Search Results - "ZiglerJr, J Samuel"
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A Novel Method of Mouse RPE Explant Culture and Effective Introduction of Transgenes Using Adenoviral Transduction for In Vitro Studies in AMD
Published in International journal of molecular sciences (05-11-2021)“…Degeneration of retinal pigment epithelium (RPE) is one of the most critical phenotypic changes of age-related macular degeneration (AMD), the leading cause of…”
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Mitophagy in Astrocytes Is Required for the Health of Optic Nerve
Published in Cells (Basel, Switzerland) (01-10-2023)“…Mitochondrial dysfunction in astrocytes has been implicated in the development of various neurological disorders. Mitophagy, mitochondrial autophagy, is…”
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Microglia-Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model
Published in Cells (Basel, Switzerland) (01-11-2022)“…In dry age-related macular degeneration (AMD), inflammation plays a key role in disease pathogenesis. Innate immune cells such as microglia and neutrophils…”
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Gene duplication and separation of functions in [alpha]B-crystallin from zebrafish (Danio rerio)
Published in The FEBS journal (01-02-2006)“…We previously reported that zebrafish alpha B-crystallin is not constitutively expressed in nervous or muscular tissue and has reduced chaperone-like activity…”
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