Search Results - "Zillich, Lea"

Methylome-wide change associated with response to electroconvulsive therapy in depressed patients by Sirignano, Lea, Frank, Josef, Kranaster, Laura, Witt, Stephanie H., Streit, Fabian, Zillich, Lea, Sartorius, Alexander, Rietschel, Marcella, Foo, Jerome C.

“…Electroconvulsive therapy (ECT) is a quick-acting and powerful antidepressant treatment considered to be effective in treating severe and…”
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Epigenome-wide association study of alcohol use disorder in five brain regions by Zillich, Lea, Frank, Josef, Streit, Fabian, Friske, Marion M, Foo, Jerome C, Sirignano, Lea, Heilmann-Heimbach, Stefanie, Dukal, Helene, Degenhardt, Franziska, Hoffmann, Per, Hansson, Anita C, Nöthen, Markus M, Rietschel, Marcella, Spanagel, Rainer, Witt, Stephanie H

“…Alcohol use disorder (AUD) is closely linked to the brain regions forming the neurocircuitry of addiction. Postmortem human brain tissue enables the direct…”
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Depression and bipolar disorder subtypes differ in their genetic correlations with biological rhythms by Sirignano, Lea, Streit, Fabian, Frank, Josef, Zillich, Lea, Witt, Stephanie H., Rietschel, Marcella, Foo, Jerome C.

“…Major Depression and Bipolar Disorder Type I (BIP-I) and Type II (BIP-II), are characterized by depressed, manic, and hypomanic episodes in which specific…”
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Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study by Biernacka, Joanna M, Coombes, Brandon J, Batzler, Anthony, Ho, Ada Man-Choi, Geske, Jennifer R, Frank, Josef, Hodgkinson, Colin, Skime, Michelle, Colby, Colin, Zillich, Lea, Pozsonyiova, Sofia, Ho, Ming-Fen, Kiefer, Falk, Rietschel, Marcella, Weinshilboum, Richard, O'Malley, Stephanie S, Mann, Karl, Anton, Ray, Goldman, David, Karpyak, Victor M

“…Naltrexone can aid in reducing alcohol consumption, while acamprosate supports abstinence; however, not all patients with alcohol use disorder (AUD) benefit…”
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Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum by Zillich, Lea, Poisel, Eric, Frank, Josef, Foo, Jerome C., Friske, Marion M., Streit, Fabian, Sirignano, Lea, Heilmann-Heimbach, Stefanie, Heimbach, André, Hoffmann, Per, Degenhardt, Franziska, Hansson, Anita C., Bakalkin, Georgy, Nöthen, Markus M., Rietschel, Marcella, Spanagel, Rainer, Witt, Stephanie H.

“…Alcohol Use Disorder (AUD) is a major contributor to global mortality and morbidity. Postmortem human brain tissue enables the investigation of molecular…”
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Real-time individual benefit from social interactions before and during the lockdown: the crucial role of personality, neurobiology and genes by Monninger, Maximilian, Aggensteiner, Pascal-M., Pollok, Tania M., Reinhard, Iris, Hall, Alisha S. M., Zillich, Lea, Streit, Fabian, Witt, Stephanie-H., Reichert, Markus, Ebner-Priemer, Ulrich, Meyer-Lindenberg, Andreas, Tost, Heike, Brandeis, Daniel, Banaschewski, Tobias, Holz, Nathalie E.

“…Social integration is a major resilience factor for staying healthy. However, the COVID-19-pandemic led to unprecedented restrictions in social life. The…”
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Psychological, endocrine and polygenic predictors of emotional well-being during the COVID-19 pandemic in a longitudinal birth cohort by Nguyen, Thao, Zillich, Lea, Cetin, Metin, Hall, Alisha S M, Foo, Jerome C, Sirignano, Lea, Frank, Josef, Send, Tabea S, Gilles, Maria, Rietschel, Marcella, Deuschle, Michael, Witt, Stephanie H, Streit, Fabian

