Search Results - "Zlabinger, G. J."

A Comprehensive and Quantitative Analysis of the Major Specificities in Rabbit Antithymocyte Globulin Preparations by Popow, I., Leitner, J., Grabmeier‐Pfistershammer, K., Majdic, O., Zlabinger, G.‐J., Kundi, M., Steinberger, P.

“…Antithymocyte globulin (ATG) preparations are used for treatment and prevention of graft rejection episodes, graft versus host disease and aplastic anemia. The…”
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Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production by Zeyda, M, Farmer, D, Todoric, J, Aszmann, O, Speiser, M, Gyori, G, Zlabinger, G.J, Stulnig, T.M

“…Objective: Obesity is associated with a chronic low-grade inflammation and an increased abundance of macrophages in adipose tissue. Adipose tissue macrophages…”
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Blocking antibodies induced by allergen‐specific immunotherapy ameliorate allergic airway disease in a human/mouse chimeric model by Vizzardelli, C., Gindl, M., Roos, S., Möbs, C., Nagl, B., Zimmann, F., Sexl, V., Kenner, L., Neunkirchner, A., Zlabinger, G. J., Pickl, W. F., Pfützner, W., Bohle, B.

“…Background Allergen‐specific immunotherapy (AIT) induces specific blocking antibodies (Ab), which are claimed to prevent IgE‐mediated reactions to allergens…”
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CMV Late Phase‐Induced mTOR Activation Is Essential for Efficient Virus Replication in Polarized Human Macrophages by Poglitsch, M., Weichhart, T., Hecking, M., Werzowa, J., Katholnig, K., Antlanger, M., Krmpotic, A., Jonjic, S., Hörl, W. H., Zlabinger, G. J., Puchhammer, E., Säemann, M. D.

“…Human cytomegalovirus (CMV) remains one of the most important pathogens following solid‐organ transplantation. Mounting evidence indicates that mammalian…”
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Human blood basophils do not act as antigen-presenting cells for the major birch pollen allergen Bet v 1 by Kitzmüller, C., Nagl, B., Deifl, S., Walterskirchen, C., Jahn-Schmid, B., Zlabinger, G. J., Bohle, B.

“…Background: Several studies in mice have recently shown that basophils can act as antigen‐presenting cells (APC) inducing Th2‐mediated immune responses against…”
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A hypoallergenic variant of the major birch pollen allergen shows distinct characteristics in antigen processing and T-cell activation by Kitzmüller, C., Wallner, M., Deifl, S., Mutschlechner, S., Walterskirchen, C., Zlabinger, G. J., Ferreira, F., Bohle, B.

“…Background BM4 is a novel genetically engineered variant of the major birch pollen allergen Bet v 1 that lacks the typical Bet v 1‐like fold and displays…”
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Tamm-Horsfall protein: a multilayered defence molecule against urinary tract infection by Säemann, M. D., Weichhart, T., Hörl, W. H., Zlabinger, G. J.

“…Urinary tract infection (UTI) is the most common nonepidemic bacterial infection in humans, representing a constant danger for the host. Both innate and…”
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Anti‐inflammatory effects of sodium butyrate on human monocytes: potent inhibition of IL‐12 and up‐regulation of IL‐10 production by Säemann, Marcus D., Böhmig, Georg A., Österreicher, Christoph H., Burtscher, Helmut, Parolini, Ornella, Diakos, Christos, Stöckl, Johannes, Hörl, Walter H., Zlabinger, Gerhard J.

“…ABSTRACT Cytokines are critical in regulating unresponsiveness versus immunity towards enteric antigens derived from the intestinal flora and ingested food…”
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Danon disease: Case report and detection of new mutation by Regelsberger, G., Höftberger, R., Pickl, W. F., Zlabinger, G. J., Körmöczi, U., Salzer-Muhar, U., Luckner, D., Bodamer, O. A., Mayr, J. A., Muss, W. H., Budka, H., Bernheimer, H.

“…Summary Danon disease is an X-linked disorder resulting from mutations in the lysosome-associated membrane protein-2 ( LAMP2 ) gene. We report a male patient…”
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Characterization of the T‐cell response to Dau c 1, the Bet v 1‐homolog in carrot by Zulehner, N., Nagl, B., Briza, P., Roulias, A., Ballmer‐Weber, B., Zlabinger, G. J., Ferreira, F., Bohle, B.

