Search Results - "Zijenah, Lynn S"
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Effect on mortality of point-of-care, urine-based lipoarabinomannan testing to guide tuberculosis treatment initiation in HIV-positive hospital inpatients: a pragmatic, parallel-group, multicountry, open-label, randomised controlled trial
Published in The Lancet (British edition) (19-03-2016)“…Summary Background HIV-associated tuberculosis is difficult to diagnose and results in high mortality. Frequent extra-pulmonary presentation, inability to…”
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Effect of new tuberculosis diagnostic technologies on community-based intensified case finding: a multicentre randomised controlled trial
Published in The Lancet infectious diseases (01-04-2017)“…Summary Background Inadequate case detection results in high levels of undiagnosed tuberculosis in sub-Saharan Africa. Data for the effect of new diagnostic…”
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Mother-to-child transmission of HIV-1 and infant mortality in the first six months of life, in the era of Option B Plus combination antiretroviral therapy
Published in International journal of infectious diseases (01-08-2021)“…•Mother-to-child transmission of HIV occurs intrauterine, intrapartum, and postpartum.•Intrauterine is the major route of mother-to-child transmission of…”
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CYP3A5 GENETIC POLYMORPHISMS IN DIFFERENT ETHNIC POPULATIONS
Published in Drug metabolism and disposition (01-07-2005)“…Cyp3A5 activity varies within any given ethnic population, suggesting that genetic variation within the Cyp3A5 gene may be the most important contributor to…”
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Effects of a Single Large Dose of Vitamin A, Given during the Postpartum Period to HIV-Positive Women and Their Infants, on Child HIV Infection, HIV-Free Survival, and Mortality
Published in The Journal of infectious diseases (15-03-2006)“…BackgroundLow maternal serum retinol level is a risk factor for mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV). Multiple-large-dose…”
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Surveillance of transmitted antiretroviral drug resistance among HIV-1 infected women attending antenatal clinics in Chitungwiza, Zimbabwe
Published in PloS one (16-06-2011)“…The rapid scale-up of highly active antiretroviral therapy (HAART) and use of single dose Nevirapine (SD NVP) for prevention of mother-to-child transmission…”
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Naturally-occurring genetic variants in human DC-SIGN increase HIV-1 capture, cell-transfer and risk of mother-to-child transmission
Published in PloS one (10-07-2012)“…Mother-to-child transmission (MTCT) is the main cause of HIV-1 infection in children worldwide. Dendritic cell-specific ICAM-3 grabbing-nonintegrin (DC-SIGN,…”
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Genetic Variants in Nonclassical Major Histocompatibility Complex Class I Human Leukocyte Antigen (HLA)–E and HLA-G Molecules Are Associated with Susceptibility to Heterosexual Acquisition of HIV-1
Published in The Journal of infectious diseases (15-01-2006)“…Human leukocyte antigen (HLA)–E and HLA-G molecules act as powerful modulators of the innate immune response. The present study shows that the HLA-EG genetic…”
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Genetic Analyses of HIV-1 env Sequences Demonstrate Limited Compartmentalization in Breast Milk and Suggest Viral Replication within the Breast That Increases with Mastitis
Published in Journal of Virology (01-10-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High Frequency of Syncytium-Inducing and CXCR4-Tropic Viruses among Human Immunodeficiency Virus Type 1 Subtype C-Infected Patients Receiving Antiretroviral Treatment
Published in Journal of Virology (01-07-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Functional genetic variants in DC-SIGNR are associated with mother-to-child transmission of HIV-1
Published in PloS one (07-10-2009)“…Mother-to-child transmission (MTCT) is the main cause of HIV-1 infection in children worldwide. Given that the C-type lectin receptor, dendritic cell-specific…”
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Laboratory Indicators of Mastitis Are Not Associated with Elevated HIV-1 DNA Loads or Predictive of HIV-1 RNA Loads in Breast Milk
Published in The Journal of infectious diseases (15-08-2007)“…Background. Mother-to-child transmission (MTCT) of HIV-1 has been associated with symptomatic and asymptomatic mastitis and with the quantity of HIV-1 RNA and…”
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Affordable flow cytometry for enumeration of absolute CD4+ T-lymphocytes to identify subtype C HIV-1 infected adults requiring antiretroviral therapy (ART) and monitoring response to ART in a resource-limited setting
Published in Journal of translational medicine (14-08-2006)“…The World Health Organization (WHO)'s "3 x 5 program" has spurred efforts to place 3 million people on combination antiretroviral therapy (ART) for treatment…”
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HIV-1 subtype C reverse transcriptase and protease genotypes in Zimbabwean patients failing antiretroviral therapy
Published in AIDS research and human retroviruses (10-12-2002)“…HIV-1 drug resistance mutations have been identified and characterized mostly in subtype B HIV-1 infection. The extent to which antiretroviral drugs select for…”
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T lymphocytes among HIV-infected and -uninfected infants: CD4/CD8 ratio as a potential tool in diagnosis of infection in infants under the age of 2 years
Published in Journal of translational medicine (01-02-2005)“…BACKGROUND: Serologic tests for HIV infection in infants less than 18 months do not differentiate exposure and infection since maternally acquired IgG…”
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Mycobacterium tuberculosis/HIV-1 Coinfection and Disease: Role of Human Leukocyte Antigen Variation
Published in The Journal of infectious diseases (15-03-2004)“…Genetic variation influences immune responses and may contribute to differential development of tuberculosis (TB), particularly in immunosuppressed…”
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Effect of postpartum maternal or neonatal vitamin A supplementation on infant mortality among infants born to HIV-negative mothers in Zimbabwe
Published in The American journal of clinical nutrition (01-02-2005)“…Background: Young infants are at risk of vitamin A deficiency. Supplementation of breastfeeding mothers improves the vitamin A status of their infants, but…”
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CD4 T cell measurements in the management of antiretroviral therapy—A review with an emphasis on pediatric HIV‐infected patients
Published in Cytometry. Part B, Clinical cytometry (2008)“…The measurement of both the percentage (in pediatric patients aged less than 5 or 6 years) and the absolute number of circulating CD4+ T cells remains the…”
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Cytomegalovirus and Epstein-Barr virus in breast milk are associated with HIV-1 shedding but not with mastitis
Published in AIDS (London) (31-07-2008)“…Breast milk HIV-1 load is associated with clinical and subclinical mastitis, and both milk viral load and mastitis are associated with increased…”
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HIV incidence among post-partum women in Zimbabwe : risk factors and the effect of vitamin A supplementation
Published in AIDS (London) (26-06-2006)“…To test whether post-partum vitamin A supplementation can reduce incident HIV among post-partum women and identify risk factors for HIV incidence. Randomized,…”
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