Search Results - "Zile, Maija H."

Function of vitamin A in vertebrate embryonic development by Zile, M H

“…Advances in molecular biology and retinoic acid receptor research have significantly contributed to the understanding of the role of vitamin A during…”
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Retinoids control anterior and dorsal properties in the developing forebrain by Halilagic, Aida, Ribes, Vanessa, Ghyselinck, Norbert B., Zile, Maija H., Dollé, Pascal, Studer, Michèle

“…We have previously shown that retinoic acid (RA) synthesized by the retinaldehyde dehydrogenase 2 (RALDH2) is required in forebrain development. Deficiency in…”
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Vitamin A-not for your eyes only: requirement for heart formation begins early in embryogenesis by Zile, Maija H

“…Vitamin A insufficiency has profound adverse effects on embryonic development. Major advances in understanding the role of vitamin A in vertebrate heart…”
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Distinct roles for hindbrain and paraxial mesoderm in the induction and patterning of the inner ear revealed by a study of vitamin-A-deficient quail by Kil, Sung-Hee, Streit, Andrea, Brown, Stephen T., Agrawal, Nidhi, Collazo, Andres, Zile, Maija H., Groves, Andrew K.

“…The hindbrain and cranial paraxial mesoderm have been implicated in the induction and patterning of the inner ear, but the precise role of the two tissues in…”
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A novel role for retinoids in patterning the avian forebrain during presomite stages by Halilagic, Aida, Zile, Maija H, Studer, Michèle

“…Retinoids, and in particular retinoic acid (RA), are known to induce posterior fates in neural tissue. However, alterations in retinoid signalling dramatically…”
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Retinoic acid is a negative physiological regulator of N-cadherin during early avian heart morphogenesis by Romeih, Mahmoud, Cakstina, Inese, Zile, Maija H

“…The vitamin A-deficient (VAD) early avian embryo has a grossly abnormal cardiovascular system that is rescued by treating the embryo with the vitamin A-active…”
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Transforming growth factor β2 is negatively regulated by endogenous retinoic acid during early heart morphogenesis by Ghatpande, Satish K, Zhou, Hui-Ren, Cakstina, Inese, Carlson, Christopher, Rondini, Elizabeth A, Romeih, Mahmoud, Zile, Maija H

“…Vitamin A-deficient (VAD) quail embryos lack the vitamin A-active form, retinoic acid (RA) and are characterized by a phenotype that includes a grossly…”
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Retinoic Acid Is a Potent Regulator of Growth Plate Chondrogenesis by De Luca, Francesco, Uyeda, Jennifer A, Mericq, Veronica, Mancilla, Edna E, Yanovski, Jack A, Barnes, Kevin M, Zile, Maija H, Baron, Jeffrey

“…Vitamin A deficiency and excess both cause abnormalities in mammalian longitudinal bone growth. Because all-trans retinoic acid (RA) is synthesized from…”
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Retinoid Signaling Is Required to Complete the Vertebrate Cardiac Left/Right Asymmetry Pathway by Zile, Maija H, Kostetskii, Igor, Yuan, Saying, Kostetskaia, Ekaterina, St. Amand, Tara R, Chen, YiPing, Jiang, Weihong

“…Vitamin A-deficient (VAD) quail embryos have severe abnormalities, including a high incidence of reversed cardiac situs. Using this model we examined in vivo…”
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The expression of Stra6 and Rdh10 in the avian embryo and their contribution to the generation of retinoid signatures by Reijntjes, Susan, Zile, Maija H, Maden, Malcolm

“…Two new components of the retinoic acid (RA) synthetic pathway, the cell surface receptor for retinol, Stra6, and the enzyme converting retinol into retinal,…”
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Primary culture of avian embryonic heart forming region cells to study the regulation of vertebrate early heart morphogenesis by vitamin A by Cakstina, Inese, Riekstina, Una, Boroduskis, Martins, Nakurte, Ilva, Ancans, Janis, Zile, Maija H, Muiznieks, Indrikis

“…Important knowledge about the role of vitamin A in vertebrate heart development has been obtained using the vitamin A-deficient avian in ovo model which…”
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Vitamin a requirement for early cardiovascular morphogenesis specification in the vertebrate embryo: insights from the avian embryo by Zile, Maija H

“…Vitamin A is required throughout the life cycle, including crucial stages of embryonic and fetal development. With the identification of retinoic acid-specific…”
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Retinoid signalling is required for information transfer from mesoderm to neuroectoderm during gastrulation by Lloret-Vilaspasa, Ferran, Jansen, Hans J, de Roos, Koen, Chandraratna, Rosh A S, Zile, Maija H, Stern, Claudio D, Durston, Antony J

“…The hindbrain region of the vertebrate central nervous system (CNS) presents a complex regionalisation. It consists of 7-8 distinct morphological segments…”
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Retinoid signaling regulates primitive (yolk sac) hematopoiesis by Ghatpande, Satish, Ghatpande, Ashwini, Sher, Justin, Zile, Maija H., Evans, Todd

“…It is known from nutritional studies that vitamin A is an important factor for normal hematopoiesis, though it has been difficult to define its precise role…”
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A ryanodine receptor-dependent Cai2+ asymmetry at Hensen's node mediates avian lateral identity by Garic-Stankovic, Ana, Hernandez, Marcos, Flentke, George R., Zile, Maija H., Smith, Susan M.

“…In mouse, the establishment of left-right (LR) asymmetry requires intracellular calcium (Ca i 2+ ) enrichment on the left of the node. The use of Ca i 2+…”
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Retinoid receptors and vitamin A deficiency: differential patterns of transcription during early avian development and the rapid induction of RARs by retinoic acid by Cui, Jian, Michaille, Jean-Jacques, Jiang, Weihong, Zile, Maija H

“…The functional links of specific retinoid receptors to early developmental events in the avian embryo are not known. Before such studies are undertaken,…”
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Induction of Normal Cardiovascular Development in the Vitamin A-Deprived Quail Embryo by Natural Retinoids by Dersch, Helen, Zile, Maija H.

“…The biological activity of various natural retinoids and the time "window" when vitamin A activity is required for normal cardiovascular development were…”
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Vitamin A and embryonic development: an overview by Zile, M H

“…Vitamin A is an essential micronutrient throughout the life cycle. Its active form, retinoic acid via retinoid receptors, is involved in signal transduction…”
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Critical role for retinol in the generation/differentiation of angioblasts required for embryonic blood vessel formation by LaRue, Amanda C., Argraves, W. Scott, Zile, Maija H., Drake, Christopher J.

“…Numerous studies demonstrate that vitamin A (retinol) deficiency causes abnormal cardiovascular morphogenesis. We evaluated the impact of retinol deficiency on…”
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Chick CFC Controls Lefty1 Expression in the Embryonic Midline and Nodal Expression in the Lateral Plate by Schlange, Thomas, Schnipkoweit, Ingo, Andrée, Birgit, Ebert, Andreas, Zile, Maija H., Arnold, Hans-Henning, Brand, Thomas

“…Members of the EGF-CFC family of proteins have recently been implicated as essential cofactors for Nodal signaling. Here we report the isolation of chick CFC…”
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