Search Results - "Zinsmeister, AR"

The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patients by Colombel, Jean-Frederic, Loftus, Jr, Edward V, Tremaine, William J, Egan, Laurence J, Harmsen, W Scott, Schleck, Cathy D, Zinsmeister, Alan R, Sandborn, William J

“…The aim of this study was to evaluate the short- and long-term safety of infliximab in patients with Crohn's disease in clinical practice. The medical records…”
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Correlation of C‐reactive protein with clinical, endoscopic, histologic, and radiographic activity in inflammatory bowel disease by Solem, Craig A, Loftus, Edward V, Tremaine, William J, Harmsen, William S, Zinsmeister, Alan R, Sandborn, William J

“…Introduction: We sought to examine the relationship between C‐reactive protein (CRP) and clinical, endoscopic, histologic, and radiographic activity in…”
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A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating by Kim, H. J., Vazquez Roque, M. I., Camilleri, M., Stephens, D., Burton, D. D., Baxter, K., Thomforde, G., Zinsmeister, A. R.

“…Aim:  To evaluate the effects of a combination probiotic on symptoms and colonic transit in patients with irritable bowel syndrome (IBS) and significant…”
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Lower functional gastrointestinal disorders: evidence of abnormal colonic transit in a 287 patient cohort by Manabe, N., Wong, B. S., Camilleri, M., Burton, D., Mckinzie, S., Zinsmeister, A. R.

“…Background  Abnormalities of colonic motility were reported in relatively small studies of patients with lower functional gastrointestinal disorders (FGID)…”
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Familial aggregation of irritable bowel syndrome: a prospective study by Kalantar, J S, Locke, G R, Zinsmeister, A R, Beighley, C M, Talley, N J

“…Background: Patients with irritable bowel syndrome (IBS) often report family members with similar symptoms, but family studies are lacking. We hypothesised…”
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Risk factors for chronic constipation and a possible role of analgesics by Chang, J. Y., Locke, G. Richard, Schleck, C. D., Zinsmeister, A. R., Talley, N. J.

“…Constipation has an estimated prevalence of 15% in the general population. However, the etiopathogenesis of this condition remains relatively obscure. This…”
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Familial association in adults with functional gastrointestinal disorders by Locke, 3rd, G R, Zinsmeister, A R, Talley, N J, Fett, S L, Melton, 3rd, L J

“…To evaluate the association between functional gastrointestinal (GI) symptoms and a family history of abdominal pain or bowel problems. A valid self-report…”
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Effects of a kappa-opioid agonist, asimadoline, on satiation and GI motor and sensory functions in humans by Delgado-Aros, Silvia, Chial, Heather J, Camilleri, Michael, Szarka, Lawrence A, Weber, Frank T, Jacob, Jutta, Ferber, Irene, McKinzie, Sanna, Burton, Duane D, Zinsmeister, Alan R

“…To compare the effects of the kappa-opioid agonist asimadoline and placebo on visceral sensation and gastrointestinal (GI) motor functions in humans, 91…”
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Effect of a κ‐opioid agonist, i.v. JNJ‐38488502, on sensation of colonic distensions in healthy male volunteers by Floyd, B. N., Camilleri, M., Busciglio, I., Sweetser, S., Burton, D., Wong, G. Y., Kell, S., Khanna, S., Hwang, S., Zinsmeister, A. R.

“…Kappa‐opioid receptors are located on visceral pain fibres. JNJ‐38488502 is a highly selective tetrapeptide κ‐opioid agonist with little access to the central…”
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Epidemiology of colonic symptoms and the irritable bowel syndrome by Talley, N J, Zinsmeister, A R, Van Dyke, C, Melton, 3rd, L J

“…Functional gastrointestinal disease is believed to be very common, but reports of its prevalence have not usually evaluated random community samples, and…”
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Risk factors for chronic diarrhoea in the community in the absence of irritable bowel syndrome by Chang, J. Y., Richard Locke Iii, G., Schleck, C. D., Zinsmeister, A. R., Talley, N. J.

