Search Results - "Zompra, A."
-
1
Identification and characterisation of short chain rhamnolipid production in a previously uninvestigated, non-pathogenic marine pseudomonad
Published in Applied microbiology and biotechnology (01-10-2018)“…This study aimed to identify and characterise biosurfactant compounds produced by bacteria associated with a marine eukaryotic phytoplankton bloom. One strain,…”
Get full text
Journal Article -
2
Reliable Characterization of Organic & Pharmaceutical Compounds with High Resolution Monochromated EEL Spectroscopy
Published in Polymers (27-06-2020)“…Organic and biological compounds (especially those related to the pharmaceutical industry) have always been of great interest for researchers due to their…”
Get full text
Journal Article -
3
Metabolite and Bioactive Compounds Profiling of Meteora Sea Buckthorn Berries through High-Resolution NMR Analysis
Published in Metabolites (30-11-2021)“…Sea buckthorn berries ( L.) (SB) are considered as a fruit with a high nutritional value with a plethora of bioactive ingredients. The present work focusses on…”
Get full text
Journal Article -
4
Mapping of the sGC Stimulator BAY 41-2272 Binding Site on H-NOX Domain and Its Regulation by the Redox State of the Heme
Published in Frontiers in cell and developmental biology (17-06-2022)“…Soluble guanylate cyclase (sGC) is the main receptor of nitric oxide (NO) and by converting GTP to cGMP regulates numerous biological processes. The β 1…”
Get full text
Journal Article -
5
Marine-Derived Surface Active Agents: Health-Promoting Properties and Blue Biotechnology-Based Applications
Published in Biomolecules (Basel, Switzerland) (09-06-2020)“…Surface active agents are characterized for their capacity to adsorb to fluid and solid-water interfaces. They can be classified as surfactants and emulsifiers…”
Get full text
Journal Article -
6
A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro
Published in Journal of cellular biochemistry (01-06-2011)“…Pleiotrophin (PTN) is a heparin‐binding growth factor that plays a significant role in tumor growth and angiogenesis. We have previously shown that in order…”
Get full text
Journal Article -
7
Multi-method biophysical analysis in discovery, identification, and in-depth characterization of surface‐active compounds
Published in Frontiers in Marine Science (20-10-2022)“…Synthetic surfactants are used in several industries, including manufacturing, pharmaceutical and cosmetic’s, food and feed, agriculture, petroleum and…”
Get full text
Journal Article -
8
Manufacturing peptides as active pharmaceutical ingredients
Published in Future medicinal chemistry (01-05-2009)“…Today, there are more than 40 peptides on the pharmaceutical world market and more than 100 in several clinical phases. Although in the past the pharmaceutical…”
Get more information
Journal Article -
9
Pleiotrophin selectively binds to vascular endothelial growth factor receptor 2 and inhibits or stimulates cell migration depending on ανβ3 integrin expression
Published in Angiogenesis (London) (01-11-2020)“…Pleiotrophin (PTN) has a moderate stimulatory effect on endothelial cell migration through α ν β 3 integrin, while it decreases the stimulatory effect of…”
Get full text
Journal Article -
10
Gonadotropin-releasing Hormone Analogues Alter Gene Expression of Metalloproteinases and their Tissue Inhibitors in Human Breast Cancer Epithelial Cells
Published in Anticancer research (01-11-2006)“…Luteinizing hormone-releasing hormone (LHRH or GnRH) is not only produced by hypothalamus, but also by other normal and cancer tissues. GnRH peptide agonists…”
Get full text
Journal Article -
11
Unraveling the aggregation propensity of human insulin C‐peptide
Published in Biopolymers (01-03-2017)“…ABSTRACT Over the last 20 years, proinsulin C‐peptide emerged as an important player in various biological events. Much time and effort has been spent in…”
Get full text
Journal Article -
12
Synthesis, liposomal formulation and thermal effects on phospholipid bilayers of leuprolide
Published in Journal of peptide science (01-01-2006)“…A novel liposomal formulation was developed for the encapsulation of the oligopeptide leuprolide (GlpHisTrpSerTyr‐D‐LeuLeuArgProNHEt), a potent analogue of…”
Get full text
Journal Article -
13
RADA-16: A Tough Peptide - Strategies for Synthesis and Purification
Published in European journal of organic chemistry (01-09-2013)“…The self‐assembling capacity of certain molecules can be exploited for a diverse range of biomedical applications. The ionic complementary peptide RADA‐16 is…”
Get full text
Journal Article -
14
Structural studies and cytotoxicity assays of "aggregation-prone" IAPP(8-16) and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin
Published in Biopolymers (01-05-2015)“…Amyloid deposits to the islets of Langerhans are responsible for the gradual loss of pancreatic β-cells leading to type II diabetes mellitus. Human mature…”
Get full text
Journal Article -
15
Structural studies and cytotoxicity assays of "aggregation-prone" IAPP8-16 and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin
Published in Peptide Science (01-05-2015)“…ABSTRACT Amyloid deposits to the islets of Langerhans are responsible for the gradual loss of pancreatic β‐cells leading to type II diabetes mellitus. Human…”
Get full text
Journal Article -
16
Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies
Published in Biopolymers (2012)“…Lamprey gonadotropin‐releasing hormone type III (lGnRH‐III) is an isoform of GnRH isolated from the sea lamprey (Petromyzon marinus) with negligible endocrine…”
Get full text
Journal Article -
17
Enzymatic stability, solution structure, and antiproliferative effect on prostate cancer cells of leuprolide and new gonadotropin-releasing hormone peptide analogs
Published in Biopolymers (2011)“…Analogs of GnRH, including [DLeu6, desGly10]‐GnRH‐NHEt (leuprolide, commercial product), have been widely used in oncology to induce reversible chemical…”
Get full text
Journal Article -
18
GnRH analogues containing conformationally restricted amino acids in positions 3 and 6: differential impact on pituitary binding affinity and direct antiproliferative effect on breast cancer cells
Published in The journal of peptide research (01-12-2005)“…: Analogues of GnRH have been widely used in oncology and gynaecology to induce reversible chemical castration. In addition to the classic hypophysiotropic…”
Get full text
Journal Article -
19
The heat stability of Rhamnolipid containing egg-protein stabilised oil-in-water emulsions
Published in Food hydrocolloids (01-07-2021)“…The heat stability of egg white stabilised emulsions was studied in the presence of monoglycerides, lecithin and rhamnolipid biosurfactants. Rhamnolipids have…”
Get full text
Journal Article -
20
Synthesis and Biological Evaluation of New GnRH Analogues on Pituitary and Breast Cancer Cells
Published in International journal of peptide research and therapeutics (01-06-2007)“…GnRH analogues have been extensively used in oncology to induce reversible chemical castration due to their hypophysiotropic action. In addition to that, it…”
Get full text
Journal Article