Search Results - "Zisi, A"

Small molecule-mediated disruption of ribosome biogenesis synergizes with FGFR inhibitors to suppress glioma cell growth by Zisi, Asimina, Kanellis, Dimitris C, Moussaud, Simon, Karlsson, Ida, Carén, Helena, Bräutigam, Lars, Bartek, Jiri, Lindström, Mikael S

“…Abstract Background High-grade gliomas are malignant brain tumors characterized by aggressiveness and resistance to chemotherapy. Prognosis remains dismal,…”
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Iodine-lithium-alpha-dextrin (ILαD) against Staphylococcus aureus skin infections: a comparative study of in-vitro bactericidal activity and cytotoxicity between ILαD and povidone-iodine by Zisi, A.P., Exindari, M.K., Siska, E.K., Koliakos, G.G.

“…As antimicrobial resistance continues to increase, revisiting old antimicrobial agents, modified to enhance efficacy and safety, becomes important. Iodine has…”
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Dense deposit disease in an adolescent male mimicking acute post-streptococcal glomerulonephritis by Siomou, E, Liapis, G, Zisi, A, Csuka, D, Prohászka, Z

“…Dense deposit disease (DDD), a subtype of complement factor 3 glomerulopathy (C3G), is a rare entity associated with dysregulation of the alternative…”
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The antimalarial drug amodiaquine stabilizes p53 through ribosome biogenesis stress, independently of its autophagy-inhibitory activity by Espinoza, Jaime A., Zisi, Asimina, Kanellis, Dimitris C., Carreras-Puigvert, Jordi, Henriksson, Martin, Hühn, Daniela, Watanabe, Kenji, Helleday, Thomas, Lindström, Mikael S., Bartek, Jiri

“…Pharmacological inhibition of ribosome biogenesis is a promising avenue for cancer therapy. Herein, we report a novel activity of the FDA-approved antimalarial…”
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Targeting Ribosome Biogenesis in Cancer: Lessons Learned and Way Forward by Zisi, Asimina, Bartek, Jiri, Lindström, Mikael S

“…Rapid growth and unrestrained proliferation is a hallmark of many cancers. To accomplish this, cancer cells re-wire and increase their biosynthetic and…”
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Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET by Kanellis, Dimitris C., Zisi, Asimina, Skrott, Zdenek, Lemmens, Bennie, Espinoza, Jaime A., Kosar, Martin, Björkman, Andrea, Li, Xuexin, Arampatzis, Stefanos, Bartkova, Jirina, Andújar-Sánchez, Miguel, Fernandez-Capetillo, Oscar, Mistrik, Martin, Lindström, Mikael S., Bartek, Jiri

“…Drug repurposing is a versatile strategy to improve current therapies. Disulfiram has long been used in the treatment of alcohol dependency and multiple…”
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The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output by Kanellis, Dimitris C, Espinoza, Jaime A, Zisi, Asimina, Sakkas, Elpidoforos, Bartkova, Jirina, Katsori, Anna-Maria, Boström, Johan, Dyrskjøt, Lars, Broholm, Helle, Altun, Mikael, Elsässer, Simon J, Lindström, Mikael S, Bartek, Jiri

“…Eukaryotic initiation factor 4A-III (eIF4A3), a core helicase component of the exon junction complex, is essential for splicing, mRNA trafficking, and…”
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