Search Results - "Zona, S."

FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cells by Yang, N, Wang, C, Wang, Z, Zona, S, Lin, S-X, Wang, X, Yan, M, Zheng, F-M, Li, S-S, Xu, B, Bella, L, Yong, J-S, Lam, E W-F, Liu, Q

“…Substantial evidence suggests that breast cancer initiation, recurrence and drug resistance is supported by breast cancer stem cells (BCSCs). Recently, we…”
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OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance by Karunarathna, U, Kongsema, M, Zona, S, Gong, C, Cabrera, E, Gomes, A R, Man, E P S, Khongkow, P, Tsang, J W-H, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F

“…The forkhead transcription factor FOXM1 has a key role in DNA damage response, and its deregulated overexpression is associated with genotoxic drug resistance…”
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FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance by Khongkow, P, Karunarathna, U, Khongkow, M, Gong, C, Gomes, A R, Yagüe, E, Monteiro, L J, Kongsema, M, Zona, S, Man, E P S, Tsang, J W-H, Coombes, R C, Wu, K-J, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F

“…FOXM1 is implicated in genotoxic drug resistance but its mechanism of action remains elusive. We show here that FOXM1-depletion can sensitize breast cancer…”
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SUMOylation inhibits FOXM1 activity and delays mitotic transition by Myatt, S S, Kongsema, M, Man, C W-Y, Kelly, D J, Gomes, A R, Khongkow, P, Karunarathna, U, Zona, S, Langer, J K, Dunsby, C W, Coombes, R C, French, P M, Brosens, J J, Lam, E W-F

“…The forkhead box transcription factor FOXM1 is an essential effector of G2/M-phase transition, mitosis and the DNA damage response. As such, it is frequently…”
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Serum total estradiol, but not testosterone is associated with reduced bone mineral density (BMD) in HIV-infected men: a cross-sectional, observational study by Santi, D., Madeo, B., Carli, F., Zona, S., Brigante, G., Vescini, F., Guaraldi, G., Rochira, V.

“…Summary By investigating the relationship between serum testosterone, estradiol, and bone mineral density (BMD) in a large cohort of HIV-infected men,…”
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Significant chronic airway abnormalities in never‐smoking HIV‐infected patients by Besutti, G, Santoro, A, Scaglioni, R, Neri, S, Zona, S, Malagoli, A, Orlando, G, Beghè, B, Ligabue, G, Torricelli, P, Manfredini, M, Pellacani, G, Fabbri, LM, Guaraldi, G

“…Objectives The aim of the study was to describe chronic lung disease in HIV‐infected never‐smokers by looking at clinical, structural and functional…”
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How to manage children if a second wave of COVID-19 occurs by Esposito, S., Zona, S., Vergine, G., Fantini, M., Marchetti, F., Stella, M., Valletta, E., Biasucci, G., Lanari, M., Dodi, I., Bigi, M., Magista, A. M., Vaienti, F., Cella, A., Affanni, P., Re, M. C., Sambri, V., Principi, N., on behalf of the Regione Emilia-Romagna COVID-19 Paediatric Working Group (RERCOPed)

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The natural history of HIV‐associated lipodystrophy in the changing scenario of HIV infection by Guaraldi, G, Stentarelli, C, Zona, S, Santoro, A, Beghetto, B, Carli, F, Orlando, G, Franceschetto, A, Casolo, A, Mussini, C

“…Objectives In long‐term HIV‐infected patients, peripheral lipoatrophy (LA) and central lipohypertrophy (LH) appear to be related to the same insults (virus and…”
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EPICARDIAL ADIPOSE TISSUE AND CORONARY ARTERY CALCIUM INDEPENDENTLY PREDICT INCIDENT MYOCARDIAL INFARCTION AND DEATH IN HIV-INFECTED PATIENTS by Raggi, P, Zona, S, Bellasi, A, Guaraldi, G

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RNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatment by Kongsema, M, Zona, S, Karunarathna, U, Cabrera, E, Man, E P S, Yao, S, Shibakawa, A, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F

“…The forkhead box M1 (FOXM1) transcription factor has a central role in genotoxic agent response in breast cancer. FOXM1 is regulated at the post-translational…”
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Low testosterone is associated with poor health status in men with human immunodeficiency virus infection: a retrospective study by Rochira, V., Diazzi, C., Santi, D., Brigante, G., Ansaloni, A., Decaroli, M. C., De Vincentis, S., Stentarelli, C., Zona, S., Guaraldi, G.

