Search Results - "Zitnik, Galynn"

Structural and functional characterization of a novel FE65 protein product up-regulated in cognitively impaired FE65 knockout mice by Cool, Bethany H, Zitnik, Galynn, Martin, George M, Hu, Qubai

“…FE65 is a multi-modular adaptor protein that binds the cytoplasmic tail of the β-amyloid precursor protein (APP). Genetic evidence suggests that APP is…”
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The Locus Control Region Is Necessary for Gene Expression in the Human β-Globin Locus but Not the Maintenance of an Open Chromatin Structure in Erythroid Cells by Reik, Andreas, Telling, Agnes, Zitnik, Galynn, Cimbora, Daniel, Epner, Elliot, Groudine, Mark

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Abeta 1-40 Enhances the Proliferation of Human Diploid Fibroblasts by Theda, Lindsey, Drews, Michelle K., Zitnik, Galynn, Oshima, Junko, Martin, George M.

“…There is a vast literature on the role of beta amyloid (Aβ) peptides in the pathogenesis of Alzheimer’s disease. There is a paucity of research, however, on…”
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Aβ 1–40 enhances the proliferation of human diploid fibroblasts by Theda, Lindsey, Drews, Michelle K, Zitnik, Galynn, Oshima, Junko, Martin, George M

“…Abstract There is a vast literature on the role of beta amyloid (Aβ) peptides in the pathogenesis of Alzheimer's disease. However, there is a paucity of…”
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X-ray induced cataract is preceded by LEC loss, and coincident with accumulation of cortical DNA, and ROS; similarities with age-related cataracts by Pendergrass, William, Zitnik, Galynn, Tsai, Ryan, Wolf, Norman

“…To compare age-related cataractous (ARC) changes in unirradiated mice lenses to those induced by head-only X-irradiation of 3 month-old mice. lens epithelial…”
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DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations by Saha, Bidisha, Zitnik, Galynn, Johnson, Simon, Nguyen, Quyen, Risques, Rosa A, Martin, George M, Oshima, Junko

“…Segmental progeroid syndromes are groups of disorders with multiple features suggestive of accelerated aging. One subset of adult-onset progeroid syndromes,…”
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Age-related retention of fiber cell nuclei and nuclear fragments in the lens cortices of multiple species by Pendergrass, William, Zitnik, Galynn, Urfer, Silvan R, Wolf, Norman

“…To determine the differences between species in the retention of lens fiber cell nuclei and nuclear fragments in the aging lens cortex and the relationship of…”
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Age-related decline in neurogenesis: Old cells or old environment? by Zitnik, Galynn, Martin, George M.

“…As the baby boom generation ages, the numbers of patients afflicted with various age-related pathologies of the brain will increase, creating a tremendous…”
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Endoproteolytic Cleavage of FE65 Converts the Adaptor Protein to a Potent Suppressor of the sAPPα Pathway in Primates by Hu, Qubai, Wang, Lin, Yang, Zheng, Cool, Bethany H., Zitnik, Galynn, Martin, George M.

“…Adaptor protein FE65 (APBB1) specifically binds to the intracellular tail of the type I transmembrane protein, β-amyloid precursor protein (APP). The formation…”
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Localizations of endogenous APP/APP-proteolytic products are consistent with microtubular transport by Zitnik, Galynn, Wang, Lin, Martin, George M, Hu, Qubai

“…Dementia of the Alzheimer type (DAT) is associated with the accumulation of beta-amyloid (A beta) peptides derived from beta-amyloid precursor protein (APP)…”
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Endoproteolytic cleavage of FE65 converts the adaptor protein to a potent suppressor of the sAPPalpha pathway in primates by Hu, Qubai, Wang, Lin, Yang, Zheng, Cool, Bethany H, Zitnik, Galynn, Martin, George M

“…Adaptor protein FE65 (APBB1) specifically binds to the intracellular tail of the type I transmembrane protein, beta-amyloid precursor protein (APP). The…”
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Endoproteolytic Cleavage of FE65 Converts the Adaptor Protein to a Potent Suppressor of the sAPPα Pathway in Primates by Qubai Hu, Lin Wang, Zheng Yang, Bethany H. Cool, Galynn Zitnik, George M. Martin

“…Adaptor protein FE65 (APBB1) specifically binds to the intracellular tail of the type I transmembrane protein, β-amyloid precursor protein (APP). The…”
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Use of Yeast Artificial Chromosomes (YACs) for Studying Control of Gene Expression: Correct Regulation of the Genes of a Human β-Globin Locus YAC Following Transfer to Mouse Erythroleukemia Cell Lines by Peterson, Kenneth R., Zitnik, Galynn, Huxley, Clare, Lowrey, Christopher H., Gnirke, Andreas, Leppig, Kathleen A., Papayannopoulou, Thalia, Stamatoyannopoulos, George

“…We demonstrate that transfer of a yeast artificial chromosome (YAC) containing 230 kb of the human β-globin locus into mouse erythroleukemia cells by fusion…”
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Corrections: Use of Yeast Artificial Chromosomes (YACs) for Studying Control of Gene Expression: Correct Regulation of the Genes of a Human β-Globin Locus YAC Following Transfer to Mouse Erythroleukemia Cell Lines by Peterson, Kenneth R., Zitnik, Galynn, Huxley, Clare, Lowrey, Christopher H., Gnirke, Andreas, Leppig, Kathleen A., Papayannopoulou, Thalia, Stamatoyannopoulos, George

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Murine Erythroleukemia Cell Line GM979 Contains Factors that Can Activate Silent Chromosomal Human γ-Globin Genes by Zitnik, Galynn, Hines, Pamela, Stamatoyannopoulos, George, Papayannopoulou, Thalia

“…We introduced a normal chromosome 11 into GM979 murine erythroleukemia cells by fusing them with Epstein-Barr virus-transformed lymphocytes from a normal…”
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Effects of thyroid hormones on cardiac hypertrophy and beta-adrenergic receptors during aging by Zitnik, G, Roth, G S

“…Administration of thyroxine daily at a dosage of 6.4 mu g/g body weight stimulates cardiac hypertrophy in both 9--13-month-old (mature, n = 34) and…”
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