Search Results - "Zmurchok, Cole"

Biophysical Models of PAR Cluster Transport by Cortical Flow in C. elegans Early Embryogenesis by Zmurchok, Cole, Holmes, William R.

“…The clustering of membrane-bound proteins facilitates their transport by cortical actin flow in early Caenorhabditis elegans embryo cell polarity. PAR-3…”
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Direction-dependent interaction rules enrich pattern formation in an individual-based model of collective behavior by Zmurchok, Cole, de Vries, Gerda

“…Direction-dependent interaction rules are incorporated into a one-dimensional discrete-time stochastic individual-based model (IBM) of collective behavior to…”
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Making drugs from T cells: The quantitative pharmacology of engineered T cell therapeutics by Kirouac, Daniel C., Zmurchok, Cole, Morris, Denise

“…Engineered T cells have emerged as highly effective treatments for hematological cancers. Hundreds of clinical programs are underway in efforts to expand the…”
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Correction To: Application of Quasi-Steady-State Methods to Nonlinear Models of Intracellular Transport by Molecular Motors by Zmurchok, Cole, Small, Tim, Ward, Michael J., Edelstein-Keshet, Leah

“…We apologize for the error in the references…”
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Polarization and migration in the zebrafish posterior lateral line system by Knutsdottir, Hildur, Zmurchok, Cole, Bhaskar, Dhananjay, Palsson, Eirikur, Dalle Nogare, Damian, Chitnis, Ajay B, Edelstein-Keshet, Leah

“…Collective cell migration plays an important role in development. Here, we study the posterior lateral line primordium (PLLP) a group of about 100 cells,…”
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Moth Mating: Modeling Female Pheromone Calling and Male Navigational Strategies to Optimize Reproductive Success by Stepien, Tracy L., Zmurchok, Cole, Hengenius, James B., Caja Rivera, Rocío Marilyn, D’Orsogna, Maria R., Lindsay, Alan E.

“…Male and female moths communicate in complex ways to search for and to select a mate. In a process termed calling, females emit small quantities of pheromones,…”
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240 Presentation of DLL4 and VCAM on paramagnetic beads replicates thymic Notch signaling and enables differentiation of functional of iPSC derived TCR T-cells in vitro by Chandrasekaran, Siddarth, Kardel, Melanie, Martinez, Elisa, Zeidan, Nabil, Deyati, Avisek, Wall, Valerie, Lee, Dylan, Farahani, Negin, AuYeung, Amanda, Subedar, Omar, Cadell, Michael, Apelu, Sommer, Prochazka, Laura, Sahaf, Zahra, Duong, Angela, Zmurchok, Cole, Yoon, Boyoung, Kirouac, Dan, Belew, Muluken, Mann, Jasdeep, Rajesh, Deepika, Bond, Chris

“…BackgroundAdoptive TCR T-cell therapies from autologous donor are expensive, time-consuming and depends on quality of T-cells in patients. One of the key…”
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Coupling mechanical tension and GTPase signaling to generate cell and tissue dynamics by Zmurchok, Cole, Bhaskar, Dhananjay, Edelstein-Keshet, Leah

“…Regulators of the actin cytoskeleton such Rho GTPases can modulate forces developed in cells by promoting actomyosin contraction. At the same time, through…”
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Simple Rho GTPase Dynamics Generate a Complex Regulatory Landscape Associated with Cell Shape by Zmurchok, Cole, Holmes, William R.

“…Migratory cells exhibit a variety of morphologically distinct responses to their environments that manifest in their cell shape. Some protrude uniformly to…”
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Membrane Tension Can Enhance Adaptation to Maintain Polarity of Migrating Cells by Zmurchok, Cole, Collette, Jared, Rajagopal, Vijay, Holmes, William R.

“…Migratory cells are known to adapt to environments that contain wide-ranging levels of chemoattractant. Although biochemical models of adaptation have been…”
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Deconvolution of clinical variance in CAR-T cell pharmacology and response by Kirouac, Daniel C., Zmurchok, Cole, Deyati, Avisek, Sicherman, Jordan, Bond, Chris, Zandstra, Peter W.

“…Chimeric antigen receptor T cell (CAR-T) expansion and persistence vary widely among patients and predict both efficacy and toxicity. However, the mechanisms…”
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Author Correction: Deconvolution of clinical variance in CAR-T cell pharmacology and response by Kirouac, Daniel C., Zmurchok, Cole, Deyati, Avisek, Sicherman, Jordan, Bond, Chris, Zandstra, Peter W.

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Local and Global Bifurcations in a Mechanochemical ODE Model for Cell Behavior by Zmurchok, Cole, Sahota, Matthew, Nagata, Wayne, Cytrynbaum, Eric N

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Application of Quasi-Steady-State Methods to Nonlinear Models of Intracellular Transport by Molecular Motors by Zmurchok, Cole, Small, Tim, Ward, Michael J., Edelstein-Keshet, Leah

“…Molecular motors such as kinesin and dynein are responsible for transporting material along microtubule networks in cells. In many contexts, motor dynamics can…”
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