“…The COVID-19 pandemic severely affected the lives of families and the well-being of both parents and their children. Various factors, including prenatal…”
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DNA methylation in cocaine use disorder-An epigenome-wide approach in the human prefrontal cortex by Poisel, Eric, Zillich, Lea, Streit, Fabian, Frank, Josef, Friske, Marion M, Foo, Jerome C, Mechawar, Naguib, Turecki, Gustavo, Hansson, Anita C, Nöthen, Markus M, Rietschel, Marcella, Spanagel, Rainer, Witt, Stephanie H

“…Cocaine use disorder (CUD) is characterized by a loss of control over cocaine intake and is associated with structural, functional, and molecular alterations…”
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Multi-omics profiling of DNA methylation and gene expression alterations in human cocaine use disorder by Zillich, Eric, Belschner, Hanna, Avetyan, Diana, Andrade-Brito, Diego, Martínez-Magaña, José Jaime, Frank, Josef, Mechawar, Naguib, Turecki, Gustavo, Cabana-Domínguez, Judit, Fernàndez-Castillo, Noèlia, Cormand, Bru, Montalvo-Ortiz, Janitza L., Nöthen, Markus M., Hansson, Anita C., Rietschel, Marcella, Spanagel, Rainer, Witt, Stephanie H., Zillich, Lea

“…Structural and functional changes of the brain are assumed to contribute to excessive cocaine intake, craving, and relapse in cocaine use disorder (CUD)…”
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Neuronal-specific methylome and hydroxymethylome analysis reveal significant loci associated with alcohol use disorder by Andrade-Brito, Diego E, Núñez-Ríos, Diana L, Martínez-Magaña, José Jaime, Nagamatsu, Sheila T, Rompala, Gregory, Zillich, Lea, Witt, Stephanie H, Clark, Shaunna L, Lattig, Maria C, Montalvo-Ortiz, Janitza L

“…Alcohol use disorder (AUD) is a complex condition associated with adverse health consequences that affect millions of individuals worldwide. Epigenetic…”
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Evidence for a shared genetic contribution to loneliness and borderline personality disorder by Schulze, Anna, Streit, Fabian, Zillich, Lea, Awasthi, Swapnil, Hall, Alisha S. M., Jungkunz, Martin, Kleindienst, Nikolaus, Frank, Josef, Schwarze, Cornelia E., Dahmen, Norbert, Schott, Björn H., Nöthen, Markus, Mobascher, Arian, Rujescu, Dan, Lieb, Klaus, Roepke, Stefan, Herpertz, Sabine C., Schmahl, Christian, Bohus, Martin, Ripke, Stephan, Rietschel, Marcella, Lis, Stefanie, Witt, Stephanie

“…Loneliness, influenced by genetic and environmental factors such as childhood maltreatment, is one aspect of interpersonal dysfunction in Borderline…”
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Borderline personality disorder and the big five: molecular genetic analyses indicate shared genetic architecture with neuroticism and openness by Streit, Fabian, Witt, Stephanie H., Awasthi, Swapnil, Foo, Jerome C., Jungkunz, Martin, Frank, Josef, Colodro-Conde, Lucía, Hindley, Guy, Smeland, Olav B., Maslahati, Tolou, Schwarze, Cornelia E., Dahmen, Norbert, Schott, Björn H., Kleindienst, Nikolaus, Hartmann, Annette, Giegling, Ina, Zillich, Lea, Sirignano, Lea, Poisel, Eric, Chen, Chi-Hua, Nöthen, Markus M., Mobascher, Arian, Rujescu, Dan, Lieb, Klaus, Roepke, Stefan, Schmahl, Christian, Bohus, Martin, Ripke, Stephan, Rietschel, Marcella, Andreassen, Ole A.

