Search Results - "Ziv, Ravit"

In vivo anti-MUC1+ tumor activity and sequences of high-affinity anti-MUC1-SEA antibodies by Pichinuk, Edward, Chalik, Michael, Benhar, Itai, Ginat-Koton, Ravit, Ziv, Ravit, Smorodinsky, Nechama I., Haran, Gabi, Garbar, Christian, Bensussan, Armand, Meeker, Alan, Guillaume, Thierry, Rubinstein, Daniel B., Wreschner, Daniel H.

“…Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies…”
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MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA by Chalick, Michael, Jacobi, Oded, Pichinuk, Edward, Garbar, Christian, Bensussan, Armand, Meeker, Alan, Ziv, Ravit, Zehavi, Tania, Smorodinsky, Nechama I, Hilkens, John, Hanisch, Franz-Georg, Rubinstein, Daniel B, Wreschner, Daniel H

“…Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The…”
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The MUC1 SEA Module Is a Self-cleaving Domain by Levitin, Fiana, Stern, Omer, Weiss, Mordechai, Gil-Henn, Chava, Ziv, Ravit, Prokocimer, Zofnat, Smorodinsky, Nechama I., Rubinstein, Daniel B., Wreschner, Daniel H.

“…MUC1, a glycoprotein overexpressed by a variety of human adenocarcinomas, is a type I transmembrane protein (MUC1/TM) that soon after its synthesis undergoes…”
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PATE Gene Clusters Code for Multiple, Secreted TFP/Ly-6/uPAR Proteins That Are Expressed in Reproductive and Neuron-rich Tissues and Possess Neuromodulatory Activity by Levitin, Fiana, Weiss, Mordechai, Hahn, Yoonsoo, Stern, Omer, Papke, Roger L., Matusik, Robert, Nandana, Srinivas R., Ziv, Ravit, Pichinuk, Edward, Salame, Sharbel, Bera, Tapan, Vincent, James, Lee, Byungkook, Pastan, Ira, Wreschner, Daniel H.

“…We report here syntenic loci in humans and mice incorporating gene clusters coding for secreted proteins each comprising 10 cysteine residues. These conform to…”
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Generation of ligand‐receptor alliances by “SEA” module‐mediated cleavage of membrane‐associated mucin proteins by Wreschner, Daniel H., McGuckin, Michael A., Williams, Stefanie J., Baruch, Amos, Yoeli, Merav, Ziv, Ravit, Okun, Liron, Zaretsky, Joseph, Smorodinsky, Nechama, Keydar, Iafa, Neophytou, Pavlos, Stacey, Martin, Lin, His‐Hsien, Gordon, Siamon

“…A mechanism is described whereby one and the same gene can encode both a receptor protein as well as its specific ligand. Generation of this receptor–ligand…”
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A Novel Protein Derived from the MUC1 Gene by Alternative Splicing and Frameshifting by Levitin, Fiana, Baruch, Amos, Weiss, Mordechai, Stiegman, Keren, Hartmann, Mor-li, Yoeli-Lerner, Merav, Ziv, Ravit, Zrihan-Licht, Sheila, Shina, Sima, Gat, Andrea, Lifschitz, Beatrice, Simha, Moshe, Stadler, Yona, Cholostoy, Alina, Gil, Benny, Greaves, David, Keydar, Iafa, Zaretsky, Joseph, Smorodinsky, Nechama, Wreschner, Daniel H.

“…Genes that have been designated the name “MUC” code for proteins comprising mucin domains. These proteins may be involved in barrier and protective functions…”
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Antibody Targeting of Cell-Bound MUC1 SEA Domain Kills Tumor Cells by PICHINUK, Edward, BENHAR, Itai, WRESCHNER, Daniel H, JACOBI, Oded, CHALIK, Michael, WEISS, Lotem, ZIV, Ravit, SYMPSON, Carolyn, KARWA, Amolkumar, SMORODINSKY, Nechama I, RUBINSTEIN, Daniel B

“…The cell-surface glycoprotein MUC1 is a particularly appealing target for antibody targeting, being selectively overexpressed in many types of cancers and a…”
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Targeting of tumor cells and tumor stem cells by antibodies specific for the cell-bound alpha/beta junction of MUC1 by Pichinuk, Edward, Benhar, Itai, Jacobi, Oded, Ziv, Ravit, Smorodinsky, Nechama, Rubinstein, Daniel B., Wreschner, Daniel H.

“…Abstract only e13018 Background: MUC1 is a glycoprotein over-expressed on the cell surface of a variety of malignancies and has long been a subject of interest…”
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LY6S, a New IFN-Inducible Human Member of the Ly6a Subfamily Expressed by Spleen Cells and Associated with Inflammation and Viral Resistance by Shmerling, Moriya, Chalik, Michael, Smorodinsky, Nechama I, Meeker, Alan, Roy, Sujayita, Sagi-Assif, Orit, Meshel, Tsipi, Danilevsky, Artem, Shomron, Noam, Levinger, Shmuel, Nishry, Bar, Baruchi, David, Shargorodsky, Avital, Ziv, Ravit, Sarusi-Portuguez, Avital, Lahav, Maoz, Ehrlich, Marcelo, Braschi, Bryony, Bruford, Elspeth, Witz, Isaac P, Wreschner, Daniel H

“…Syntenic genomic loci on human chromosome 8 and mouse chromosome 15 (mChr15) code for LY6/Ly6 (lymphocyte Ag 6) family proteins. The 23 murine family genes…”
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The MUC1 oncoprotein as a functional target: Immunotoxin binding to α/β junction mediates cell killing by Rubinstein, Daniel B., Karmely, Maya, Pichinuk, Edward, Ziv, Ravit, Benhar, Itai, Feng, Ningping, Smorodinsky, Nechama I., Wreschner, Daniel H.

“…MUC1, a heavily glycosylated mucin, has generated considerable interest as a target for tumor killing because of its overexpression in malignancies…”
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MUC1/X protein immunization enhances cDNA immunization in generating anti-MUC1 alpha/beta junction antibodies that target malignant cells by Rubinstein, Daniel B, Karmely, Maya, Ziv, Ravit, Benhar, Itai, Leitner, Orit, Baron, Shoshana, Katz, Ben-Zion, Wreschner, Daniel H

“…MUC1 has generated considerable interest as a tumor marker and potential target for tumor killing. To date, most antibodies against MUC1 recognize epitopes…”
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MUC1/X Protein Immunization Enhances cDNA Immunization in Generating Anti-MUC1 alpha /{beta} Junction Antibodies that Target Malignant Cells by Rubinstein, Daniel B, Karmely, Maya, Ziv, Ravit, Benhar, Itai, Leitner, Orit, Baron, Shoshana, Katz, Ben-Zion, Wreschner, Daniel H

“…MUC1 has generated considerable interest as a tumor marker and potential target for tumor killing. To date, most antibodies against MUC1 recognize epitopes…”
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MUC1/X protein immunization enhances cDNA immunization in generating anti-MUd α/β junction antibodies that target malignant cells by RUBINSTEIN, Daniel B, KARMELY, Maya, ZIV, Ravit, BENHAR, Itai, LEITNER, Orit, BARON, Shoshana, KATZ, Ben-Zion, WRESCHNER, Daniel H

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