Search Results - "Zindl, Carlene L"

Refine Results
  1. 1

    Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis by Harbour, Stacey N., Maynard, Craig L., Zindl, Carlene L., Schoeb, Trenton R., Weaver, Casey T.

    “…Th17 cells reactive to the enteric microbiota are central to the pathogenesis of certain types of inflammatory bowel disease. However, Th17 cells display…”
    Get full text
    Journal Article
  2. 2

    IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis by Zindl, Carlene L., Lai, Jen-Feng, Lee, Yun Kyung, Maynard, Craig L., Harbour, Stacey N., Ouyang, Wenjun, Chaplin, David D., Weaver, Casey T.

    “…IL-22 plays an important role in mucosal epithelial cell homeostasis. Using a dextran sodium sulfate-induced mouse model of acute colitis, we observed an…”
    Get full text
    Journal Article
  3. 3

    Tumor Immune Evasion by Zindl, Carlene L., Chaplin, David D.

    “…Malignant cells can induce the formation of lymphoid tissue–like structures that help the tumor evade host immunity. Many types of human tumors can suppress…”
    Get full text
    Journal Article
  4. 4

    Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae by Lai, Jen-Feng, Zindl, Carlene L, Duffy, Lynn B, Atkinson, T Prescott, Jung, Yong Woo, van Rooijen, Nico, Waites, Ken B, Krause, Duncan C, Chaplin, David D

    Published in PloS one (23-12-2010)
    “…Mycoplasma pneumoniae (Mp), a common cause of pneumonia, is associated with asthma; however, the mechanisms underlying this association remain unclear. We…”
    Get full text
    Journal Article
  5. 5
  6. 6

    Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis by Singer, Jeffrey R., Blosser, Emily G., Zindl, Carlene L., Silberger, Daniel J., Conlan, Sean, Laufer, Vincent A., DiToro, Daniel, Deming, Clay, Kumar, Ranjit, Morrow, Casey D., Segre, Julia A., Gray, Michael J., Randolph, David A., Weaver, Casey T.

    Published in Nature medicine (01-11-2019)
    “…Late-onset sepsis (LOS) is thought to result from systemic spread of commensal microbes from the intestines of premature infants. Clinical use of probiotics…”
    Get full text
    Journal Article
  7. 7

    Distal colonocytes targeted by C. rodentium recruit T-cell help for barrier defence by Zindl, Carlene L., Wilson, C. Garrett, Chadha, Awalpreet S., Duck, Lennard W., Cai, Baiyi, Harbour, Stacey N., Nagaoka-Kamata, Yoshiko, Hatton, Robin D., Gao, Min, Figge, David A., Weaver, Casey T.

    Published in Nature (London) (16-05-2024)
    “…Interleukin 22 (IL-22) has a non-redundant role in immune defence of the intestinal barrier 1 – 3 . T cells, but not innate lymphoid cells, have an…”
    Get full text
    Journal Article
  8. 8

    Regulatory T cells expressing interleukin 10 develop from Foxp3 + and Foxp3 − precursor cells in the absence of interleukin 10 by Oliver, James R, Weaver, Casey T, Janowski, Karen M, Rudensky, Alexander Y, Maynard, Craig L, Harrington, Laurie E, Zindl, Carlene L

    Published in Nature immunology (01-09-2007)
    “…CD4(+) regulatory T cells (T(reg) cells) that produce interleukin 10 (IL-10) are important contributors to immune homeostasis. We generated mice with a…”
    Get full text
    Journal Article
  9. 9

    IL-1R signaling promotes STAT3 and NF-κB factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription by Whitley, Sarah K., Balasubramani, Anand, Zindl, Carlene L., Sen, Ranjan, Shibata, Yoichiro, Crawford, Gregory E., Weathington, Nathaniel M., Hatton, Robin D., Weaver, Casey T.

    Published in The Journal of biological chemistry (12-10-2018)
    “…Interleukin (IL)-1β plays a critical role in IL-6β– and transforming growth factor β (TGFβ)–initiated Th17 differentiation and induction of Th17-mediated…”
    Get full text
    Journal Article
  10. 10
  11. 11

    Taking Control of Follicular Dendritic Cells by Chaplin, David D., Zindl, Carlene L.

