Complications following acute ischemic stroke

Complications following acute ischemic stroke

The objective of this study was to assess typical early-onset complications following ischemic stroke in a large, hospital-based cohort to provide clinical data for future randomized trials and quality standards in clinical routine. 3,866 patients with acute ischemic stroke were prospectively docume...

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Bibliographic Details
Published in:European neurology Vol. 48; no. 3; p. 133
Main Authors: Weimar, Christian, Roth, Michael P, Zillessen, Gesine, Glahn, Jörg, Wimmer, Martin L J, Busse, Otto, Haberl, Roman L, Diener, Hans-Christoph
Format: Journal Article
Language:English
Published: Switzerland 01-01-2002
Subjects:
Aged
Arteriosclerosis - physiopathology
Brain Ischemia - complications
Brain Ischemia - physiopathology
Brain Stem Infarctions - physiopathology
Cerebral Hemorrhage - etiology
Female
Fever - etiology
Humans
Hypertension - etiology
Intracranial Hypertension - etiology
Male
Pneumonia - etiology
Randomized Controlled Trials as Topic
Recurrence
Risk Factors
Stroke - complications
Stroke - physiopathology
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Summary:The objective of this study was to assess typical early-onset complications following ischemic stroke in a large, hospital-based cohort to provide clinical data for future randomized trials and quality standards in clinical routine. 3,866 patients with acute ischemic stroke were prospectively documented in 14 Neurology Departments with an acute stroke unit. Within the first week after admission, increased intracranial pressure (7.6%) and recurrent cerebral ischemia (5.1%) were the most frequent neurological complications. Fever >38 degrees C (13.2%), severe arterial hypertension (7.5%) and pneumonia (7.4%) were the most frequent medical complications. Multivariate regression analysis yielded brain stem infarction and large-artery atherosclerosis as independent predictors for early recurrent ischemic stroke. This study provides representative data on onset and severity of early neurological and medical complications as well as possible predictors for early recurrent cerebral ischemia following acute ischemic stroke.
ISSN:0014-3022
DOI:10.1159/000065512