Search Results - "Zimmerman, Anita L."

UV light phototransduction activates transient receptor potential A1 ion channels in human melanocytes by Bellono, Nicholas W., Kammel, Laura G., Zimmerman, Anita L., Oancea, Elena

“…Human skin is constantly exposed to solar ultraviolet radiation (UVR), the most prevalent environmental carcinogen. Humans have the unique ability among…”
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All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: A novel role for photoreceptor retinoids in the response to bright light? by Dean, Dylan M, Nguitragool, Wang, Miri, Andrew, McCabe, Sarah L, Zimmerman, Anita L

“…In retinal rods, light-induced isomerization of 11- cis -retinal to all- trans -retinal within rhodopsin triggers an enzyme cascade that lowers the…”
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The sweet smell of success: Conclusive evidence that cyclic AMP hydrolysis does not trigger fast adaptation in olfactory receptor cells by Zimmerman, Anita L

“…Researchers have assembled an impressive array of negative results that answer a critical question on olfactory transduction. They have ruled out a suspected…”
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Two B or Not Two B? Questioning the Rotational Symmetry of Tetrameric Ion Channels by Zimmerman, Anita L.

“…Members of the voltage-gated family of ion channels generally demonstrate rotational symmetry about their pore regions. Recent evidence suggests that a subset…”
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Characterization of a novel cyclic nucleotide-gated channel from zebrafish brain by Tetreault, Michelle L., Henry, Diane, Horrigan, Diana M., Matthews, Gary, Zimmerman, Anita L.

“…Cyclic nucleotide-gated (CNG) channels have been well characterized in the sensory receptors of vision and olfaction, but their characteristics in other…”
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Capturing ion channel gating: a little salt on the tail does the trick by Zimmerman, Anita L

“…This is a golden age for ion channels. A time when chemistry, molecular biology, and electrophysiology have come together with structural biology to provide…”
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Nanowiring of a redox enzyme by metallized peptides by Yeh, Joanne I., Zimmt, Matthew B., Zimmerman, Anita L.

“…A molecular assembly consisting of a redox enzyme, NADH peroxidase, a metallized double-helical peptide, and a gold nanoparticle immobilized onto a gold wire…”
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All-trans-retinal is a closed-state inhibitor of rod cyclic nucleotide-gated ion channels by McCabe, Sarah L, Pelosi, Diana M, Tetreault, Michelle, Miri, Andrew, Nguitragool, Wang, Kovithvathanaphong, Pranisa, Mahajan, Rahul, Zimmerman, Anita L

“…Rod vision begins when 11-cis-retinal absorbs a photon and isomerizes to all-trans-retinal (ATR) within the photopigment, rhodopsin. Photoactivated rhodopsin…”
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Retinoids restore normal cyclic nucleotide sensitivity of mutant ion channels associated with cone dystrophy by Tetreault, Michelle L, Horrigan, Diana M, Kim, Jennifer A, Zimmerman, Anita L

“…To determine whether inhibition of cyclic nucleotide-gated (CNG) ion channels by retinoids might be useful in treating degenerative retinal diseases in which…”
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Defining the retinoid binding site in the rod cyclic nucleotide-gated channel by Horrigan, Diana M, Tetreault, Michelle L, Tsomaia, Natia, Vasileiou, Chrysoula, Borhan, Babak, Mierke, Dale F, Crouch, Rosalie K, Zimmerman, Anita L

“…Rod vision is initiated when 11-cis-retinal, bound within rhodopsin, absorbs a photon and isomerizes to all-trans-retinal (ATR). This triggers an enzyme…”
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Cyclic nucleotide gated channels by Zimmerman, Anita L

“…Recent studies have revealed that cyclic nucleotide gated channels have a variety of forms and functions. These channels are now thought to be heteromultimers…”
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Cyclic nucleotide-gated ion channels in rod photoreceptors are protected from retinoid inhibition by He, Quanhua, Alexeev, Dmitriy, Estevez, Maureen E, McCabe, Sarah L, Calvert, Peter D, Ong, David E, Cornwall, M Carter, Zimmerman, Anita L, Makino, Clint L

“…In vertebrate rods, photoisomerization of the 11-cis retinal chromophore of rhodopsin to the all-trans conformation initiates a biochemical cascade that closes…”
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Mechanism of inhibition of cyclic nucleotide-gated ion channels by diacylglycerol by Crary, J I, Dean, D M, Nguitragool, W, Kurshan, P T, Zimmerman, A L

“…Cyclic nucleotide-gated (CNG) channels are critical components in the visual and olfactory signal transduction pathways, and they primarily gate in response to…”
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Mutation of a single residue in the S2-S3 loop of CNG channels alters the gating properties and sensitivity to inhibitors by Crary, J I, Dean, D M, Maroof, F, Zimmerman, A L

“…We previously found that native cyclic nucleotide-gated (CNG) cation channels from amphibian rod cells are directly and reversibly inhibited by analogues of…”
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Ultraviolet Light Phototransduction Activates TRPA1 to Mediate Melanin Synthesis in Human Melanocytes by Bellono, Nicholas W., Kammel, Laura G., Zimmerman, Anita L., Oancea, Elena

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Capturing Ion Channel Gating by Zimmerman, Anita L.

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An Additional Retinoid Binding Site in Rhodopsin by Isayama, Tomoki, Okada, Tetsuji, Looney, James D., Crouch, Rosalie K., Zimmerman, Anita L., Makino, Clint L.

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A novel cyclic nucleotide-gated ion channel enriched in synaptic terminals of isotocin neurons in zebrafish brain and pituitary by Khan, S, Perry, C, Tetreault, M.L, Henry, D, Trimmer, J.S, Zimmerman, A.L, Matthews, G

“…Abstract Cyclic nucleotide-gated (CNG) channels are nonselective cation channels opened by binding of intracellular cyclic GMP or cyclic AMP. CNG channels…”
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All-trans-Retinal Shuts Down Rod Cyclic Nucleotidegated Ion Channels: A Novel Role for Photoreceptor Retinoids in the Response to Bright Light? by Dean, Dylan M., Nguitragool, Wang, Miri, Andrew, McCabe, Sarah L., Zimmerman, Anita L.

“…In retinal rods, light-induced isomerization of 11-cis-retinal to all-trans-retinal within rhodopsin triggers an enzyme cascade that lowers the concentration…”
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Protein phosphatases modulate the apparent agonist affinity of the light-regulated ion channel in retinal rods by Gordon, S E, Brautigan, D L, Zimmerman, A L

“…Ion channels directly activated by cGMP mediate the light response in retinal rods. Several components of the enzyme cascade controlling cGMP concentration are…”
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