    Published in Immunity (Cambridge, Mass.) (2006)
    “…Follicular dendritic cells signal the formation of B cell follicles as well as B cell activation, proliferation, and maturation. However, the precise molecular…”
    Get full text
    Journal Article
  12. 12

    IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell–iTreg cell balance by Basu, Rajatava, Whitley, Sarah K, Bhaumik, Suniti, Zindl, Carlene L, Schoeb, Trenton R, Benveniste, Etty N, Pear, Warren S, Hatton, Robin D, Weaver, Casey T

    Published in Nature immunology (01-03-2015)
    “…iT reg cells and T H 17 cells share developmental steps, but their cellular fate depends on environmental cues. Weaver and colleagues show that IL-1 signaling…”
    Get full text
    Journal Article
  13. 13

    The Lymphotoxin LTα1β2 Controls Postnatal and Adult Spleen Marginal Sinus Vascular Structure and Function by Zindl, Carlene L., Kim, Tea Hyun, Zeng, Meiqin, Archambault, Angela S., Grayson, Mitchell H., Choi, Kyunghee, Schreiber, Robert D., Chaplin, David D.

    Published in Immunity (Cambridge, Mass.) (20-03-2009)
    “…The lymphotoxin LTα 1 β 2 supports the development and maintenance of several aspects of spleen structure, but its significance for marginal sinus (MS)…”
    Get full text
    Journal Article
  14. 14

    T H 17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity by Harbour, Stacey N, DiToro, Daniel F, Witte, Steven J, Zindl, Carlene L, Gao, Min, Schoeb, Trenton R, Jones, Gareth W, Jones, Simon A, Hatton, Robin D, Weaver, Casey T

    Published in Science immunology (17-07-2020)
    “…Acting in concert with TGF-β, interleukin-6 (IL-6) signaling induces T helper 17 (T 17) cell development by programming T 17-related genes via signal…”
    Get more information
    Journal Article
  15. 15

    MMP induced by Gr-1⁺ cells are crucial for recruitment of Th cells into the airways by Jung, Yong Woo, Zindl, Carlene L, Lai, Jen-Feng, Weaver, Casey T, Chaplin, David D

    Published in European journal of immunology (01-08-2009)
    “…Th2 lymphocytes deliver essential signals for induction of asthmatic airway inflammation. We previously found that airway antigen challenge induces recruitment…”
    Get full text
    Journal Article
  16. 16

    Induction of a late asthmatic response associated with airway inflammation in mice by Nabe, Takeshi, Zindl, Carlene L., Jung, Yong Woo, Stephens, Robin, Sakamoto, Akari, Kohno, Shigekatsu, Atkinson, T. Prescott, Chaplin, David D.

    Published in European journal of pharmacology (03-10-2005)
    “…To investigate mechanisms underlying the late asthmatic response, we developed a murine model using repetitive intratracheal antigen challenge. BALB/c mice…”
    Get full text
    Journal Article
  17. 17

    Citrobacter rodentium: a model enteropathogen for understanding the interplay of innate and adaptive components of type 3 immunity by Silberger, D J, Zindl, C L, Weaver, C T

    Published in Mucosal immunology (01-09-2017)
    “…Citrobacter rodentium is a natural murine intestinal pathogen that shares a core set of virulence factors with the related human pathogens enteropathogenic…”
    Get full text
    Journal Article
  18. 18

    Temporal changes in cellular sources of CXC chemokines control neutrophil recruitment during Citrobacter rodentium infection by Cai, Baiyi, Zindl, Carlene L., Silberger, Daniel J., Figge, David A., Singer, Jeffery R., Merz, Simon F, Gunzer, Matthias, Weaver, Casey T.

    Published in The Journal of immunology (1950) (01-05-2020)
    “…Enteropathogenic E. coli (EPEC) is one of the leading causes of diarrheal disease among children. Citrobacter rodentium (C.r) is a mouse model for EPEC and…”
    Get full text
    Journal Article
  19. 19
  20. 20