Search Results - "Zijlmans, Henry J. M. A. A."

PD-L1 and PD-L2 Expression in Cervical Cancer: Regulation and Biomarker Potential by Rotman, Jossie, den Otter, Leontine A S, Bleeker, Maaike C G, Samuels, Sanne S, Heeren, A Marijne, Roemer, Margaretha G M, Kenter, Gemma G, Zijlmans, Henry J M A A, van Trommel, Nienke E, de Gruijl, Tanja D, Jordanova, Ekaterina S

“…PD-1/PD-L1 immune checkpoint inhibitors show potential for cervical cancer treatment. However, low response rates suggest that patient selection based on PD-L1…”
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HPV16 E7 DNA tattooing: safety, immunogenicity, and clinical response in patients with HPV-positive vulvar intraepithelial neoplasia by Samuels, Sanne, Marijne Heeren, A., Zijlmans, Henry J. M. A. A., Welters, Marij J. P., van den Berg, Joost H., Philips, Daisy, Kvistborg, Pia, Ehsan, Ilina, Scholl, Suzy M. E., Nuijen, Bastiaan, Schumacher, Ton N. M., van Beurden, Marc, Jordanova, Ekaterina S., Haanen, John B. A. G., van der Burg, Sjoerd H., Kenter, Gemma G.

“…Background Usual type vulvar intraepithelial neoplasia (uVIN) is caused by HPV, predominantly type 16. Several forms of HPV immunotherapy have been studied,…”
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Immune landscape in vulvar cancer-draining lymph nodes indicates distinct immune escape mechanisms in support of metastatic spread and growth by Heeren, Anne Marijne, Rotman, Jossie, Samuels, Sanne, Zijlmans, Henry J M A A, Fons, Guus, van de Vijver, Koen K, Bleeker, Maaike C G, Kenter, Gemma G, Jordanova, Ekaterina J, de Gruijl, Tanja D

“…BackgroundTherapeutic immune intervention is highly dependent on the T-cell priming and boosting capacity of tumor-draining lymph nodes (TDLN). In vulvar…”
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Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8 + T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma by Rotman, Jossie, Heeren, A Marijne, Gassama, Awa A, Lougheed, Sinead M, Pocorni, Noëlle, Stam, Anita G M, Bleeker, Maaike C G, Zijlmans, Henry J M A A, Mom, Constantijne H, Kenter, Gemma G, Jordanova, Ekaterina S, de Gruijl, Tanja D

“…Adenocarcinoma of the uterine cervix is the second most common type of cervical cancer after squamous cell carcinoma (SCC). Although both subtypes are treated…”
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Fluorochrome-labeled Tyramides: Use in Immunocytochemistry and Fluorescence In Situ Hybridization by van Gijlswijk, Rob P. M, Zijlmans, Henry J. M. A. A, Wiegant, Joop, Bobrow, Mark N, Erickson, Thomas J, Adler, Karl E, Tanke, Hans J, Raap, Anton K

“…The peroxidase-mediated deposition of hapten- and fluorochrome-labeled tyramides has recently been shown to increase the sensitivity of immunofluoresence and…”
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Role of tumor‐derived proinflammatory cytokines GM‐CSF, TNF‐α, and IL‐12 in the migration and differentiation of antigen‐presenting cells in cervical carcinoma by Zijlmans, Henry J.M.A.A., Fleuren, Gert Jan, Baelde, Hans J., Eilers, Paul H.C., Kenter, Gemma G., Gorter, Arko

“…BACKGROUND. Proinflammatory cytokines are important in modifying the activity, differentiation, and migration of antigen‐presenting cells and may influence the…”
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EMMPRIN‐induced MMP‐2 activation cascade in human cervical squamous cell carcinoma by Sier, Cornelis F.M., Zuidwijk, Kim, Zijlmans, Henry J.M.A.A., Hanemaaijer, Roeland, Mulder‐Stapel, Adri A., Prins, Frans A., Dreef, Enno J., Kenter, Gemma G., Fleuren, Gert Jan, Gorter, Arko

“…Tumor progression and recurrence of cervical cancer is associated with upregulation of matrix metalloproteinase 2 (MMP‐2). We evaluated the location, origin…”
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Endothelium specific matrilysin (MMP-7) expression in human cancers by Sier, Cornelis F.M., Hawinkels, Lukas J.A.C., Zijlmans, Henry J.M.A.A., Zuidwijk, Kim, de Jonge-Muller, Eveline S.M., Ferreira, Valérie, Hanemaaijer, Roeland, Mulder-Stapel, Adri A., Kenter, Gemma G., Verspaget, Hein W., Gorter, Arko

“…Over-expression of matrilysin (MMP-7) is predominantly associated with epithelial (pre)malignant cells. In the present study MMP-7 expression is also found in…”
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Reconstruction of the Meatus Urethrae After Oncologic Vulvectomy: Outcome of 42 Vaginal Flap Advancements in 41 Women by Lange, Maurits, Hage, J. Joris, Hartveld, Loes, Zijlmans, Henry J.M.A.A., van Beurden, Marc

“…Resection of the distal part of the urethra is performed in 15% to 55% of women with vulvar cancer to achieve radicality of vulvectomy. Urinary reconstruction…”
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Surgical navigation for targeted retroperitoneal lymph-node removal: a randomised, controlled, phase 3 trial by Groen, Harald C., Wit, Esther M.K., Heerink, Wouter J., Kuhlmann, Koert F.D., Nijkamp, Jasper A., van Veen, Ruben, Schoots, Ivo G., Balduzzi, Sara, Zijlmans, Henry J.M.A.A., van Leeuwen, Pim J., van der Poel, Henk G., Ruers, Theo J.M.

“…Metastatic retroperitoneal lymph node dissection (LND) for nodal recurrence is applied for a variety of cancers, such as urological, gynaecological and rectal…”
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HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN): a phase I/II clinical trial by Bakker, Noor Alida Maria, Rotman, Jossie, van Beurden, Marc, Zijlmans, Henry J MAA, van Ruiten, Maartje, Samuels, Sanne, Nuijen, Bastiaan, Beijnen, Jos, De Visser, Karin, Haanen, John, Schumacher, Ton, de Gruijl, Tanja D, Jordanova, Ekaterina S, Kenter, Gemma G, van den Berg, Joost H, van Trommel, Nienke E

“…BackgroundUsual vulvar intraepithelial neoplasia (uVIN) is a premalignancy caused by persistent infection with high-risk types of human papillomavirus (HPV),…”
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Role of tumor-derived proinflammatory cytokines GM-CSF, TNF- alpha , and IL-12 in the migration and differentiation of antigen-presenting cells in cervical carcinoma by Zijlmans, Henry J M A A, Fleuren, Gert Jan, Baelde, Hans J, Eilers, Paul H C, Kenter, Gemma G, Gorter, Arko

“…BACKGROUND. Proinflammatory cytokines are important in modifying the activity, differentiation, and migration of antigen-presenting cells and may influence the…”
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