seed dispersers helping to maintain and restore plant communities. With restoration increasingly key to global conservation, it is…”
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High-resolution NMR reveals secondary structure and folding of amino acid transporter from outer chloroplast membrane by Zook, James D, Molugu, Trivikram R, Jacobsen, Neil E, Lin, Guangxin, Soll, Jürgen, Cherry, Brian R, Brown, Michael F, Fromme, Petra

“…Solving high-resolution structures for membrane proteins continues to be a daunting challenge in the structural biology community. In this study we report our…”
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XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia by Zook, James, Shekhar, Mrinal, Hansen, Debra, Conrad, Chelsie, Grant, Thomas, Gupta, Chitrak, White, Thomas, Barty, Anton, Basu, Shibom, Zhao, Yun, Zatsepin, Nadia, Ishchenko, Andrii, Batyuk, Alex, Gati, Cornelius, Li, Chufeng, Galli, Lorenzo, Coe, Jesse, Hunter, Mark, Liang, Meng, Weierstall, Uwe, Nelson, Garret, James, Daniel, Stauch, Benjamin, Craciunescu, Felicia, Thifault, Darren, Liu, Wei, Cherezov, Vadim, Singharoy, Abhishek, Fromme, Petra

“…Francisella tularensis is the causative agent for the potentially fatal disease tularemia. The lipoprotein Flpp3 has been identified as a virulence determinant…”
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XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia by Zook, James, Shekhar, Mrinal, Hansen, Debra, Conrad, Chelsie, Grant, Thomas, Gupta, Chitrak, White, Thomas, Barty, Anton, Basu, Shibom, Zhao, Yun, Zatsepin, Nadia, Ishchenko, Andrii, Batyuk, Alex, Gati, Cornelius, Li, Chufeng, Galli, Lorenzo, Coe, Jesse, Hunter, Mark, Liang, Meng, Weierstall, Uwe, Nelson, Garret, James, Daniel, Stauch, Benjamin, Craciunescu, Felicia, Thifault, Darren, Liu, Wei, Cherezov, Vadim, Singharoy, Abhishek, Fromme, Petra

“…Francisella tularensis is the causative agent for the potentially fatal disease tularemia. The lipoprotein Flpp3 has been identified as a virulence determinant…”
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XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia by Zook, James, Shekhar, Mrinal, Hansen, Debra, Conrad, Chelsie, Grant, Thomas, Gupta, Chitrak, White, Thomas, Barty, Anton, Basu, Shibom, Zhao, Yun, Zatsepin, Nadia, Ishchenko, Andrii, Batyuk, Alex, Gati, Cornelius, Li, Chufeng, Galli, Lorenzo, Coe, Jesse, Hunter, Mark, Liang, Meng, Weierstall, Uwe, Nelson, Garret, James, Daniel, Stauch, Benjamin, Craciunescu, Felicia, Thifault, Darren, Liu, Wei, Cherezov, Vadim, Singharoy, Abhishek, Fromme, Petra

“…Francisella tularensis is the causative agent for the potentially fatal disease tularemia. The lipoprotein Flpp3 has been identified as a virulence determinant…”
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