Search Results - "Zoładek, Teresa"

The role of Rsp5 ubiquitin ligase in regulation of diverse processes in yeast cells by Kaliszewski, Paweł, Zoładek, Teresa

“…Rsp5 is a conserved ubiquitin ligase involved in regulation of numerous cellular processes. A growing number of publications describing new functions of the…”
Get full text

Human hAtg2A protein expressed in yeast is recruited to preautophagosomal structure but does not complement autophagy defects of atg2Δ strain by Romanyuk, Daria, Polak, Anna, Maleszewska, Agnieszka, Sieńko, Marzena, Grynberg, Marcin, Żołądek, Teresa

“…Yeast Atg2, an autophagy-related protein, is highly conserved in other fungi and has two homologues in humans, one of which is hAtg2A encoded by the…”
Get full text

Rsp5p ubiquitin ligase and the transcriptional activators Spt23p and Mga2p are involved in co-regulation of biosynthesis of end products of the mevalonate pathway and triacylglycerol in yeast Saccharomyces cerevisiae by Kaliszewski, Paweł, Szkopińska, Anna, Ferreira, Thierry, Świezewska, Ewa, Berges, Thierry, Zołądek, Teresa

“…Rsp5p, a yeast S. cerevisiae ubiquitin ligase, is essential for regulation of unsaturated fatty acid synthesis via activation of the transcriptional activators…”
Get full text

Yeast Models and Molecular Mechanisms of Neurodegenerative Diseases 2.0 by Kaminska, Joanna, Zoladek, Teresa

“…One of the goals of human genetics is to discover the variants that contribute to human diseases [...]…”
Get full text

Nedd4, a human ubiquitin ligase, affects actin cytoskeleton in yeast cells by Stawiecka-Mirota, Marta, Kamińska, Joanna, Urban-Grimal, Daniele, Haines, Dale S., Żołądek, Teresa

“…Human Nedd4 ubiquitin ligase is involved in protein trafficking, signal transduction and oncogenesis. Nedd4 with an inactive WW4 domain is toxic to yeast…”
Get full text

Yeast Models and Molecular Mechanisms of Neurodegenerative Diseases by Kaminska, Joanna, Zoladek, Teresa

“…Neurodegenerative diseases are a group of age-related diseases and a growing problem in an aging society [...]…”
Get full text

The binding of the APT1 domains to phosphoinositides is regulated by metal ions in vitro by Kolakowski, Damian, Kaminska, Joanna, Zoladek, Teresa

“…Chorein is a protein of the Vps13 family, and defects in this protein cause the rare neurodegenerative disorder chorea-acanthocytosis (ChAc). Chorein is…”
Get full text

Yeast as a Model to Find New Drugs and Drug Targets for VPS13 -Dependent Neurodegenerative Diseases by Kaminska, Joanna, Soczewka, Piotr, Rzepnikowska, Weronika, Zoladek, Teresa

“…Mutations in human genes result in rare neurological diseases, including chorea-acanthocytosis. The pathogenesis of these diseases is poorly understood, and no…”
Get full text

The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus by Kolakowski, Damian, Rzepnikowska, Weronika, Kaniak-Golik, Aneta, Zoladek, Teresa, Kaminska, Joanna

“…VPS13 proteins are evolutionarily conserved. Mutations in the four human genes ( ) encoding VPS13A-D proteins are linked to developmental or neurodegenerative…”
Get full text

Partial Inhibition of Calcineurin Activity by Rcn2 as a Potential Remedy for Vps13 Deficiency by Wardaszka, Patrycja, Soczewka, Piotr, Sienko, Marzena, Zoladek, Teresa, Kaminska, Joanna

“…Regulation of calcineurin, a Ca /calmodulin-regulated phosphatase, is important for the nervous system, and its abnormal activity is associated with various…”
Get full text

Amino acid substitution equivalent to human chorea-acanthocytosis I2771R in yeast Vps13 protein affects its binding to phosphatidylinositol 3-phosphate by Rzepnikowska, Weronika, Flis, Krzysztof, Kaminska, Joanna, Grynberg, Marcin, Urbanek, Agnieszka, Ayscough, Kathryn R, Zoladek, Teresa

