Search Results - "Zimmermann, S."

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites by Gerbe, François, Sidot, Emmanuelle, Smyth, Danielle J., Ohmoto, Makoto, Matsumoto, Ichiro, Dardalhon, Valérie, Cesses, Pierre, Garnier, Laure, Pouzolles, Marie, Brulin, Bénédicte, Bruschi, Marco, Harcus, Yvonne, Zimmermann, Valérie S., Taylor, Naomi, Maizels, Rick M., Jay, Philippe

“…Epithelial tuft cells secretion of IL-25 is shown to regulate type 2 epithelial responses to helminth parasite infection via an IL-13/IL-4Rα-dependent feedback…”
Get full text

Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells by Bornstein, Chamutal, Nevo, Shir, Giladi, Amir, Kadouri, Noam, Pouzolles, Marie, Gerbe, François, David, Eyal, Machado, Alice, Chuprin, Anna, Tóth, Beáta, Goldberg, Ori, Itzkovitz, Shalev, Taylor, Naomi, Jay, Philippe, Zimmermann, Valérie S., Abramson, Jakub, Amit, Ido

“…T cell development and selection are coordinated in the thymus by a specialized niche of diverse stromal populations 1 – 3 . Although much progress has been…”
Get full text

One- and Two-Pole Compensation of Charge- Sensitive Amplifiers With Resistive Feedback to Improve the Energy Resolution in GRETA by Stezelberger, T., Zimmermann, S.

“…The gamma-ray energy tracking array (GRETA) is a detector system currently under construction in the USA. The energy of the gamma ray is measured in real time…”
Get full text

Glucose and Glutamine Metabolism Regulate Human Hematopoietic Stem Cell Lineage Specification by Oburoglu, Leal, Tardito, Saverio, Fritz, Vanessa, de Barros, Stéphanie C., Merida, Peggy, Craveiro, Marco, Mamede, João, Cretenet, Gaspard, Mongellaz, Cédric, An, Xiuli, Klysz, Dorota, Touhami, Jawida, Boyer-Clavel, Myriam, Battini, Jean-Luc, Dardalhon, Valérie, Zimmermann, Valérie S., Mohandas, Narla, Gottlieb, Eyal, Sitbon, Marc, Kinet, Sandrina, Taylor, Naomi

“…The metabolic state of quiescent hematopoietic stem cells (HSCs) is an important regulator of self-renewal, but it is unclear whether or how metabolic…”
Get full text

Clinical Proof of Concept for a Novel Hepatocyte-Targeting GalNAc-siRNA Conjugate by Zimmermann, Tracy S., Karsten, Verena, Chan, Amy, Chiesa, Joseph, Boyce, Malcolm, Bettencourt, Brian R., Hutabarat, Renta, Nochur, Saraswathy, Vaishnaw, Akshay, Gollob, Jared

“…Advancement of RNAi-based therapeutics depends on effective delivery to the site of protein synthesis. Although intravenously administered, multi-component…”
Get full text

Adverse reactions to injectable soft tissue fillers by Requena, Luis, MD, Requena, Celia, MD, Christensen, Lise, MD, Zimmermann, Ute S., MD, Kutzner, Heinz, MD, Cerroni, Lorenzo, MD

“…In recent years, injections with filler agents are often used for wrinkle-treatment and soft tissue augmentation by dermatologists and plastic surgeons…”
Get full text

Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis by Dafni, U, Michielin, O, Lluesma, S Martin, Tsourti, Z, Polydoropoulou, V, Karlis, D, Besser, M J, Haanen, J, Svane, I -M, Ohashi, P S, Kammula, U S, Orcurto, A, Zimmermann, S, Trueb, L, Klebanoff, C A, Lotze, M T, Kandalaft, L E, Coukos, G

“…Adoptive cell therapy (ACT) using autologous tumor-infiltrating lymphocytes (TIL) has been tested in advanced melanoma patients at various centers. We…”
Get full text

The Medial Orbitofrontal Cortex Regulates Sensitivity to Outcome Value by Gourley, Shannon L, Zimmermann, Kelsey S, Allen, Amanda G, Taylor, Jane R

“…An essential component of goal-directed decision-making is the ability to maintain flexible responding based on the value of a given reward, or "reinforcer."…”
Get full text

Potassium and sodium transport in non-animal cells: the Trk/Ktr/HKT transporter family by Corratgé-Faillie, C, Jabnoune, M, Zimmermann, S, Véry, A.-A, Fizames, C, Sentenac, H

“…Bacterial Trk and Ktr, fungal Trk and plant HKT form a family of membrane transporters permeable to K⁺ and/or Na⁺ and characterized by a common structure…”
Get full text

Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients by Ishii, Kazusa, Pouzolles, Marie, Chien, Christopher D, Erwin-Cohen, Rebecca A, Kohler, M Eric, Qin, Haiying, Lei, Haiyan, Kuhn, Skyler, Ombrello, Amanda K, Dulau-Florea, Alina, Eckhaus, Michael A, Shalabi, Haneen, Yates, Bonnie, Lichtenstein, Daniel A, Zimmermann, Valérie S, Kondo, Taisuke, Shern, Jack F, Young, Howard A, Taylor, Naomi, Shah, Nirali N, Fry, Terry J

“…Late-onset inflammatory toxicities resembling hemophagocytic lymphohistiocytosis (HLH) or macrophage activation syndrome (MAS) occur after chimeric antigen…”
Get full text

COST action TD1407: network on technology-critical elements (NOTICE)—from environmental processes to human health threats by Cobelo-García, A., Filella, M., Croot, P., Frazzoli, C., Du Laing, G., Ospina-Alvarez, N., Rauch, S., Salaun, P., Schäfer, J., Zimmermann, S.

