Search Results - "Zoltsman, Guy"

Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions by Sekhar, Ashok, Velyvis, Algirdas, Zoltsman, Guy, Rosenzweig, Rina, Bouvignies, Guillaume, Kay, Lewis E

“…Molecular recognition is integral to biological function and frequently involves preferred binding of a molecule to one of several exchanging ligand…”
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Structural basis for UFM1 transfer from UBA5 to UFC1 by Kumar, Manoj, Padala, Prasanth, Fahoum, Jamal, Hassouna, Fouad, Tsaban, Tomer, Zoltsman, Guy, Banerjee, Sayanika, Cohen-Kfir, Einav, Dessau, Moshe, Rosenzweig, Rina, Isupov, Michail N., Schueler-Furman, Ora, Wiener, Reuven

“…Ufmylation is a post-translational modification essential for regulating key cellular processes. A three-enzyme cascade involving E1, E2 and E3 is required for…”
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Macrophage Migration Inhibitory Factor as a Chaperone Inhibiting Accumulation of Misfolded SOD1 by Israelson, Adrian, Ditsworth, Dara, Sun, Shuying, Song, SungWon, Liang, Jason, Hruska-Plochan, Marian, McAlonis-Downes, Melissa, Abu-Hamad, Salah, Zoltsman, Guy, Shani, Tom, Maldonado, Marcus, Bui, Anh, Navarro, Michael, Zhou, Huilin, Marsala, Martin, Kaspar, Brian K., Da Cruz, Sandrine, Cleveland, Don W.

“…Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by loss of motor neurons and…”
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MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS by Shvil, Neta, Banerjee, Victor, Zoltsman, Guy, Shani, Tom, Kahn, Joy, Abu-Hamad, Salah, Papo, Niv, Engel, Stanislav, Bernhagen, Jurgen, Israelson, Adrian

“…Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease caused by the progressive loss of motor…”
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Meet the authors: Guy Zoltsman and Rina Rosenzweig by Zoltsman, Guy, Rosenzweig, Rina

“…We talk to first and last authors Guy Zoltsman and Rina Rosenzweig about their paper, "A unique chaperoning mechanism in Class A JDPs recognizes and stabilizes…”
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Hsp104 N‐terminal domain interaction with substrates plays a regulatory role in protein disaggregation by Harari, Anna, Zoltsman, Guy, Levin, Tal, Rosenzweig, Rina

“…Heat shock protein 104 (Hsp104) protein disaggregases are powerful molecular machines that harness the energy derived from ATP binding and hydrolysis to…”
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Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation by Banerjee, Sayanika, Varga, Julia K, Kumar, Manoj, Zoltsman, Guy, Rotem‐Bamberger, Shahar, Cohen‐Kfir, Einav, Isupov, Michail N, Rosenzweig, Rina, Schueler‐Furman, Ora, Wiener, Reuven

“…Ufmylation plays a crucial role in various cellular processes including DNA damage response, protein translation, and ER homeostasis. To date, little is known…”
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