Search Results - "Zientek, H."

The inverse electron demand Diels–Alder cycloaddition with carbon‐11 and fluorine‐18: A gateway to pretargeted imaging across the blood–brain barrier by Zientek, Simon H., Thompson, Stephen, Sephton, Selena Milicevic, Aigbirhio, Franklin I.

“…There is increased focus on developing tools to image large biomolecules, such as antibodies, within the brain using positron emission tomography (PET). The…”
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Potential of miRNA as Imaging Targets for PET by Zientek, Simon H., Thompson, Stephen, Aigbirhio, Franklin I., Sephton, Selena Milicevic

“…Positron Emission Tomography (PET) is an important part of the medical imaging field which is continually exploring novel biological targets as exemplified by…”
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BRCA1 and BRCA2 mutations as prognostic factors in bilateral breast cancer patients by Rogozińska-Szczepka, J., Utracka-Hutka, B., Grzybowska, E., Mąka, B., Nowicka, E., Smok-Ragankiewicz, A., Zientek, H., Steffen, J., Wojciechowska-Łącka, A.

“…Background: Incidence of primary bilateral breast cancer (BC) is rare and does not exceed 5%. BRCA1/2 mutation carriers diagnosed with breast cancer have a…”
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Vascular Endothelial Growth Factor Polymorphisms in Relation to Breast Cancer Development and Prognosis by QIANREN JIN, HEMMINKI, Kari, ZIENTEK, Helena, ROGOZINSKA-SZCZEPKA, Jadwiga, UTRACKA-HUTKA, Beata, HALLMANS, Göran, FÖRSTI, Asta, ENQUIST, Kerstin, LENNER, Per, GRZYBOWSKA, Ewa, KLAES, Rüdiger, HENRIKSSON, Roger, BOWANG CHEN, PAMULA, Jolanta, PEKALA, Wioletta

“…Purpose: Angiogenesis is a necessary step in tumor growth and metastasis. Vascular endothelial growth factor (VEGF) is a major mediator of breast cancer…”
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Germline Mutations in BRCA1 and BRCA2 in Polish Families Predisposed to Breast and Ovary Cancers by Grzybowska, E., Jasinska, A., Kozlowski, P., Zientek, H., Krzyzosiak, W., Utracka-Hutka, B., Wloch, J., Rogozinska-Szczepka, J.

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Single nucleotide polymorphisms in breast cancer by Försti, Asta, Angelini, Sabrina, Festa, Fabiola, Sanyal, Somali, Zhang, Zhenzhong, Grzybowska, Ewa, Pamula, Jolanta, Pekala, Wioletta, Zientek, Helena, Hemminki, Kari, Kumar, Rajiv

“…A limited number of genes have been identified that explain heritable risks of breast cancer (BC). We searched for low-penetrant genes in an association study…”
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Polymorphisms in the IGF-1 and IGFBP3 promoter and the risk of breast cancer by WAGNER, Kerstin, HEMMINKI, Kari, FÖRSTIL, Asia, ISRAELSSON, Elisabeth, GRZYBOWSKA, Ewa, SÖDERBERG, Magnus, PAMULA, Jolanta, PEKALA, Wioletta, ZIENTEK, Helena, MIELZYNSKA, Danuta, SIWINSKA, Ewa

“…Binding of IGF-1 to the type I IGF receptor starts a signalling cascade that plays an important role in regulating cell proliferation, differentiation and…”
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Association of NCOA3 Polymorphisms with Breast Cancer Risk by BURWINKEL, Barbara, WIRTENBERGER, Michael, BUTKIEWICZ, Dorota, PAMULA, Jolanta, PEKALA, Wioletta, ZIENTEK, Helena, MIELZYNSKA, Danuta, SIWINSKA, Ewa, BARTRAM, Claus R, HEMMINKI, Kari, KLAES, Rüdiger, SCHMUTZLER, Rita K, GRZYBOWSKA, Ewa, FÖRSTI, Asta, FRANK, Bernd, BERMEJO, Justo Lorenzo, BUGERT, Peter, WAPPENSCHMIDT, Barbara

“…The nuclear receptor coactivator 3 ( NCOA3 , also known as AIB1 ) is a coactivator of nuclear receptors like the estrogen receptor. NCOA3 is overexpressed in…”
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The insulin-like growth factor-1 pathway mediator genes: SHC1 Met300Val shows a protective effect in breast cancer by Wagner, Kerstin, Hemminki, Kari, Grzybowska, Ewa, Klaes, Rüdiger, Butkiewicz, Dorota, Pamula, Jolanta, Pekala, Wioletta, Zientek, Helena, Mielzynska, Danuta, Siwinska, Ewa, Försti, Asta

“…The insulin-like growth factor 1 (IGF-1) pathway plays an important role in regulating cell proliferation, differentiation and apoptosis. IRS1, IRS2 and SHC1…”
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Sex hormone-binding globulin polymorphisms in familial and sporadic breast cancer by Försti, Asta, Jin, Qianren, Grzybowska, Ewa, Söderberg, Magnus, Zientek, Helena, Sieminska, Marzena, Rogozinska-Szczepka, Jadwiga, Chmielik, Ewa, Utracka-Hutka, Beata, Hemminki, Kari