“…The current socio-economic, environmental and public health challenges that countries are facing clearly need common-defined strategies to inform and support…”
Get full text

Human health risks associated with consumption of fish contaminated with trace elements from intensive mining activities in a peri-urban region by Erasmus, J.H., Zimmermann, S., Smit, N.J., Malherbe, W., Nachev, M., Sures, B., Wepener, V.

“…Worldwide, numerous rural communities and low-income groups depend on fish harvested by subsistence fishers from local rivers and its impoundments as a source…”
Get full text

Electrospray ionization ion mobility spectrometer with new tristate ion gating for improved sensitivity for compounds with lower ion mobility by Thoben, C., Raddatz, C.-R., Lippmann, M., Salehimoghaddam, Z., Zimmermann, S.

“…An electrospray is a dispersed nebula of charged droplets produced under the influence of a strong electric field. The charged droplets subsequently result in…”
Get full text

Size-dependent loss of aboveground animals differentially affects grassland ecosystem coupling and functions by Risch, A. C., Ochoa-Hueso, R., van der Putten, W. H., Bump, J. K., Busse, M. D., Frey, B., Gwiazdowicz, D. J., Page-Dumroese, D. S., Vandegehuchte, M. L., Zimmermann, S., Schütz, M.

“…Increasing evidence suggests that community-level responses to human-induced biodiversity loss start with a decrease of interactions among communities and…”
Get full text

Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis by Matias, Maria I., Yong, Carmen S., Foroushani, Amir, Goldsmith, Chloe, Mongellaz, Cédric, Sezgin, Erdinc, Levental, Kandice R., Talebi, Ali, Perrault, Julie, Rivière, Anais, Dehairs, Jonas, Delos, Océane, Bertand-Michel, Justine, Portais, Jean-Charles, Wong, Madeline, Marie, Julien C., Kelekar, Ameeta, Kinet, Sandrina, Zimmermann, Valérie S., Levental, Ilya, Yvan-Charvet, Laurent, Swinnen, Johannes V., Muljo, Stefan A., Hernandez-Vargas, Hector, Tardito, Saverio, Taylor, Naomi, Dardalhon, Valérie

“…Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show…”
Get full text

Metal accumulation in riverine macroinvertebrates from a platinum mining region by Erasmus, J.H., Malherbe, W., Zimmermann, S., Lorenz, A.W., Nachev, M., Wepener, V., Sures, B., Smit, N.J.

“…[Display omitted] •Quantification of Cr, Ni, Cu, Zn, Cd, Pt, Pb in water, sediment and macroinvertebrates.•Metal contamination increased in water and sediment…”
Get full text

Connections of the Mouse Orbitofrontal Cortex and Regulation of Goal-Directed Action Selection by Brain-Derived Neurotrophic Factor by Zimmermann, Kelsey S, Yamin, John A, Rainnie, Donald G, Ressler, Kerry J, Gourley, Shannon L

“…Abstract Background Distinguishing between actions that are more likely or less likely to be rewarded is a critical aspect of goal-directed decision making…”
Get full text

Improving the performance of cryogenic calorimeters with nonlinear multivariate noise cancellation algorithms by Vetter, K. J., Beretta, M., Capelli, C., Corso, F. Del, Hansen, E. V., Huang, R. G., Kolomensky, Yu. G., Marini, L., Nutini, I., Singh, V., Torres, A., Welliver, B., Zimmermann, S., Zucchelli, S.

“…State-of-the-art physics experiments require high-resolution, low-noise, and low-threshold detectors to achieve competitive scientific results. However,…”
Get full text

Induction and Blockade of Adolescent Cocaine-Induced Habits by DePoy, Lauren M, Zimmermann, Kelsey S, Marvar, Paul J, Gourley, Shannon L

“…Abstract Background Cocaine use during adolescence increases vulnerability to drug dependence and decreases the likelihood that individuals will seek treatment…”
Get full text

Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A by Gonzalez-Menendez, Pedro, Phadke, Ira, Olive, Meagan E., Joly, Axel, Papoin, Julien, Yan, Hongxia, Galtier, Jérémy, Platon, Jessica, Kang, Sun Woo Sophie, McGraw, Kathy L., Daumur, Marie, Pouzolles, Marie, Kondo, Taisuke, Boireau, Stéphanie, Paul, Franciane, Young, David J., Lamure, Sylvain, Mirmira, Raghavendra G., Narla, Anupama, Cartron, Guillaume, Dunbar, Cynthia E., Boyer-Clavel, Myriam, Porat-Shliom, Natalie, Dardalhon, Valérie, Zimmermann, Valérie S., Sitbon, Marc, Dever, Thomas E., Mohandas, Narla, Da Costa, Lydie, Udeshi, Namrata D., Blanc, Lionel, Kinet, Sandrina, Taylor, Naomi

“…•Arginine metabolism regulates erythroid lineage differentiation of human progenitor cells via eIF5A-induced protein synthesis.•RP haploinsufficiency…”
Get full text