Search Results - "Zong, Yaping"
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Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3β/β-catenin pathways
Published in Molecular cancer (29-03-2017)“…Metastasis is a major cause of death in human colorectal cancer patients. However, the contribution of chemokines in the tumor microenvironment to tumor…”
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KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response
Published in Cell death & disease (05-04-2022)“…Oxaliplatin resistance is a major challenge in the treatment of colorectal cancer (CRC). Many molecular targeted drugs for refractory CRC have been developed…”
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3
Dysbiosis of human tumor microbiome and aberrant residence of Actinomyces in tumor-associated fibroblasts in young-onset colorectal cancer
Published in Frontiers in immunology (02-09-2022)“…Colorectal cancer (CRC) is the third most common form of cancer, and the incidence of sporadic young-onset colorectal cancer (yCRC) has been increasing…”
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4
Cytokine concentration in peripheral blood of patients with colorectal cancer
Published in Frontiers in immunology (30-03-2023)“…The role of tumour secretory cytokines and peripheral circulatory cytokines in tumour progression has received increasing attention; however, the role of…”
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Colorectal cancer tissue-originated spheroids reveal tumor intrinsic signaling pathways and mimic patient clinical chemotherapeutic response as a rapid and valid model
Published in Biomedicine & pharmacotherapy (01-11-2023)“…Locally advanced colorectal cancer requires preoperative chemotherapy to reduce local recurrence and metastasis rates, but it remains difficult to predict the…”
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6
Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein
Published in The Journal of biological chemistry (03-06-2011)“…In mammals, the transcriptional activity of signal transducer and activator of transcription 3 (STAT3) is regulated by the deacetylase SIRT1. However, whether…”
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7
Graphene Adhesion Mechanics on Iron Substrates: Insight from Molecular Dynamic Simulations
Published in Crystals (Basel) (01-11-2019)“…The adhesion feature of graphene on metal substrates is important in graphene synthesis, transfer and applications, as well as for graphene-reinforced metal…”
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8
Intracorporeal versus extracorporeal anastomosis in laparoscopic right colectomy: a retrospective study
Published in World journal of surgical oncology (20-05-2023)“…The surgical procedure for laparoscopic right colectomy (LRC) is not standardized. Some published studies show the superiority of ileocolic anastomosis (IIA),…”
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9
The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple Prosurvival Pathways through IGF1R
Published in The Journal of biological chemistry (28-08-2009)“…Recent molecular studies indicate that aerobic glycolysis plays an important role in tumorigenesis and is a valid target for cancer therapy. Although…”
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10
Small molecule inhibitors from organoid‐based drug screen induce concurrent apoptosis and gasdermin E‐dependent pyroptosis in colorectal cancer
Published in Clinical and translational medicine (01-04-2022)“…The extracted cell aggregates consisted of almost pure tumour cells with few immune or vascular endothelial cells (Figures 1E and S1D,E). Since cancer stem…”
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Prediction of Target Genes and Pathways Associated With Cetuximab Insensitivity in Colorectal Cancer
Published in Technology in cancer research & treatment (01-01-2018)“…Background: Cetuximab has been regularly added to the treatments for metastatic colorectal cancer worldwide. However, due to its therapeutic insensitivity and…”
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12
PFDN1, an indicator for colorectal cancer prognosis, enhances tumor cell proliferation and motility through cytoskeletal reorganization
Published in Medical oncology (Northwood, London, England) (01-12-2015)“…Prefoldin (PFDN) subunits have been reported upregulated in various tumor types, while the expression and functions of PFDN1 (PFDN subunit 1) in colorectal…”
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13
Was the Scanner Calibration Slide used for its intended purpose?
Published in BMC bioinformatics (21-04-2011)“…In the article, Scanner calibration revisited, BMC Bioinformatics 2010, 11:361, Dr. Pozhitkov used the Scanner Calibration Slide, a key product of Full Moon…”
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14
Strengthening mechanism of load sharing of particulate reinforcements in a metal matrix composite
Published in Journal of materials science (01-06-2007)“…A 15 v% SiC particle reinforced Al-2618 matrix composite was selected to study strengthening mechanisms under different heat treatments to produce specimens in…”
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15
Sensing the insulin signaling pathway with an antibody array
Published in Proteomics. Clinical applications (01-12-2009)“…The development of insulin resistance and type 2 diabetes is determined by various factors, including defects within the insulin signaling pathway. Mediators…”
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Stress in particulate reinforcements and overall stress response on aluminum alloy matrix composites during straining by analytical and numerical modeling
Published in Computational materials science (01-10-2008)“…SiC and Al2O3 (10–20v%) particle-reinforced Al-2618 matrix composites subjected to tensile loading were selected to simulate stress–strain curves and average…”
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CCL19 suppresses angiogenesis through promoting miR-206 and inhibiting Met/ERK/Elk-1/HIF-1α/VEGF-A pathway in colorectal cancer
Published in Cell death & disease (24-09-2018)“…The mechanisms underlying the role of chemokines in tumor angiogenesis is still not fully understood. In this study, we detected the influence of CCL19 on…”
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Effect of interfacial bonding on dislocation strengthening in graphene nanosheet reinforced iron composite: A molecular dynamics study
Published in Computational materials science (15-04-2021)“…[Display omitted] It is uncertain that the interfacial bonding is whether a strong chemical bond or a weak van der-Waals one in graphene-metal composites. The…”
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High versus low ligation of the inferior mesenteric artery during laparoscopic rectal cancer surgery: A prospective study of surgical and oncological outcomes
Published in Journal of surgical oncology (01-05-2021)“…Background and Objectives There is controversy regarding whether the inferior mesenteric artery (IMA) should be ligated at its origin from the aorta (high…”
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Platelet infiltration predicts survival in postsurgical colorectal cancer patients
Published in International journal of cancer (01-02-2022)“…Platelets promote tumor growth and metastasis in several tumor types. Recent research has found platelets can extravasate and infiltrate into the tumor stroma…”
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