“…The rare human disorder chorea-acanthocytosis (ChAc) is caused by mutations in hVPS13A gene. The hVps13A protein interacts with actin and regulates the level…”
Get full text

Yeast and other lower eukaryotic organisms for studies of Vps13 proteins in health and disease by Rzepnikowska, Weronika, Flis, Krzysztof, Muñoz‐Braceras, Sandra, Menezes, Regina, Escalante, Ricardo, Zoladek, Teresa

“…Human Vps13 proteins are associated with several diseases, including the neurodegenerative disorder Chorea‐acanthocytosis (ChAc), yet the biology of these…”
Get full text

Mutation in a new gene MAF1 affects tRNA suppressor efficiency in Saccharomyces cerevisiae by Boguta, Magdalena, Czerska, Kamila, Żołądek, Teresa

“…Mutation in the MAF1 gene was identified in a screen for decreased efficiency of tRNA suppressor SUP11 in the yeast Saccharomyces cerevisiae ( Sc). maf1-1…”
Get full text

Targeting Copper Homeostasis Improves Functioning of vps13 Δ Yeast Mutant Cells, a Model of VPS13 -Related Diseases by Soczewka, Piotr, Tribouillard-Tanvier, Déborah, di Rago, Jean-Paul, Zoladek, Teresa, Kaminska, Joanna

“…Ion homeostasis is crucial for organism functioning, and its alterations may cause diseases. For example, copper insufficiency and overload are associated with…”
Get full text

Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae by Anaul Kabir, M., Kaminska, Joanna, Segel, George B., Bethlendy, Gabor, Lin, Paul, Della Seta, Flavio, Blegen, Casey, Swiderek, Kristine M., Żołądek, Teresa, Arndt, Kim T., Sherman, Fred

“…Eukaryotic chaperonins, the Cct complexes, are assembled into two rings, each of which is composed of a stoichiometric array of eight different subunits, which…”
Get full text

Molecular Basis of the Pathogenic Mechanism Induced by the m.9191T>C Mutation in Mitochondrial ATP6 Gene by Su, Xin, Dautant, Alain, Godard, François, Bouhier, Marine, Zoladek, Teresa, Kucharczyk, Roza, di Rago, Jean-Paul, Tribouillard-Tanvier, Déborah

“…Probing the pathogenicity and functional consequences of mitochondrial DNA (mtDNA) mutations from patient's cells and tissues is difficult due to genetic…”
Get full text

Yeast-model-based study identified myosin- and calcium-dependent calmodulin signalling as a potential target for drug intervention in chorea-acanthocytosis by Soczewka, Piotr, Kolakowski, Damian, Smaczynska-de Rooij, Iwona, Rzepnikowska, Weronika, Ayscough, Kathryn R, Kaminska, Joanna, Zoladek, Teresa

“…Chorea-acanthocytosis (ChAc) is a rare neurodegenerative disease associated with mutations in the human gene. The mechanism of ChAc pathogenesis is unclear. A…”
Get full text

Functional analysis of the human orthologue of the RSP5-encoded ubiquitin protein ligase, hNedd4, in yeast by Gajewska, Beata, Shcherbik, Natalia, Oficjalska, Danuta, Haines, Dale S, Zoładek, Teresa

“…hNedd4 and Rsp5p are orthologous ubiquitin ligases that contain a catalytic Hect domain, a C2 domain and multiple WW domains that mediate interactions with…”
Get full text

Rsp5 ubiquitin ligase affects isoprenoid pathway and cell wall organization in S. cerevisiae by Kamińska, Joanna, Kwapisz, Marta, Grabińska, Kariona, Orłowski, Jacek, Boguta, Magdalena, Palamarczyk, Grazyna, Zoładek, Teresa

“…Dimethylallyl diphosphate, an isomer of isopentenyl diphosphate, is a common substrate of Mod5p, a tRNA modifying enzyme, and the farnesyl diphosphate synthase…”
Get full text

Rsp5p, a New Link between the Actin Cytoskeleton and Endocytosis in the Yeast Saccharomyces cerevisiae by Kamińska, Joanna, Gajewska, Beata, Hopper, Anita K., ˙Zołądek, Teresa

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text