“…Both environmental (e.g. interpersonal traumatization during childhood and adolescence) and genetic factors may contribute to the development of Borderline…”
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Speech Features as Predictors of Momentary Depression Severity in Patients With Depressive Disorder Undergoing Sleep Deprivation Therapy: Ambulatory Assessment Pilot Study by Wadle, Lisa-Marie, Ebner-Priemer, Ulrich W, Foo, Jerome C, Yamamoto, Yoshiharu, Streit, Fabian, Witt, Stephanie H, Frank, Josef, Zillich, Lea, Limberger, Matthias F, Ablimit, Ayimnisagul, Schultz, Tanja, Gilles, Maria, Rietschel, Marcella, Sirignano, Lea

“…The use of mobile devices to continuously monitor objectively extracted parameters of depressive symptomatology is seen as an important step in the…”
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Association of Locomotor Activity During Sleep Deprivation Treatment With Response by Foo, Jerome Clifford, Sirignano, Lea, Trautmann, Nina, Kim, Jinhyuk, Witt, Stephanie H., Streit, Fabian, Frank, Josef, Zillich, Lea, Meyer-Lindenberg, Andreas, Ebner-Priemer, Ulrich, Schilling, Claudia, Schredl, Michael, Yamamoto, Yoshiharu, Gilles, Maria, Deuschle, Michael, Rietschel, Marcella

“…Disrupted circadian rhythms and sleep patterns are frequently observed features of psychiatric disorders, and especially mood disorders. Sleep deprivation…”
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The interplay of family history of depression and early trauma: associations with lifetime and current depression in the German national cohort (NAKO) by Streit, Fabian, Völker, Maja P, Klinger-König, Johanna, Zillich, Lea, Frank, Josef, Reinhard, Iris, Foo, Jerome C, Witt, Stephanie H, Sirignano, Lea, Becher, Heiko, Obi, Nadia, Riedel, Oliver, Do, Stefanie, Castell, Stefanie, Hassenstein, Max J, Karch, André, Stang, Andreas, Schmidt, Börge, Schikowski, Tamara, Stahl-Pehe, Anna, Brenner, Hermann, Perna, Laura, Greiser, Karin Halina, Kaaks, Rudolf, Michels, Karin B, Franzke, Claus-Werner, Peters, Annette, Fischer, Beate, Konzok, Julian, Mikolajczyk, Rafael, Führer, Amand, Keil, Thomas, Fricke, Julia, Willich, Stefan N, Pischon, Tobias, Völzke, Henry, Meinke-Franze, Claudia, Loeffler, Markus, Wirkner, Kerstin, Berger, Klaus, Grabe, Hans J, Rietschel, Marcella

“…Family history of depression and childhood maltreatment are established risk factors for depression. However, how these factors are interrelated and jointly…”
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TU57. DISENTANGLING GENETIC ARCHITECTURE OF BIPOLAR AND ALCOHOL USE DISORDERS by Foo, Jerome, Zillich, Lea, Streit, Fabian

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W53. LIFETIME AND CURRENT DEPRESSION IN THE GERMAN NATIONAL COHORT (NAKO) by Streit, Fabian, Zillich, Lea, Rietschel, Marcella, Berger, Klaus

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Neuronal-Specific Methylome and Hydroxymethylome Analysis Reveal Replicated and Novel Loci Associated With Alcohol Use Disorder by Andrade-Brito, Diego, Nunez-Rios, Diana, Martinez-Magaña, Jaime, Rompala, Gregory, Zillich, Lea, Witt, Stephanie, Clark, Shaunna, Montalvo-Ortiz, Janitza

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Cell Type-Specific Multi-Omics Analysis of Cocaine Use Disorder in the Human Caudate Nucleus Suggests Phosphodiesterases as a Pharmacological Target by Zillich, Lea, Artioli, Annasara, Phorala, Veronika, Zillich, Eric, Jabali, Ammar, Spanagel, Rainer, Rietschel, Marcella, Walss-Bass, Consuelo, Bernardi, Rick, Koch, Philipp, Witt, Stephanie

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Investigating the Molecular Mechanisms of Alcohol Use Disorder in Postmortem Human Brain Tissue by Zillich, Lea, Poisel, Eric, Frank, Josef, Foo, Jerome C., Streit, Fabian, Hansson, Anita C., Nöthen, Markus M., Rietschel, Marcella, Moser, Dirk, Spanagel, Rainer, Witt, Stephanie H.

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