Search Results - "Zivadinov, R."

Substantia Nigra Free Water Increases Longitudinally in Parkinson Disease by Guttuso, Jr, T, Bergsland, N, Hagemeier, J, Lichter, D G, Pasternak, O, Zivadinov, R

“…Free water in the posterior substantia nigra obtained from a bi-tensor diffusion MR imaging model has been shown to significantly increase over 1- and 4-year…”
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Leptomeningeal Contrast Enhancement Is Related to Focal Cortical Thinning in Relapsing-Remitting Multiple Sclerosis: A Cross-Sectional MRI Study by Bergsland, N, Ramasamy, D, Tavazzi, E, Hojnacki, D, Weinstock-Guttman, B, Zivadinov, R

“…Leptomeningeal inflammation is associated with the development of global cortical gray matter atrophy in multiple sclerosis. However, its association with…”
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Hypertension and heart disease are associated with development of brain atrophy in multiple sclerosis: a 5‐year longitudinal study by Jakimovski, D., Gandhi, S., Paunkoski, I., Bergsland, N., Hagemeier, J., Ramasamy, D. P., Hojnacki, D., Kolb, C., Benedict, R. H. B., Weinstock‐Guttman, B., Zivadinov, R.

“…Background Cardiovascular diseases (CVDs) are more frequent in multiple sclerosis (MS) patients when compared to controls. In particular, CVDs are linked with…”
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Subcortical atrophy is associated with cognitive impairment in mild Parkinson disease: a combined investigation of volumetric changes, cortical thickness, and vertex-based shape analysis by Mak, E, Bergsland, N, Dwyer, M G, Zivadinov, R, Kandiah, N

“…The involvement of subcortical deep gray matter and cortical thinning associated with mild Parkinson disease remains poorly understood. We assessed cortical…”
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Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis by ZIVADINOV, R, REDER, A. T, FILIPPI, M, MINAGAR, A, STÜVE, O, LASSMANN, H, RACKE, M. K, DWYER, M. G, FROHMAN, E. M, KHAN, O

“…Disease-modifying agents (DMAs), including interferon beta (IFNbeta) and glatiramer acetate (GA), are the mainstays of long-term treatment of multiple…”
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Cholesterol and neurodegeneration: longitudinal changes in serum cholesterol biomarkers are associated with new lesions and gray matter atrophy in multiple sclerosis over 5 years of follow‐up by Murali, N., Browne, R. W., Fellows Maxwell, K., Bodziak, M. L., Jakimovski, D., Hagemeier, J., Bergsland, N., Weinstock‐Guttman, B., Zivadinov, R., Ramanathan, M.

“…Background and purpose Cholesterol is an important structural component of myelin and essential for brain homeostasis. Our objective was to investigate whether…”
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Subcortical and Cortical Gray Matter Atrophy in a Large Sample of Patients with Clinically Isolated Syndrome and Early Relapsing-Remitting Multiple Sclerosis by BERGSLAND, N, HORAKOVA, D, DWYER, M. G, DOLEZAL, O, SEIDL, Z. K, VANECKOVA, M, KRASENSKY, J, HAVRDOVA, E, ZIVADINOV, R

“…Recent studies have shown that selective regional, but not global, GM atrophy occurs from clinical onset to conversion to clinically definite MS. Our aim was…”
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Evaluation of Leptomeningeal Contrast Enhancement Using Pre-and Postcontrast Subtraction 3D-FLAIR Imaging in Multiple Sclerosis by Zivadinov, R, Ramasamy, D P, Hagemeier, J, Kolb, C, Bergsland, N, Schweser, F, Dwyer, M G, Weinstock-Guttman, B, Hojnacki, D

“…Leptomeningeal contrast enhancement is found in patients with multiple sclerosis, though reported rates have varied. The use of 3D-fluid-attenuated inversion…”
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Impact of Focal White Matter Damage on Localized Subcortical Gray Matter Atrophy in Multiple Sclerosis: A 5-Year Study by Fuchs, T A, Carolus, K, Benedict, R H B, Bergsland, N, Ramasamy, D, Jakimovski, D, Weinstock-Guttman, B, Kuceyeski, A, Zivadinov, R, Dwyer, M G

“…It is unclear to what extent subcortical gray matter atrophy is a primary process as opposed to a result of focal white matter damage. Correlations between WM…”
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Brain Atrophy Is Associated with Disability Progression in Patients with MS followed in a Clinical Routine by Ghione, E, Bergsland, N, Dwyer, M G, Hagemeier, J, Jakimovski, D, Paunkoski, I, Ramasamy, D P, Silva, D, Carl, E, Hojnacki, D, Kolb, C, Weinstock-Guttman, B, Zivadinov, R

