Search Results - "Zoch, Michéle"
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OMOP CDM Can Facilitate Data-Driven Studies for Cancer Prediction: A Systematic Review
Published in International journal of molecular sciences (05-10-2022)“…The current generation of sequencing technologies has led to significant advances in identifying novel disease-associated mutations and generated large amounts…”
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Assessing the Use of German Claims Data Vocabularies for Research in the Observational Medical Outcomes Partnership Common Data Model: Development and Evaluation Study
Published in JMIR medical informatics (07-11-2023)“…Abstract Background National classifications and terminologies already routinely used for documentation within patient care settings enable the unambiguous…”
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An Extract-Transform-Load Process Design for the Incremental Loading of German Real-World Data Based on FHIR and OMOP CDM: Algorithm Development and Validation
Published in JMIR medical informatics (21-08-2023)“…Abstract Background In the Medical Informatics in Research and Care in University Medicine (MIRACUM) consortium, an IT-based clinical trial recruitment support…”
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An ETL-process design for data harmonization to participate in international research with German real-world data based on FHIR and OMOP CDM
Published in International journal of medical informatics (Shannon, Ireland) (01-01-2023)“…•German CDS is defined in HL7 FHIR for better interoperability across university hospitals.•ETL process was developed using SpringBatch to transform German CDS…”
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Conceptual design of a generic data harmonization process for OMOP common data model
Published in BMC medical informatics and decision making (26-02-2024)“…To gain insight into the real-life care of patients in the healthcare system, data from hospital information systems and insurance systems are required…”
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German Claims Data for Real-World Research: Content Coverage Evaluation in OMOP CDM
Published in Studies in health technology and informatics (18-05-2023)“…Research on real-world data is becoming increasingly important. The current restriction to clinical data in Germany limits the view of the patient. To gain…”
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How to customize common data models for rare diseases: an OMOP-based implementation and lessons learned
Published in Orphanet journal of rare diseases (14-08-2024)“…Given the geographical sparsity of Rare Diseases (RDs), assembling a cohort is often a challenging task. Common data models (CDM) can harmonize disparate…”
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Ten Topics to Get Started in Medical Informatics Research
Published in Journal of medical Internet research (24-07-2023)“…The vast and heterogeneous data being constantly generated in clinics can provide great wealth for patients and research alike. The quickly evolving field of…”
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Secondary use of patient data within decentralized studies using the example of rare diseases in Germany: A data scientist's exploration of process and lessons learned
Published in Digital health (01-01-2024)“…Unlocking the potential of routine medical data for clinical research requires the analysis of data from multiple healthcare institutions. However, according…”
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Predictors of improvement in disease activity in childhood and adolescent Crohn’s disease: an analysis of age, localization, initial severity and drug therapy — data from the Saxon Registry for Inflammatory Bowel Disease in Children in Germany (2000–2014)
Published in European journal of pediatrics (01-10-2024)“…The escalating worldwide prevalence of Crohn’s disease (CD) among children and adolescents, coupled with a trend toward earlier onset, presents significant…”
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A systematic review and meta-regression on international trends in the incidence of ulcerative colitis in children and adolescents associated with socioeconomic and geographic factors
Published in European journal of pediatrics (01-04-2024)“…The incidence of ulcerative colitis (UC) among children and adolescents is rising globally, albeit with notable discrepancies across countries. This systematic…”
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Methods Used in the Development of Common Data Models for Health Data: Scoping Review
Published in JMIR medical informatics (03-08-2023)“…Common data models (CDMs) are essential tools for data harmonization, which can lead to significant improvements in the health domain. CDMs unite data from…”
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Transition database for rare diseases and its use for clinical documentation
Published in Health informatics journal (01-04-2024)“…Patients with rare diseases commonly suffer from severe symptoms as well as chronic and sometimes life-threatening effects. Not only the rarity of the diseases…”
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Interdisciplinary care path and potential IT support for people with rare diseases in Germany
Published in Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen (01-10-2021)“…INTRODUCTIONDue to the high variability and, at the same time, rare occurrence of rare diseases, the diagnosis of these patients (approx. 4 million people in…”
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Interdisziplinärer Versorgungspfad und mögliche IT-Unterstützung für Menschen mit Seltenen Erkrankungen in Deutschland
Published in Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen (01-10-2021)“…Durch die hohe Variabilität bei gleichzeitig rarem Auftreten von Seltenen Erkrankungen, gleicht die Diagnosestellung bei Betroffenen (ca. 4 Millionen Menschen…”
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Towards the Improvement of Clinical Guidelines Based on Real World Data
Published in Studies in health technology and informatics (25-05-2022)“…Computerized clinical guidelines (CCG) are effective instruments for standardizing, monitoring and optimizing medical treatment processes. Nevertheless, due to…”
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Context-Sensitive Common Data Models for Genetic Rare Diseases - A Concept
Published in Studies in health technology and informatics (29-06-2023)“…Current challenges of rare diseases need to involve patients, physicians, and the research community to generate new insights on comprehensive patient cohorts…”
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Development of a Dashboard for Rare Diseases - A Technical Case Report
Published in Studies in health technology and informatics (21-09-2021)“…About 30 million people suffer from a rare disease in Europe. Those affected face a variety of problems. These include the lack of information and difficult…”
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