Search Results - "Zimmerman, Shawn W"

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    Sperm proteasomes degrade sperm receptor on the egg zona pellucida during mammalian fertilization by Zimmerman, Shawn W, Manandhar, Gaurishankar, Yi, Young-Joo, Gupta, Satish K, Sutovsky, Miriam, Odhiambo, John F, Powell, Michael D, Miller, David J, Sutovsky, Peter

    Published in PloS one (23-02-2011)
    “…Despite decades of research, the mechanism by which the fertilizing spermatozoon penetrates the mammalian vitelline membrane, the zona pellucida (ZP) remains…”
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    Journal Article
  2. 2

    Identification and characterization of RING-finger ubiquitin ligase UBR7 in mammalian spermatozoa by Zimmerman, Shawn W, Yi, Young-Joo, Sutovsky, Miriam, van Leeuwen, Fred W, Conant, Gavin, Sutovsky, Peter

    Published in Cell and tissue research (01-04-2014)
    “…The ubiquitin-proteasome system (UPS) controls intracellular protein turnover in a substrate-specific manner via E3-type ubiquitin ligases. Mammalian…”
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  3. 3

    Interference with the 19S proteasomal regulatory complex subunit PSMD4 on the sperm surface inhibits sperm-zona pellucida penetration during porcine fertilization by Yi, Young-Joo, Manandhar, Gaurishankar, Sutovsky, Miriam, Zimmerman, Shawn W, Jonáková, Věra, van Leeuwen, Fred W, Oko, Richard, Park, Chang-Sik, Sutovsky, Peter

    Published in Cell and tissue research (01-08-2010)
    “…Proteolysis of ubiquitinated sperm and oocyte proteins by the 26S proteasome is necessary for the success of mammalian fertilization, including but not limited…”
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    Journal Article
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