“…The assessment of brain atrophy in a clinical routine is not performed routinely in multiple sclerosis. Our aim was to determine the feasibility of brain…”
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Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS by ZIVADINOV, R, MARR, K, HUNT, K, ANDREWS, M, CARL, E, DWYER, M. G, HOJNACKI, D, WEINSTOCK-GUTTMAN, B, CUTTER, G, RAMANATHAN, M, BENEDICT, R. H. B, KENNEDY, C, ELFADIL, M, YEH, A. E, REUTHER, J, BROOKS, C

“…Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in patients with multiple sclerosis (MS). A subject is considered CCSVI positive if ≥…”
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Lower Arterial Cross-Sectional Area of Carotid and Vertebral Arteries and Higher Frequency of Secondary Neck Vessels Are Associated with Multiple Sclerosis by Belov, P, Jakimovski, D, Krawiecki, J, Magnano, C, Hagemeier, J, Pelizzari, L, Weinstock-Guttman, B, Zivadinov, R

“…Arterial and neck vessel system characteristics of patients with multiple sclerosis have not been previously investigated. Therefore, the aim of this study was…”
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Memory impairment in multiple sclerosis: correlation with deep grey matter and mesial temporal atrophy by Benedict, R H B, Ramasamy, D, Munschauer, F, Weinstock-Guttman, B, Zivadinov, R

“…Background:MRI research in multiple sclerosis (MS) samples reveals pathology in both the cerebral cortex and deep grey matter (DGM). The classical subcortical…”
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Disability Improvement Is Associated with Less Brain Atrophy Development in Multiple Sclerosis by Ghione, E, Bergsland, N, Dwyer, M G, Hagemeier, J, Jakimovski, D, Ramasamy, D P, Hojnacki, D, Lizarraga, A A, Kolb, C, Eckert, S, Weinstock-Guttman, B, Zivadinov, R

“…It is unknown whether deceleration of brain atrophy is associated with disability improvement in patients with MS. Our aim was to investigate whether patients…”
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A Serial 10-Year Follow-Up Study of Atrophied Brain Lesion Volume and Disability Progression in Patients with Relapsing-Remitting MS by Zivadinov, R, Horakova, D, Bergsland, N, Hagemeier, J, Ramasamy, D P, Uher, T, Vaneckova, M, Havrdova, E, Dwyer, M G

“…Disappearance of T2 lesions into CSF spaces is frequently observed in patients with MS. Our aim was to investigate temporal changes of cumulative atrophied…”
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Five-Year Longitudinal Study of Neck Vessel Cross-Sectional Area in Multiple Sclerosis by Pelizzari, L, Jakimovski, D, Laganà, M M, Bergsland, N, Hagemeier, J, Baselli, G, Weinstock-Guttman, B, Zivadinov, R

“…Alterations of neck vessel cross-sectional area in multiple sclerosis have been reported. Our aim was to investigate the evolution of the neck vessel…”
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Smoking is associated with increased lesion volumes and brain atrophy in multiple sclerosis by ZIVADINOV, R, WEINSTOCK-GUTTMAN, B, HASHMI, K, ABDELRAHMAN, N, STOSIC, M, DWYER, M, HUSSEIN, S, DURFEE, J, RAMANATHAN, M

“…Cigarette smoking has been linked to higher susceptibility and increased risk of progressive multiple sclerosis (MS). The effects of smoking on MRI…”
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Evolution of cortical and thalamus atrophy and disability progression in early relapsing-remitting MS during 5 years by Zivadinov, R, Bergsland, N, Dolezal, O, Hussein, S, Seidl, Z, Dwyer, M G, Vaneckova, M, Krasensky, J, Potts, J A, Kalincik, T, Havrdová, E, Horáková, D

“…Pathologic changes in GM have an important role in MS. We investigated the association between SDGM and cortical volume changes and disability progression in…”
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Neurolymphatic biomarkers of brain endothelial inflammatory activation: Implications for multiple sclerosis diagnosis by Yun, J.W., Cvek, U., Kilgore, P.C.S.R., Tsunoda, I., Omura, S., Sato, F., Zivadinov, R., Ramanathan, M., Minagar, A., Alexander, J.S.

“…Multiple sclerosis (MS) is the leading cause of non-traumatic neurological disability in young adults, and its diagnosis is often delayed due to the lack of…”
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Conventional and advanced imaging in neuromyelitis optica by Barnett, Y, Sutton, I J, Ghadiri, M, Masters, L, Zivadinov, R, Barnett, M H

“…Myelitis and optic neuritis are prototypic clinical presentations of both multiple sclerosis and neuromyelitis optica. Once considered a subtype of multiple…”
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