Antimicrobial effectiveness of Locacorten-Vioform cream in Secondary infections of common dermatoses

In a double-blind study involving 430 patients, Locacorten (0.02%)-Vioform (3%) cream was found to be highly effective in the treatment of dermatological conditions complicated by secondary bacterial involvement. Themicrobiological conversion and clinical improvement in patients treated with Locacor...

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Bibliographic Details
Published in:	Dermatologica Vol. 151; no. 1; p. 1
Main Authors:	Konopka, E A, Kimble, E F, Zogans, H C, Heyman, H
Format:	Journal Article
Language:	English
Published:	Switzerland 1975
Subjects:	Administration, Topical Arthrodermataceae - isolation & purification Candidiasis, Cutaneous - drug therapy Clinical Trials as Topic Clioquinol - administration & dosage Clioquinol - therapeutic use Drug Resistance, Microbial Drug Therapy, Combination Flumethasone - administration & dosage Flumethasone - therapeutic use Humans Placebos Skin Diseases, Infectious - drug therapy Skin Diseases, Infectious - microbiology Staphylococcal Infections - drug therapy Time Factors
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Summary:	In a double-blind study involving 430 patients, Locacorten (0.02%)-Vioform (3%) cream was found to be highly effective in the treatment of dermatological conditions complicated by secondary bacterial involvement. Themicrobiological conversion and clinical improvement in patients treated with Locacorten-Vioform combinations were markedly greater than those achieved in the groups medicated with (1) Vioform 3%, (2) Locacorten 0.02%, and (3) placebo cream. Staphylococcus aureus was the most prevalent organism isolated from the skin lesions. All strains were sensitive to Vioform, as compared to 62% found to be resistant to other antimicrobials.
ISSN:	0011-9075
DOI:	10.1159/000251292