Search Results - "Zimmerman, Sommer S"
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Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators
Published in Journal of medicinal chemistry (27-03-2014)“…NMDA receptors are tetrameric complexes composed of GluN1 and GluN2A–D subunits that mediate a slow Ca2+ -permeable component of excitatory synaptic…”
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Journal Article -
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A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons
Published in ACS chemical neuroscience (21-02-2018)“…N-Methyl-d-aspartate receptors (NMDARs) are ionotropic glutamate receptors that mediate excitatory synaptic transmission and have been implicated in numerous…”
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Journal Article -
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Novel NMDA receptor modulators: an update
Published in Expert opinion on therapeutic patents (01-11-2012)“…The NMDA receptor is a ligand-gated ion channel that plays a critical role in higher level brain processes and has been implicated in a range of neurological…”
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Journal Article -
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Correction to “Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators”
Published in Journal of medicinal chemistry (26-03-2015)Get full text
Journal Article -
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Design, Synthesis, and Biological Evaluation of Subunit-Selective N-Methyl-D-Aspartate Receptor Modulators
Published 01-01-2014“…Chapter 1: N-Methyl-D-aspartate (NMDA) receptors are members of the family of ionotropic glutamate receptors that mediate excitatory neurotransmission. The…”
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Dissertation