Search Results - "Zolkova Jana"

Comparison of clinical phenotype with genetic and laboratory results in 31 patients with congenital dysfibrinogenemia in northern Slovakia by Simurda, Tomas, Zolkova, Jana, Kolkova, Zuzana, Loderer, Dusan, Dobrotova, Miroslava, Skornova, Ingrid, Brunclíkova, Monika, Grendar, Marian, Lasabova, Zora, Stasko, Jan, Kubisz, Peter

“…Congenital dysfibrinogenemia (CD) is a rare disorder of hemostasis. The majority of cases are caused by heterozygous missense mutations in one of the three…”
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Genetic Variants in the FGB and FGG Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders Associated with a Thrombotic Phenotype by Simurda, Tomas, Brunclikova, Monika, Asselta, Rosanna, Caccia, Sonia, Zolkova, Jana, Kolkova, Zuzana, Loderer, Dusan, Skornova, Ingrid, Hudecek, Jan, Lasabova, Zora, Stasko, Jan, Kubisz, Peter

“…Fibrinogen is a hexameric plasmatic glycoprotein composed of pairs of three chains (Aα, Bβ, and γ), which play an essential role in hemostasis. Conversion of…”
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Molecular Pathology of Hematologic Malignancies by Zolkova Jana, Simonova Radoslava, Lenka, Lisa, Sokol Juraj, Pec Martin

“…Hematological malignancies represent a heterogeneous group of diseases that may have overlapping clinical manifestations. Successful and optimal management…”
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Congenital hypofibrinogenemia associated with a novel heterozygous nonsense mutation in the globular C-terminal domain of the γ-chain (p.Glu275Stop) by Simurda, Tomas, Caccia, Sonia, Asselta, Rosanna, Zolkova, Jana, Stasko, Jan, Skornova, Ingrid, Snahnicanova, Zuzana, Loderer, Dusan, Lasabova, Zora, Kubisz, Peter

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Impact of Dabigatran Treatment on Rotation Thromboelastometry by Sokol, Juraj, Nehaj, Frantisek, Ivankova, Jela, Mokan, Michal, Zolkova, Jana, Lisa, Lenka, Linekova, Ludmila, Mokan, Marian, Stasko, Jan

“…A rapid and reliable assessment of the dabigatran effect is desirable in dabigatran treated patients with uncontrolled bleeding or before acute surgery. The…”
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Identification of Two Novel Fibrinogen Bβ Chain Mutations in Two Slovak Families with Quantitative Fibrinogen Disorders by Simurda, Tomas, Zolkova, Jana, Snahnicanova, Zuzana, Loderer, Dusan, Skornova, Ingrid, Sokol, Juraj, Hudecek, Jan, Stasko, Jan, Lasabova, Zora, Kubisz, Peter

“…Congenital fibrinogen disorders are caused by mutations in one of the three fibrinogen genes that affect the synthesis, assembly, intracellular processing,…”
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How can Secondary Thromboprophylaxis in High-Risk Pregnant Patients be Improved? by Stanciakova, Lucia, Dobrotova, Miroslava, Holly, Pavol, Zolkova, Jana, Vadelova, Lubica, Skornova, Ingrid, Ivankova, Jela, Samos, Matej, Bolek, Tomas, Grendar, Marian, Danko, Jan, Kubisz, Peter, Stasko, Jan

“…Low-molecular-weight heparin (LMWH) is suggested for thromboprophylaxis in pregnant women with previous venous thromboembolism (VTE). Anyway, there is only…”
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Basic Principles of Rotational Thromboelastometry (ROTEM ® ) and the Role of ROTEM-Guided Fibrinogen Replacement Therapy in the Management of Coagulopathies by Drotarova, Miroslava, Zolkova, Jana, Belakova, Kristina Maria, Brunclikova, Monika, Skornova, Ingrid, Stasko, Jan, Simurda, Tomas

“…Rotational thromboelastometry (ROTEM) is a viscoelastic method, which provides a graphical and numerical representation of induced hemostasis in whole blood…”
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Congenital Afibrinogenemia and Hypofibrinogenemia: Laboratory and Genetic Testing in Rare Bleeding Disorders with Life-Threatening Clinical Manifestations and Challenging Management by Simurda, Tomas, Asselta, Rosanna, Zolkova, Jana, Brunclikova, Monika, Dobrotova, Miroslava, Kolkova, Zuzana, Loderer, Dusan, Skornova, Ingrid, Hudecek, Jan, Lasabova, Zora, Stasko, Jan, Kubisz, Peter

“…Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative (afibrinogenemia, hypofibrinogenemia) and qualitative…”
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Impact of Edoxaban on Thrombin-Dependent Platelet Aggregation by Sokol, Juraj, Nehaj, Frantisek, Ivankova, Jela, Mokan, Michal, Lisa, Lenka, Zolkova, Jana, Vadelova, Lubica, Mokan, Marian, Stasko, Jan

“…Edoxaban, a direct factor Xa inhibitor (FXa), is the fourth direct oral anticoagulant (DOAC) approved for clinical use. As the main adverse event is bleeding,…”
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A Novel Nonsense Mutation in FGB (c.1421G>A; p.Trp474Ter) in the Beta Chain of Fibrinogen Causing Hypofibrinogenemia with Bleeding Phenotype by Simurda, Tomas, Vilar, Rui, Zolkova, Jana, Ceznerova, Eliska, Kolkova, Zuzana, Loderer, Dusan, Neerman-Arbez, Marguerite, Casini, Alessandro, Brunclikova, Monika, Skornova, Ingrid, Dobrotova, Miroslava, Grendar, Marian, Stasko, Jan, Kubisz, Peter

