Search Results - "Zimmermann, Albert G"

NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways by Allen, Irving C., Moore, Chris B., Schneider, Monika, Lei, Yu, Davis, Beckley K., Scull, Margaret A., Gris, Denis, Roney, Kelly E., Zimmermann, Albert G., Bowzard, John B., Ranjan, Priya, Monroe, Kathryn M., Pickles, Raymond J., Sambhara, Suryaprakash, Ting, Jenny P.Y.

“…The nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate innate immunity. Although the positive regulatory impact of NLRs is…”
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Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling by Duncan, Joseph A, Bergstralh, Daniel T, Wang, Yanhong, Willingham, Stephen B, Ye, Zhengmao, Zimmermann, Albert G, Ting, Jenny Pan-Yun

“…The CATERPILLER (CLR/NLR) gene family encodes a family of putative nucleotide-binding proteins important for host defense. Although nucleotide binding is…”
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NLRX1 is a regulator of mitochondrial antiviral immunity by Lich, John D, Accavitti-Loper, Mary A, Ting, Jenny P-Y, Sun, Lijun, Heise, Mark T, Bergstralh, Daniel T, Lei, Yu, Duncan, Joseph A, Morrison, Thomas E, Ye, Zhengmao, Zimmermann, Albert G, Madden, Victoria J, Moore, Chris B, Chen, Zhijian

“…The RIG-like helicase (RLH) family of intracellular receptors detect viral nucleic acid and signal through the mitochondrial antiviral signalling adaptor MAVS…”
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Plexin-D1 is a novel regulator of germinal centers and humoral immune responses by Holl, Eda K, O'Connor, Brian P, Holl, T Matt, Roney, Kelly E, Zimmermann, Albert G, Jha, Sushmita, Kelsoe, Garnett, Ting, Jenny P-Y

“…Long-lived humoral immune responses depend upon the generation of memory B cells and long-lived plasma cells during the germinal center (GC) reaction. These…”
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The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB by Schneider, Monika, Zimmermann, Albert G, Roberts, Reid A, Zhang, Lu, Swanson, Karen V, Wen, Haitao, Davis, Beckley K, Allen, Irving C, Holl, Eda K, Ye, Zhengmao, Rahman, Adeeb H, Conti, Brian J, Eitas, Timothy K, Koller, Beverly H, Ting, Jenny P-Y

“…Sensors of the NLR family generally activate innate immunity. Ting et al ., however, demonstrate that the little-known NLRC3 negatively regulates Toll-like…”
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Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton by Lake, Jonathan I., Avetisyan, Marina, Zimmermann, Albert G., Heuckeroth, Robert O.

“…Mutations that impair the proliferation of enteric neural crest-derived cells (ENCDC) cause Hirschsprung disease, a potentially lethal birth defect where the…”
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Conventional murine gene targeting by Zimmermann, Albert G, Sun, Yue

“…Murine gene knockout models engineered over the last two decades have continued to demonstrate their potential as invaluable tools in understanding the role of…”
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Characterization of the human inosine-5'-monophosphate dehydrogenase type II gene by Zimmermann, A G, Spychala, J, Mitchell, B S

“…Inosine-5'-monophosphate dehydrogenase (IMPDH) activity and mRNA levels are induced up to 15-fold upon mitogenic or antigenic stimulation of human peripheral…”
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Neural crest requires Impdh 2 for development of the enteric nervous system, great vessels, and craniofacial skeleton by Lake, Jonathan I., Avetisyan, Marina, Zimmermann, Albert G., Heuckeroth, Robert O.

