Search Results - "Ziglioli, Nicoletta"
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Computational reactive–diffusive modeling for stratification and prognosis determination of patients with breast cancer receiving Olaparib
Published in Scientific reports (24-07-2023)“…Mathematical models based on partial differential equations (PDEs) can be exploited to handle clinical data with space/time dimensions, e.g. tumor growth…”
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Clinical, Radiometabolic and Immunologic Effects of Olaparib in Locally Advanced Triple Negative Breast Cancer: The OLTRE Window of Opportunity Trial
Published in Frontiers in oncology (28-06-2021)“…Olaparib is effective in metastatic triple negative breast cancer (TNBC) carrying germline mutations in DNA damage repair (DDR) genes (g -mut). The OLTRE…”
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Tumor Type Agnostic Therapy Carrying BRAF Mutation: Case Reports and Review of Literature
Published in Pharmaceuticals (Basel, Switzerland) (16-02-2021)“…Precision medicine is based on molecular and genotypic patient characterization to define specific target treatment. BRAF mutation is an oncogenic driver, and…”
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Assessing the long-term prognostic ability of the 70 gene expression signature MammaPrint in an Italian single-center prospective cohort study of early-stage intermediate-risk breast cancer patients
Published in Heliyon (15-11-2024)“…The aim of this study was to assess the prognostic performance of the 70-gene signature, MammaPrint, in an Italian single-center prospective cohort of…”
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Addendum: Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study
Published in Oncotarget (06-12-2022)Get full text
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Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study
Published in Oncotarget (09-06-2020)“…INTRODUCTIONReliable biomarkers of response to mTOR inhibition are yet to be identified. As mTOR is heavily implicated in cell-metabolism, we investigated the…”
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Early Changes of the Standardized Uptake Values (SUV max ) Predict the Efficacy of Everolimus-Exemestane in Patients with Hormone Receptor-Positive Metastatic Breast Cancer
Published in Cancers (10-11-2020)“…The mTORC1 inhibitor everolimus has been approved in combination with the aromatase inhibitor exemestane for the treatment of hormone receptor-positive (HR+)…”
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Tumor Type Agnostic Therapy Carrying BRAF Mutation: Case Reports and Review of Literature
Published in Pharmaceuticals (Basel, Switzerland) (16-02-2021)“…BACKGROUNDPrecision medicine is based on molecular and genotypic patient characterization to define specific target treatment. BRAF mutation is an oncogenic…”
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