“…Congenital hypofibrinogenemia is a rare bleeding disorder characterized by a proportional decrease of functional and antigenic fibrinogen levels…”
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Platelet miRNA Expression in Patients with Sticky Platelet Syndrome by Belakova, Kristina Maria, Zolkova, Jana, Vadelova, Lubica, Skerenova, Maria, Ivankova, Jela, Lenka, Lisa, Sokol, Juraj, Stasko, Jan

“…Sticky platelet syndrome (SPS) is a disorder with familial occurrence and autosomal dominant trait characterized by platelet hyperaggregability in response to…”
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Association of Genetic Variability in Selected Genes with Platelet Hyperaggregability and Arterial Thrombosis by Brunclikova Monika, Ivankova Jela, Skerenova, Maria, Simurda Tomas, Stanciakova Lucia, Skornova Ingrid, Sterankova Miroslava, Zolkova Jana, Dobrotova Miroslava, Pavol, Holly, Kubisz, Peter, Stasko, Jan

“…Introduction: Inherited platelet hyperaggregability, so called “Sticky platelet syndrome” (SPS), is a prothrombotic platelet disorder. The syndrome contributes…”
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Multimer Analysis of Von Willebrand Factor in Von Willebrand Disease with a Hydrasys Semi-Automatic Analyzer-Single-Center Experience by Skornova, Ingrid, Simurda, Tomas, Stasko, Jan, Zolkova, Jana, Sokol, Juraj, Holly, Pavol, Dobrotova, Miroslava, Plamenova, Ivana, Hudecek, Jan, Brunclikova, Monika, Stryckova, Alena, Kubisz, Peter

“…von Willebrand disease (VWD) is reportedly the most common inherited bleeding disorder. This disorder develops as a result of defects and/or deficiency of the…”
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How Can Rotational Thromboelastometry as a Point-of-Care Method Be Useful for the Management of Secondary Thromboprophylaxis in High-Risk Pregnant Patients? by Stanciakova, Lucia, Dobrotova, Miroslava, Holly, Pavol, Zolkova, Jana, Vadelova, Lubica, Skornova, Ingrid, Ivankova, Jela, Bolek, Tomas, Samos, Matej, Grendar, Marian, Danko, Jan, Kubisz, Peter, Stasko, Jan

“…Thromboprophylaxis with low-molecular-weight heparin (LMWH) for patients with a history of venous thromboembolism (VTE) is suggested. Rotational…”
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High On-Treatment Platelet Reactivity in Patients Undergoing Complex Percutaneous Coronary Interventions by Urban, Lukáš, Ingrid, Škorňová, Žolková, Jana, Ján, Staško, Bolek, Tomáš, Samoš, Matej

“…Patient response to P2Y12 inhibitor therapy is heterogeneous, and those with high on-treatment platelet reactivity (HTPR) are at an increased risk of…”
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Assessing the hemostasis with thromboelastometry in direct oral anticoagulants-treated patients with atrial fibrillation by Korpallová, Barbora, Samoš, Matej, Škorňová, Ingrid, Bolek, Tomáš, Žolková, Jana, Vadelová, Ľubica, Kubisz, Peter, Galajda, Peter, Staško, Ján, Mokáň, Marián

“…•This study tested the ability of ROTEM® to identify changes in hemostasis in a real-world sample of DOACs-treated (dabigatran, rivaroxaban, and…”
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SARS-CoV-2 Infection-Associated Aortic Thrombosis Treated with Oral Factor Xa Inhibition by Strýčková, Alena, Benko, Jakub, Péč, Martin Jozef, Péčová, Monika, Žolková, Jana, Brunclíková, Monika, Bolek, Tomáš, Staško, Ján, Samoš, Matej, Mokáň, Marián

“…Coronavirus disease 2019 (COVID-19) is an acute complex systemic disorder caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).While…”
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Type 2 Diabetes, Atrial Fibrillation, and Direct Oral Anticoagulation by Mokáň, Marián, Kubisz, Peter, Žolková, Jana, Škorňová, Ingrid, Bolek, Tomáš, Samoš, Matej, Prídavková, Dana, Staško, Ján

“…Type 2 diabetes (T2D) is an independent risk factor of stroke and systemic embolism in patients with atrial fibrillation (AF), and T2D patients with…”
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DNA Polymorphisms in Pregnant Women with Sticky Platelet Syndrome by Stančiaková, Lucia, Žolková, Jana, Vadelová, Ľubica, Hornáková, Andrea, Kolková, Zuzana, Vážan, Martin, Dobrotová, Miroslava, Hollý, Pavol, Jedináková, Zuzana, Grendár, Marián, Bolek, Tomáš, Samoš, Matej, Biringer, Kamil, Danko, Ján, Burjanivová, Tatiana, Lasabová, Zora, Kubisz, Peter, Staško, Ján

“…Sticky platelet syndrome (SPS) is a thrombophilia caused by the increased aggregability of platelets in response to the addition of low concentrations of…”
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