“…In contrast to irritable bowel syndrome (IBS), the prevalence and risk factors for diarrhoea in the absence of IBS in the community are unknown. We aimed to…”
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Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota by Locke, GR, Talley, NJ, Fett, SL, Zinsmeister, AR, Melton, LJ

“…BACKGROUND & AIMS: Gastroesophageal reflux is considered a common condition, but detailed population-based data on reflux in the United States are lacking. The…”
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A Controlled Trial of Gluten-Free Diet in Patients With Irritable Bowel Syndrome-Diarrhea: Effects on Bowel Frequency and Intestinal Function by Vazquez–Roque, Maria I, Camilleri, Michael, Smyrk, Thomas, Murray, Joseph A, Marietta, Eric, O'Neill, Jessica, Carlson, Paula, Lamsam, Jesse, Janzow, Denise, Eckert, Deborah, Burton, Duane, Zinsmeister, Alan R

“…Background & Aims Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) could benefit from a gluten-free diet (GFD). Methods We performed a…”
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Risk Factors Associated With Progression to Intestinal Complications of Crohn's Disease in a Population-Based Cohort by Thia, Kelvin T, Sandborn, William J, Harmsen, William S, Zinsmeister, Alan R, Loftus, Edward V

“…Background And Aims We sought to assess the evolution of Crohn's disease behavior in an American population-based cohort. Methods Medical records of all…”
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Increasing incidence of celiac disease in a North American population by Ludvigsson, Jonas F, Rubio-Tapia, Alberto, van Dyke, Carol T, Melton, 3rd, L Joseph, Zinsmeister, Alan R, Lahr, Brian D, Murray, Joseph A

“…The prevalence of celiac disease (CD) varies greatly, potentially because of incomplete ascertainment of cases and small study samples with limited statistical…”
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Randomised clinical trial: pregabalin vs placebo for irritable bowel syndrome by Saito, Yuri A., Almazar, Ann E., Tilkes, Katherine E., Choung, Rok Seon, Van Norstrand, Michael D., Schleck, Cathy D., Zinsmeister, Alan R., Talley, Nicholas J.

“…Summary Background Pregabalin is a calcium channel α2δ ligand that modifies visceral hypersensitivity in IBS patients. Clinical data for pregabalin in IBS are…”
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Duodenal mastocytosis, eosinophilia and intraepithelial lymphocytosis as possible disease markers in the irritable bowel syndrome and functional dyspepsia by WALKER, M. M., TALLEY, N. J., PRABHAKAR, M., PENNANEAC’H, C. J., ARO, P., RONKAINEN, J., STORSKRUBB, T., HARMSEN, W. S., ZINSMEISTER, A. R., AGREUS, L.

“…Summary Background  Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common functional disorders without defined pathology. Mast cells and…”
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Prospective Study of Motor, Sensory, Psychologic, and Autonomic Functions in Patients With Irritable Bowel Syndrome by Camilleri, Michael, McKinzie, Sanna, Busciglio, Irene, Low, Phillip A, Sweetser, Seth, Burton, Duane, Baxter, Kari, Ryks, Michael, Zinsmeister, Alan R

“…Background & Aims: The aim of this study was to assess pathophysiology in irritable bowel syndrome (IBS). Methods: A total of 122 IBS patients (3 male) and 41…”
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PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis by Loftus, E V, Harewood, G C, Loftus, C G, Tremaine, W J, Harmsen, W S, Zinsmeister, A R, Jewell, D A, Sandborn, W J

“…Background: Inflammatory bowel disease associated with primary sclerosing cholangitis (PSC-IBD) may have a high prevalence of rectal sparing, backwash ileitis,…”
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Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients With Nonconstipated Irritable Bowel Syndrome by Wong, Banny S, Camilleri, Michael, Busciglio, Irene, Carlson, Paula, Szarka, Lawrence A, Burton, Duane, Zinsmeister, Alan R

“…Background & Aims Cannabinoid receptors are located on cholinergic neurons. Genetic variants that affect endocannabinoid metabolism are associated with colonic…”
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