“…Background In contrast to other Bet v 1‐related food allergens, the major carrot allergen, Dau c 1, has been suggested to induce food allergy independently…”
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Differential activation of dendritic cells by toll‐like receptors causes diverse differentiation of naïve CD4+ T cells from allergic patients by Deifl, S., Kitzmüller, C., Steinberger, P., Himly, M., Jahn‐Schmid, B., Fischer, G. F., Zlabinger, G. J., Bohle, B.

“…Background To avert the differentiation of allergen‐specific Th2 cells in atopic individuals is a major goal in the prevention and therapy of IgE‐mediated…”
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A microplate assay for the detection of oxidative products using 2',7'-dichlorofluorescin-diacetate by Rosenkranz, A R, Schmaldienst, S, Stuhlmeier, K M, Chen, W, Knapp, W, Zlabinger, G J

“…A fluorometric microplate assay was established for the detection of respiratory burst activity in phagocytic cells by assessing oxidation of…”
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CD40 triggered human monocyte-derived dendritic cells convert to tolerogenic dendritic cells when JAK3 activity is inhibited by Säemann, M.D, Kelemen, P, Zeyda, M, Böhmig, G, Staffler, G, Zlabinger, G.J

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n‐Butyrate downregulates the stimulatory function of peripheral blood‐derived antigen‐presenting cells: a potential mechanism for modulating T‐cell responses by short‐chain fatty acids by BÖHMIG, G. A., KRIEGER, P‐M., SÄEMANN, M. D., WENHARDT, C., POHANKA, E., ZLABINGER, G. J.

“…Modulation of proliferative T‐cell responses by n‐butyrate has been suggested to result from direct interference with cell cycle progression. Considering the…”
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Characterization of CDw92 as a Member of the Choline Transporter-Like Protein Family Regulated Specifically on Dendritic Cells by Wille, Stefan, Szekeres, Andreas, Majdic, Otto, Prager, Elisabeth, Staffler, Gunther, Stockl, Johannes, Kunthalert, Duangkamol, Prieschl, Eva E, Baumruker, Thomas, Burtscher, Helmut, Zlabinger, Gerhard J, Knapp, Walter, Stockinger, Hannes

“…CDw92 is a 70-kDa surface protein broadly expressed on leukocytes and endothelial cells. In this manuscript, we present the molecular cloning of the CDw92…”
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Role of humoral immune reactions as target for antirejection therapy in recipients of a spousal-donor kidney graft by Böhmig, Georg A., Regele, Heinz, Säemann, Marcus D., Exner, Markus, Druml, Wilfred, Kovarik, Josef, Hörl, Walter H., Zlabinger, Gerhard J., Watschinger, Bruno

“…Excellent graft outcome has been reported for spousal-donor kidney transplantation. In husband-to-wife transplantation, however, a tendency toward inferior…”
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Reactive oxygen product formation by human neutrophils as an early marker for biocompatibility of dialysis membranes by ROSENKRANZ, A R., TEMPL, E., TRAINDL, O., HEINZL, H., ZLABINGER, G. J.

“…SUMMARY Production of reactive oxygen intermediates (ROI) by neutrophils (PMN) in vivo was examined by a whole blood assay using dichlorofluorescein‐diacetate…”
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Induction of Hyporesponsiveness and Impaired T Lymphocyte Activation by the CD31 Receptor:Ligand Pathway in T Cells by Prager, Elisabeth, Staffler, Gunther, Majdic, Otto, Saemann, Marcus D, Godar, Samuel, Zlabinger, Gerhard J, Stockinger, Hannes

“…CD31 is a member of the Ig superfamily expressed on various cell types of the vasculature, including a certain subpopulation of T lymphocytes. Previous reports…”
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Targeting the ERK-1/2 signalling pathway results in alloantigen-specific anergy in human t cells by Krieger, P.-M, Säemann, M.D, Böhmig, G.A, Mühlbacher, F, Zlabinger, G.J

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Serum Proteins Modified by Neutrophil-Derived Oxidants as Mediators of Neutrophil Stimulation by Kormoczi, Gunther F, Wolfel, Ulrike M, Rosenkranz, Alexander R, Horl, Walter H, Oberbauer, Rainer, Zlabinger, Gerhard J

“…Reactive oxygen intermediates (ROI) released during inflammation may act as important mediators of neutrophil effector functions. The objective of this…”
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