“…Summary Men with human immunodeficiency virus (HIV) infection are often hypogonadal and develop several HIV‐associated non‐acquired immunodeficiency syndrome…”
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Surrogate markers of visceral adipose tissue in treated HIV‐infected patients: accuracy of waist circumference determination by Falutz, J, Rosenthall, L, Kotler, D, Zona, S, Guaraldi, G

“…Objectives The accuracy of the use of anthropometrics to quantify visceral adipose tissue (VAT) in treated HIV‐infected patients is unknown. We evaluated the…”
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Independent association of subclinical coronary artery disease and emphysema in HIV‐infected patients by Besutti, G, Raggi, P, Zona, S, Scaglioni, R, Santoro, A, Orlando, G, Ligabue, G, Leipsic, J, Sin, DD, Man, SFP, Guaraldi, G

“…Objectives Chronic obstructive pulmonary disease (COPD) and coronary artery disease are inflammatory states with a significant clinical impact. The…”
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Raphides in Palm Embryos and their Systematic Distribution by ZONA, SCOTT

“…• Background and Aims Raphides are ubiquitous in the palms (Arecaceae), where they are found in roots, stems, leaves, flowers and fruits. Their occasional…”
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Incidence and factors associated with the risk of sexually transmitted diseases in HIV‐infected people seen for care in Italy: data from the Icona Foundation cohort by Cingolani, A, Zona, S, Girardi, E, Cozzi‐Lepri, A, Monno, L, Quiros Roldan, E, Guaraldi, G, Antinori, A, D'Arminio Monforte, A, Marcotullio, S

“…Objectives The aims of this study were to identify temporal trends in the incidence of sexually transmitted diseases (STDs) in a cohort of HIV‐infected people…”
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Differential Dose Adjustments of Immunosuppressants after Resuming Boosted versus Unboosted HIV‐Protease Inhibitors Postliver Transplant by Guaraldi, G., Cocchi, S., Motta, A., Ciaffi, S., Conti, C., Codeluppi, M., Bonora, S., Zona, S., Di Benedetto, F., Pinetti, D., D’Avolio, A., Bertolini, A., Esposito, R.

“…Pharmacokinetic (PK) interactions between protease inhibitors (PIs) and immunosuppressive agents (IS) are critical elements in the management of HIV‐infected…”
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Hyperhomocysteinaemia in HIV‐infected patients: determinants of variability and correlations with predictors of cardiovascular disease by Guaraldi, G, Ventura, P, Garlassi, E, Orlando, G, Squillace, N, Nardini, G, Stentarelli, C, Zona, S, Marchini, S, Moriondo, V, Tebas, P

“…Objective We evaluated hyperhomocysteinaemia (HHcy) in a cohort of HIV‐infected patients in order to assess its relation to cardiovascular risk (CVR) and…”
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Premature Age-Related Comorbidities Among HIV-Infected Persons Compared With the General Population by Guaraldi, Giovanni, Orlando, Gabriella, Zona, Stefano, Menozzi, Marianna, Carli, Federica, Garlassi, Elisa, Berti, Alessandra, Rossi, Elisa, Roverato, Alberto, Palella, Frank

“…Background. Human immunodeficiency virus (HlV)-infected patients may have a greater risk of noninfectious comorbidities (NICMs) compared with the general…”
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PCR246 Patient Perspectives on Non-Medical Switching by Doherty, B., Patel, A., Zona, S., Geonnotti, G., Peters, W., Shea, L.

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36P In-vitro tonic signalling profiling of CAR-T cells generated to support pre-clinical studies for solid tumour targets by Hunjan, S.S., Sampson, R., Evans, J., Chenoweth, H., Garrobo-Calleja, I., Lekomtsev, S., Zhang, J., Zona, S., Breuning, J., Oren, R., Davies, M., Di-Tullio, A., Euesden, J., Kennedy, J., Kay, C., Colebrook, J., Kloke, B.P., Southgate, T., Lee, J.

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