Search Results - "Zigangirova, Nailya A."

Fluorothiazinon, a small-molecular inhibitor of T3SS, suppresses salmonella oral infection in mice by Zigangirova, Nailya A., Nesterenko, Ludmila N., Sheremet, Anna B., Soloveva, Anna V., Luyksaar, Sergey I., Zayakin, Egor S., Balunets, Denis V., Gintsburg, Alexandr L.

“…Therapeutic strategies that target bacterial virulence have received considerable attention. The type III secretion system (T3SS) is important for bacterial…”
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Naphthyl-Substituted Indole and Pyrrole Carboxylic Acids as Effective Antibiotic Potentiators—Inhibitors of Bacterial Cystathionine γ-Lyase by Kuzovlev, Andrey S, Zybalov, Mikhail D, Golovin, Andrey V, Gureev, Maxim A, Kasatkina, Mariia A, Biryukov, Mikhail V, Belik, Albina R, Silonov, Sergey A, Yunin, Maxim A, Zigangirova, Nailya A, Reshetnikov, Vasiliy V, Isakova, Yulia E, Porozov, Yuri B, Ivanov, Roman A

“…Over the past decades, the problem of bacterial resistance to most antibiotics has become a serious threat to patients’ survival. Nevertheless, antibiotics of…”
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Preventative treatment with Fluorothiazinon suppressed Acinetobacter baumannii-associated septicemia in mice by Bondareva, Nataliya E., Soloveva, Anna V., Sheremet, Anna B., Koroleva, Ekaterina A., Kapotina, Lidiya N., Morgunova, Elena Y., Luyksaar, Sergei I., Zayakin, Egor S., Zigangirova, Nailya A.

“…The high prevalence of multidrug-resistant Acinetobacter baumannii has emerged as a serious problem in the treatment of nosocomial infections in the past three…”
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Antiviral Activity of N1,N3-Disubstituted Uracil Derivatives against SARS-CoV-2 Variants of Concern by Siniavin, Andrei E., Novikov, Mikhail S., Gushchin, Vladimir A., Terechov, Alexander A., Ivanov, Igor A., Paramonova, Maria P., Gureeva, Elena S., Russu, Leonid I., Kuznetsova, Nadezhda A., Shidlovskaya, Elena V., Luyksaar, Sergei I., Vasina, Daria V., Zolotov, Sergei A., Zigangirova, Nailya A., Logunov, Denis Y., Gintsburg, Alexander L.

“…Despite the widespread use of the COVID-19 vaccines, the search for effective antiviral drugs for the treatment of patients infected with SARS-CoV-2 is still…”
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Synthesis and Antiviral Activity of Novel β-D-N4-Hydroxycytidine Ester Prodrugs as Potential Compounds for the Treatment of SARS-CoV-2 and Other Human Coronaviruses by Darnotuk, Elizaveta S, Siniavin, Andrei E, Shastina, Natal'ya S, Luyksaar, Sergey I, Inshakova, Anna M, Bondareva, Natalia E, Zolotov, Sergey A, Lubenec, Nadezhda L, Sheremet, Anna B, Logunov, Denis Y, Zigangirova, Nailya A, Gushchin, Vladimir A, Gintsburg, Alexander L

“…The spread of COVID-19 infection continues due to the emergence of multiple transmissible and immune-evasive variants of the SARS-CoV-2 virus. Although various…”
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A small-molecule compound belonging to a class of 2,4-disubstituted 1,3,4-thiadiazine-5-ones suppresses Salmonella infection in vivo by Nesterenko, Ludmila N, Zigangirova, Nailya A, Zayakin, Egor S, Luyksaar, Sergey I, Kobets, Natalie V, Balunets, Denis V, Shabalina, Ludmila A, Bolshakova, Tatiana N, Dobrynina, Olga Y, Gintsburg, Alexander L

“…Therapeutic strategies that target bacterial virulence have received considerable attention. The type III secretion system (T3SS) is important for bacterial…”
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A New "Non-Traditional" Antibacterial Drug Fluorothiazinone-Clinical Research in Patients with Complicated Urinary Tract Infections by Zigangirova, Nailya A, Lubenec, Nadezda L, Beloborodov, Vladimir B, Sheremet, Anna B, Nelyubina, Stanislava A, Bondareva, Nataliia E, Zakharov, Konstantin A, Luyksaar, Sergey I, Zolotov, Sergey A, Levchenko, Evgenia U, Luyksaar, Svetlana V, Koroleva, Ekaterina A, Fedina, Elena D, Simakova, Yana V, Pushkar, Dmitry Yu, Gintzburg, Alexander L

“…In order to combat resistance, it is necessary to develop antimicrobial agents that act differently from conventional antibiotics. Fluorothiazinone, 300 mg…”
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Pharmacokinetics, quorum-sensing signal molecules and tryptophan-related metabolomics of the novel anti-virulence drug Fluorothiazinon in a Pseudomonas aeruginosa-induced pneumonia murine model by Savitskii, Mark V., Moskaleva, Natalia E., Brito, Alex, Zigangirova, Nailya A., Soloveva, Anna V., Sheremet, Anna B., Bondareva, Natalia E., Lubenec, Nadezhda L., Kuznetsov, Roman M., Samoylov, Viktor M., Tagliaro, Franco, Appolonova, Svetlana A.