“…Ovarian steroids are one of the strongest risk factors for breast cancer. Sex hormone-binding globulin (SHBG) binds and transports sex steroids in the blood,…”
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Polyglutamine repeat length in the NCOA3 does not affect risk in familial breast cancer by WILKENING, Stefan, BURWINKEL, Barbara, GRZYBOWSKA, Ewa, KLAES, Rüdiger, PAMULA, Jolanta, PEKALA, Wioletta, ZIENTEK, Helena, HEMMINKI, Kari, FÖRSTI, Asta

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Identification of novel sequence alterations and the functional analysis of the BRCA1 promoter/5'-UTR in families from Upper Silesia, Poland by PamuÅa, J, KrzeÅniak, M, Zientek, H, PÄkala, WP, Rusin, M, Grzybowska, E

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c‐MYC Asn11Ser is associated with increased risk for familial breast cancer by Wirtenberger, Michael, Hemminki, Kari, Försti, Asta, Klaes, Rüdiger, Schmutzler, Rita K., Grzybowska, Ewa, Bermejo, Justo L., Wappenschmidt, Barbara, Bugert, Peter, Butkiewicz, Dorota, Pamula, Jolanta, Pekala, Wioletta, Zientek, Helena, Bartram, Claus R., Burwinkel, Barbara

“…c‐MYC is a multifaceted protein that regulates cell proliferation, differentiation and apoptosis. Its crucial role in diverse cancers has been demonstrated in…”
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High frequency of recurrent mutations in BRCA1 and BRCA2 genes in Polish families with breast and ovarian cancer by Grzybowska, Ewa, Zientek, Helena, Jasinska, Anna, Rusin, Marek, Kozlowski, Piotr, Sobczak, Krzysztof, Sikorska, Anna, Kwiatkowska, Eliza, Gorniak, Laura, Kalinowska, Ewa, Utracka-Hutka, Beata, Wloch, Jan, Chmielik, Ewa, Krzyzosiak, Wlodzimierz J.

“…Germ‐line mutations in BRCA1 and BRCA2 genes result in a significantly increased risk of breast and ovarian cancer. Other genes involved in an increased…”
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Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk by Rusin, Marek, Zientek, Helena, Krześniak, Małgorzata, Małusecka, Ewa, Zborek, Anna, Krzyżowska-Gruca, Stefania, Butkiewicz, Dorota, Vaitiekunaite, Rasa, Lisowska, Katarzyna, Grzybowska, Ewa, Krawczyk, Zdzisław

“…Somatic mutations of 11q23.3‐linked constitutive heat shock protein 70 gene (HSPA8 alias HSC70) are detected by others in breast carcinomas. To examine whether…”
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Polymorphisms in the IGF-1 and IGFBP 3 promoter and the risk of breast cancer by Wagner, Kerstin, Hemminki, Kari, Israelsson, Elisabeth, Grzybowska, Ewa, Söderberg, Magnus, Pamula, Jolanta, Pekala, Wioletta, Zientek, Helena, Mielzynska, Danuta, Siwinska, Ewa, Försti, Asta

“…Binding of IGF-1 to the type I IGF receptor starts a signalling cascade that plays an important role in regulating cell proliferation, differentiation and…”
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Polymorphisms and haplotype structures in genes for transforming growth factor beta1 and its receptors in familial and unselected breast cancers by Jin, Qianren, Hemminki, Kari, Grzybowska, Ewa, Klaes, Rüdiger, Söderberg, Magnus, Zientek, Helena, Rogozinska-Szczepka, Jadwiga, Utracka-Hutka, Beata, Pamula, Jolanta, Pekala, Wioletta, Försti, Asta

“…Alterations in TGF-beta signaling appear to be associated with an altered risk of developing cancer, including breast cancer. We carried out a case-control…”
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Germline mutations in the BRCA1 gene predisposing to breast and ovarian cancers in Upper Silesia population by Grzybowska, Ewa, Siemińska, Marzena, Zientek, Helena, Kalinowska, Ewa, Michalska, Jadwiga, Utracka-Hutka, Beata, Rogozińska-Szczepka, Jadwiga, Kaźmierczak-Maciejewska, Maria

“…Germline mutations in the BRCA1 or BRCA2 genes predispose their carriers to breast or/and ovary cancers during their lifetime. The most frequent mutations:…”
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Association of NCOA3 (AIB1) polymorphisms with breast cancer risk by Burwinkel, B, Wirtenberger, M, Frank, B, Klaes, R, Schmutzler, RK, Grzybowska, E, Försti, A, Bermejo, JL, Bugert, P, Wappenschmidt, B, Butkiewicz, D, Pamula, J, Pekala, W, Zientek, H, Mielzynska, D, Siwinska, E, Bartram, CR, Hemminki, K

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BRCA1, BRCA2 and TP53 mutations among breast cancer families from upper silesia in Poland by Zientek, H., Jasinska, A., Rusin, M., Kozlowski, P., Sikorska, A., Kwiatkowska, E., Kalinowska, E., Sobczak, K., Krzyzosiak, W., Grzybowska, E.

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