Search Results - "Zink, Jeffrey I."

Taking the Temperature of the Interiors of Magnetically Heated Nanoparticles by Dong, Juyao, Zink, Jeffrey I

“…The temperature increase inside mesoporous silica nanoparticles induced by encapsulated smaller superparamagnetic nanocrystals in an oscillating magnetic field…”
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Nanovalve-Controlled Cargo Release Activated by Plasmonic Heating by Croissant, Jonas, Zink, Jeffrey I

“…The synthesis and operation of a light-operated nanovalve that controls the pore openings of mesoporous silica nanoparticles containing gold nanoparticle cores…”
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Nanomachines and Other Caps on Mesoporous Silica Nanoparticles for Drug Delivery by Chen, Wei, Glackin, Carlotta A, Horwitz, Marcus A, Zink, Jeffrey I

“…Conspectus Mesoporous silica nanoparticles (MSNs) are delivery vehicles that can carry cargo molecules and release them on command. The particles used in the…”
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Spatial, Temporal, and Dose Control of Drug Delivery using Noninvasive Magnetic Stimulation by Chen, Wei, Cheng, Chi-An, Zink, Jeffrey I

“…Noninvasive stimuli-responsive drug delivery using magnetic fields in conjunction with superparamagnetic nanoparticles offers the potential for the spatial and…”
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Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals by Lu, Jie, Liong, Monty, Li, Zongxi, Zink, Jeffrey I., Tamanoi, Fuyuhiko

“…Mesoporous silica nanoparticles (MSNs) are a promising material for drug delivery. In this Full Paper, MSNs are first shown to be well tolerated, as…”
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Probing the Local Nanoscale Heating Mechanism of a Magnetic Core in Mesoporous Silica Drug-Delivery Nanoparticles Using Fluorescence Depolarization by Lin, Fang-Chu, Zink, Jeffrey I

“…In the presence of an alternating magnetic field (AMF), a superparamagnetic iron oxide nanoparticle (SPION) generates heat. Understanding the local heating…”
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Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications by Croissant, Jonas G., Butler, Kimberly S., Zink, Jeffrey I., Brinker, C. Jeffrey

“…Natural silica and silicates are predominantly crystalline and constitute the most abundant components of the Earth’s crust. Man-made silica is typically…”
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Engineered Design of Mesoporous Silica Nanoparticles to Deliver Doxorubicin and P-Glycoprotein siRNA to Overcome Drug Resistance in a Cancer Cell Line by Meng, Huan, Liong, Monty, Xia, Tian, Li, Zongxi, Ji, Zhaoxia, Zink, Jeffrey I, Nel, Andre E

“…Overexpression of drug efflux transporters such as P-glycoprotein (Pgp) protein is one of the major mechanisms for multiple drug resistance (MDR) in cancer…”
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Codelivery of an Optimal Drug/siRNA Combination Using Mesoporous Silica Nanoparticles To Overcome Drug Resistance in Breast Cancer in Vitro and in Vivo by Meng, Huan, Mai, Wilson X, Zhang, Haiyuan, Xue, Min, Xia, Tian, Lin, Sijie, Wang, Xiang, Zhao, Yang, Ji, Zhaoxia, Zink, Jeffrey I, Nel, Andre E

“…We used a multifunctional mesoporous silica nanoparticle (MSNP) carrier to overcome doxorubicin (Dox) resistance in a multidrug resistant (MDR) human breast…”
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Toxicity Mechanisms in Escherichia coli Vary for Silver Nanoparticles and Differ from Ionic Silver by Ivask, Angela, ElBadawy, Amro, Kaweeteerawat, Chitrada, Boren, David, Fischer, Heidi, Ji, Zhaoxia, Chang, Chong Hyun, Liu, Rong, Tolaymat, Thabet, Telesca, Donatello, Zink, Jeffrey I, Cohen, Yoram, Holden, Patricia Ann, Godwin, Hilary A

“…Silver nanoparticles (Ag NPs) are commonly added to various consumer products and materials to impair bacterial growth. Recent studies suggested that the…”
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Mechanized Silica Nanoparticles: A New Frontier in Theranostic Nanomedicine by Ambrogio, Michael W, Thomas, Courtney R, Zhao, Yan-Li, Zink, Jeffrey I, Stoddart, J. Fraser

“…Medicine can benefit significantly from advances in nanotechnology because nanoscale assemblies promise to improve on previously established therapeutic and…”
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Light-Activated Nanoimpeller-Controlled Drug Release in Cancer Cells by Lu, Jie, Choi, Eunshil, Tamanoi, Fuyuhiko, Zink, Jeffrey I.