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The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-[kappa]B by Schneider, Monika, Zimmermann, Albert G, Roberts, Reid A, Zhang, Lu, Swanson, Karen V, Wen, Haitao, Davis, Beckley K, Allen, Irving C, Holl, Eda K, Ye, Zhengmao, Rahman, Adeeb H, Conti, Brian J, Eitas, Timothy K, Koller, Beverly H, Ting, Jenny P-y

“…Several members of the NLR family of sensors activate innate immunity. In contrast, we found here that NLRC3 inhibited Toll-like receptor (TLR)-dependent…”
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NLRX1 protein attenuates inflammatory responses to virus infection by interfering with the RIG-I-MAVS signaling pathway and TRAF6 ubiquitin ligase by Allen, Irving C., Moore, Chris B., Schneider, Monika, Lei, Yu, Davis, Beckley K., Scull, Margaret A., Gris, Denis, Roney, Kelly E., Zimmermann, Albert G., Bowzard, John B., Ranjan, Priya, Monroe, Kathryn M., Pickles, Raymond J., Sambhara, Suryaprakash, Ting, Jenny P.Y.

“…The nucleotide-binding domain and leucine-rich repeat containing (NLR) proteins regulate innate immunity. Although the positive regulatory impact of NLRs is…”
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Tissue-specific regulation of the ecto-5'-nucleotidase promoter. Role of the camp response element site in mediating repression by the upstream regulatory region by Spychala, J, Zimmermann, A G, Mitchell, B S

“…We have isolated the 5' region of the ecto-5'-nucleotidase (low K(m) 5'-NT) gene and established that a 969-base pair (bp) fragment confers cell-specific…”
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Tissue-specific Regulation of the Ecto-5′-nucleotidase Promoter by Jozef Spychala, Albert G. Zimmermann, Beverly S. Mitchell

“…We have isolated the 5′ region of the ecto-5′-nucleotidase (low K m 5′-NT) gene and established that a 969-base pair (bp) fragment confers cell-specific…”
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Tissue-specific Regulation of the Ecto-5′-nucleotidase Promoter by Spychala, Jozef, Zimmermann, Albert G., Mitchell, Beverly S.

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Regulation of inosine-5'-monophosphate dehydrogenase type II gene expression in human T cells. Role for a novel 5' palindromic octamer sequence by Zimmermann, A G, Wright, K L, Ting, J P, Mitchell, B S

“…Expression of the gene encoding human inosine- 5'-monophosphate dehydrogenase (IMPDH) type II, an enzyme catalyzing the rate-limiting step in the generation of…”
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Regulation of Inosine-5′-monophosphate Dehydrogenase Type II Gene Expression in Human T Cells by Zimmermann, Albert G., Wright, Kenneth L., Ting, Jenny P.-Y., Mitchell, Beverly S.

“…Expression of the gene encoding human inosine- 5′-monophosphate dehydrogenase (IMPDH) type II, an enzyme catalyzing the rate-limiting step in the generation of…”
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Regulation of Inosine-5′-monophosphate Dehydrogenase Type II Gene Expression in Human T Cells by Albert G. Zimmermann, Kenneth L. Wright, Jenny P.-Y. Ting, Beverly S. Mitchell

“…Expression of the gene encoding human inosine- 5′-monophosphate dehydrogenase (IMPDH) type II, an enzyme catalyzing the rate-limiting step in the generation…”
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Characterization of the Human Inosine-5′-monophosphate Dehydrogenase Type II Gene by Albert G. Zimmermann, Jozef Spychala, Beverly S. Mitchell

“…Inosine-5′-monophosphate dehydrogenase (IMPDH) activity and mRNA levels are induced up to 15-fold upon mitogenic or antigenic stimulation of human peripheral…”
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Prevention of calcium-induced membrane structural alterations in erythrocyte membranes by flunarizine by Thomas, P G, Zimmermann, A G, Verkleij, A J

“…The calcium antagonist flunarizine is shown to be able to prevent particle aggregation, membrane aggregation and blebbing resulting from elevated calcium…”
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Inosine-5'-monophosphate dehydrogenase: regulation of expression and role in cellular proliferation and T lymphocyte activation by Zimmermann, A G, Gu, J J, Laliberté, J, Mitchell, B S

“…Guanine nucleotide synthesis is essential for the maintenance of normal cell growth and function, as well as for cellular transformation and immune responses…”
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