Search Results - "Zimmer, Jacques"
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Alessandro Moretta and Transporter Associated With Antigen Processing (TAP) Deficiency: On Giant's Shoulders
Published in Frontiers in immunology (15-10-2019)“…The laboratory hosting me for my Ph.D. described in 1994 the first human cases of TAP deficiency in two siblings with recurrent bacterial airway infections and…”
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CD56dimCD16dim Natural Killer (NK) Cells: The Forgotten Population
Published in HemaSphere (01-04-2020)Get full text
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Special Issue "New Developments in Natural Killer Cells for Immunotherapy"
Published in Cells (Basel, Switzerland) (29-05-2023)“…Since their formal discovery in 1975, natural killer (NK) cells have always been proposed in the literature as a potential treatment for cancer and viral…”
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A Hot Topic: Cancer Immunotherapy and Natural Killer Cells
Published in International journal of molecular sciences (12-01-2022)“…Despite significant progress in recent years, the therapeutic approach of the multiple different forms of human cancer often remains a challenge. Besides the…”
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Revisiting the Functional Impact of NK Cells
Published in Trends in immunology (01-06-2018)“…Immune responses are critical for the maintenance of homeostasis but can also upset the equilibrium, depending on the context and magnitude of the response…”
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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia
Published in Proceedings of the National Academy of Sciences - PNAS (22-10-2013)“…Recent studies demonstrated that autophagy is an important regulator of innate immune response. However, the mechanism by which autophagy regulates natural…”
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Editorial: Recent 3D Tumor Models for Testing Immune-Mediated Therapies
Published in Frontiers in immunology (18-11-2021)Get full text
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Airway Natural Killer Cells and Bacteria in Health and Disease
Published in Frontiers in immunology (25-09-2020)“…Natural killer (NK) cells are innate lymphoid cells at the interface between innate and adaptive immunity and mostly studied for their important roles in viral…”
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Revisiting the Role of Neurotrophic Factors in Inflammation
Published in Cells (Basel, Switzerland) (02-04-2020)“…The neurotrophic factors are well known for their implication in the growth and the survival of the central, sensory, enteric and parasympathetic nervous…”
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NK cells in central nervous system disorders
Published in The Journal of immunology (1950) (01-06-2013)“…NK cells are important players in immunity against pathogens and neoplasms. As a component of the innate immune system, they are one of the first effectors on…”
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Two hits are better than one: rational dual strategy efficiently fights neuroblastoma
Published in Signal transduction and targeted therapy (30-04-2024)Get full text
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SARS-CoV-2 transmission risk from asymptomatic carriers: Results from a mass screening programme in Luxembourg
Published in The Lancet regional health. Europe (01-05-2021)“…To accompany the lifting of COVID-19 lockdown measures, Luxembourg implemented a mass screening (MS) programme. The first phase coincided with an early summer…”
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Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
Published in Journal of translational medicine (07-11-2023)“…Abstract Background Combination antiretroviral therapy (cART) has dramatically extended the life expectancy of people living with HIV-1 and improved their…”
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Natural killer cells in atopic and autoimmune diseases of the skin
Published in Journal of allergy and clinical immunology (2010)“…Natural killer (NK) cells are best known for their ability to recognize and kill tumor cells and virally infected cells and for their ability to produce large…”
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The role of haematopoietic growth factors granulocyte colony‐stimulating factor and granulocyte‐macrophage colony‐stimulating factor in the management of drug‐induced agranulocytosis
Published in British journal of haematology (01-07-2010)“…Summary Drug‐induced agranulocytosis (neutrophil count <0·5 × 109/l) is a rare haematological complication with an incidence of no more than 10 cases per…”
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Dietary Modulation Alters Susceptibility to Listeria monocytogenes and Salmonella Typhimurium with or without a Gut Microbiota
Published in mSystems (21-12-2021)“…Food safety has considerably improved worldwide, yet infections with foodborne human enteric pathogens, such as spp. and Salmonella spp., still cause numerous…”
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Unbiased Screening Identifies Functional Differences in NK Cells After Early Life Psychosocial Stress
Published in Frontiers in immunology (30-07-2021)“…Early Life Adversity (ELA) is closely associated with the risk for developing diseases later in life, such as autoimmune diseases, type-2 diabetes and…”
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Imprint of Initial Education and Loss of Ly49C/I in Activated Natural Killer Cells of TAP1-KO and C57BL/6 Wildtype Mice
Published in Frontiers in immunology (14-07-2022)“…Natural killer (NK) cells are important effectors of the innate immune system and participate in the first line of defense against infections and tumors. Prior…”
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Control of NK cell functions by CD4+CD25+ regulatory T cells
Published in Journal of leukocyte biology (01-01-2007)“…Regulatory T cells (Treg) are key players in the maintenance of peripheral tolerance. As a result of suppressive effects on CD4+ and CD8+ effector T cells,…”
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Altered NKG2D function in NK cells induced by chronic exposure to NKG2D ligand–expressing tumor cells
Published in Blood (01-09-2005)“…NKG2D is an activation receptor that allows natural killer (NK) cells to detect diseased host cells. The engagement of NKG2D with corresponding ligand results…”
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