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Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties by Xia, Tian, Kovochich, Michael, Liong, Monty, Mädler, Lutz, Gilbert, Benjamin, Shi, Haibin, Yeh, Joanne I, Zink, Jeffrey I, Nel, Andre E

“…Nanomaterials (NM) exhibit novel physicochemical properties that determine their interaction with biological substrates and processes. Three metal oxide…”
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Use of Size and a Copolymer Design Feature To Improve the Biodistribution and the Enhanced Permeability and Retention Effect of Doxorubicin-Loaded Mesoporous Silica Nanoparticles in a Murine Xenograft Tumor Model by Meng, Huan, Xue, Min, Xia, Tian, Ji, Zhaoxia, Tarn, Derrick Y, Zink, Jeffrey I, Nel, Andre E

“…A key challenge for improving the efficacy of passive drug delivery to tumor sites by a nanocarrier is to limit reticuloendothelial system uptake and to…”
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Autonomous in Vitro Anticancer Drug Release from Mesoporous Silica Nanoparticles by pH-Sensitive Nanovalves by Meng, Huan, Xue, Min, Xia, Tian, Zhao, Yan-Li, Tamanoi, Fuyuhiko, Stoddart, J. Fraser, Zink, Jeffrey I, Nel, Andre E

“…Mesoporous silica nanoparticles (MSNP) have proven to be an extremely effective solid support for controlled drug delivery on account of the fact that their…”
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Polyethyleneimine Coating Enhances the Cellular Uptake of Mesoporous Silica Nanoparticles and Allows Safe Delivery of siRNA and DNA Constructs by Xia, Tian, Kovochich, Michael, Liong, Monty, Meng, Huan, Kabehie, Sanaz, George, Saji, Zink, Jeffrey I, Nel, Andre E

“…Surface-functionalized mesoporous silica nanoparticles (MSNP) can be used as an efficient and safe carrier for bioactive molecules. In order to make the MSNP a…”
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Use of Metal Oxide Nanoparticle Band Gap To Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation by Zhang, Haiyuan, Ji, Zhaoxia, Xia, Tian, Meng, Huan, Low-Kam, Cecile, Liu, Rong, Pokhrel, Suman, Lin, Sijie, Wang, Xiang, Liao, Yu-Pei, Wang, Meiying, Li, Linjiang, Rallo, Robert, Damoiseaux, Robert, Telesca, Donatello, Mädler, Lutz, Cohen, Yoram, Zink, Jeffrey I, Nel, Andre E

“…We demonstrate for 24 metal oxide (MOx) nanoparticles that it is possible to use conduction band energy levels to delineate their toxicological potential at…”
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Designed Synthesis of CeO2 Nanorods and Nanowires for Studying Toxicological Effects of High Aspect Ratio Nanomaterials by Ji, Zhaoxia, Wang, Xiang, Zhang, Haiyuan, Lin, Sijie, Meng, Huan, Sun, Bingbing, George, Saji, Xia, Tian, Nel, André E, Zink, Jeffrey I

“…While it has been shown that high aspect ratio nanomaterials like carbon nanotubes and TiO2 nanowires can induce toxicity by acting as fiber-like substances…”
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Multifunctional Inorganic Nanoparticles for Imaging, Targeting, and Drug Delivery by Liong, Monty, Lu, Jie, Kovochich, Michael, Xia, Tian, Ruehm, Stefan G, Nel, Andre E, Tamanoi, Fuyuhiko, Zink, Jeffrey I

“…Drug delivery, magnetic resonance and fluorescence imaging, magnetic manipulation, and cell targeting are simultaneously possible using a multifunctional…”
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Protein-gold clusters-capped mesoporous silica nanoparticles for high drug loading, autonomous gemcitabine/doxorubicin co-delivery, and in-vivo tumor imaging by Croissant, Jonas G., Zhang, Dingyuan, Alsaiari, Shahad, Lu, Jie, Deng, Lin, Tamanoi, Fuyuhiko, AlMalik, Abdulaziz M., Zink, Jeffrey I., Khashab, Niveen M.

“…Functional nanocarriers capable of transporting high drug contents without premature leakage and to controllably deliver several drugs are needed for better…”
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