“…Pseudomonas aeruginosa (PA) infection is commonly associated with hospital-acquired infections in patients with immune deficiency and/or severe lung diseases…”
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Pharmacokinetics, tissue distribution, bioavailability and excretion of the anti-virulence drug Fluorothiazinon in rats and rabbits by Savitskii, Mark V., Moskaleva, Natalia E., Brito, Alex, Markin, Pavel A., Zigangirova, Nailya A., Soloveva, Anna V., Sheremet, Anna B., Bondareva, Natalia E., Lubenec, Nadezhda L., Tagliaro, Franco, Tarasov, Vadim V., Tatzhikova, Kristina A., Appolonova, Svetlana A.

“…Growing antimicrobial resistance has accelerated the development of anti-virulence drugs to suppress bacterial toxicity without affecting cell viability…”
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New conjugates based on N4-hydroxycytidine with more potent antiviral efficacy in vitro than EIDD-2801 against SARS-CoV-2 and other human coronaviruses by Siniavin, Andrei E., Gushchin, Vladimir A., Shastina, Natal'ya S., Darnotuk, Elizaveta S., Luyksaar, Sergey I., Russu, Leonid I., Inshakova, Anna M., Shidlovskaya, Elena V., Vasina, Daria V., Kuznetsova, Nadezhda A., Savina, Daria M., Zorkov, Ilya D., Dolzhikova, Inna V., Sheremet, Anna B., Logunov, Denis Y., Zigangirova, Nailya A., Gintsburg, Alexander L.

“…The spread of COVID-19 continues due to genetic variation in SARS-CoV-2. Highly mutated variants of SARS-CoV-2 have an increased transmissibility and immune…”
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The influence of an innovative antibacterial drug of the thiadiazinone class on the virulence factors of bacteria of the phylum Pseudomonadota, which chronically infect patients with cystic fibrosis by Voronina, Olga L., Koroleva, Ekaterina A., Kunda, Marina S., Ryzhova, Natalia N., Aksenova, Ekaterina I., Kapotina, Lidia N., Nelubina, Stanislava A., Lazareva, Anna V., Zigangirova, Nailya A.

“…Introduction. Infections of the lower respiratory tract by bacteria of the Pseudomonadota phylum: Pseudomonas aeruginosa, Burkholderia spp., Achromobacter spp…”
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Lycopene presence in facial skin corneocytes and sebum and its association with circulating lycopene isomer profile: Effects of age and dietary supplementation by Petyaev, Ivan M., Pristensky, Dmitry V., Morgunova, Elena Y., Zigangirova, Nailya A., Tsibezov, Valeriy V., Chalyk, Natalia E., Klochkov, Victor A., Blinova, Victoria V., Bogdanova, Tatiana M., Iljin, Alexei A., Sulkovskaya, Larisa S., Chernyshova, Marina P., Lozbiakova, Marina V., Kyle, Nigel H., Bashmakov, Yuriy K.

“…Lycopene is a dietary antioxidant known to prevent skin photodamage. This study aimed to examine age‐dependent presence of this carotenoid on the surface of…”
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Chlamydia trachomatis promotes 3T3 cell differentiation into adipocytes by Petyaev, Ivan M, Zigangirova, Nailya A, Kapotina, Lydia N, Fedina, Elena D, Kyle, Nigel H

“…There is experimental and clinical evidence showing that some viral and bacterial pathogens are linked to the accumulation of excessive body fat and obesity…”
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P2-8 CHLAMYDIA INFECTION IN CARDIOVASCULAR DISEASES: SEQUEL II by Petyaev, Ivan M, Zigangirova, Nailya A

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Chlamydia trachomatis growth inhibition and restoration of LDL-receptor level in HepG2 cells treated with mevastatin by Bashmakov, Yuriy K, Zigangirova, Nailya A, Pashko, Yulia P, Kapotina, Lidia N, Petyaev, Ivan M

“…Perihepatitis is rare but consistently occurring extragenital manifestation of untreated Chlamydia trachomatis infection. Despite of possible liver involvement…”
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Chlamydia trachomatisgrowth inhibition and restoration of LDL-receptor level in HepG2 cells treated with mevastatin by Bashmakov, Yuriy K, Zigangirova, Nailya A, Pashko, Yulia P, Kapotina, Lidia N, Petyaev, Ivan M

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