Search Results - "Ziegler, Steven"

TSLP: from allergy to cancer by Corren, Jonathan, Ziegler, Steven F.

“…The cytokine TSLP has been shown to be a key factor in maintaining immune homeostasis and regulating inflammatory responses at mucosal barriers. While the role…”
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Epithelial cell-derived cytokines: more than just signaling the alarm by Roan, Florence, Obata-Ninomiya, Kazushige, Ziegler, Steven F

“…The epithelial cell-derived cytokines thymic stromal lymphopoietin (TSLP), IL-33, and IL-25 are central regulators of type 2 immunity, which drives a broad…”
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The atopic march: current insights into skin barrier dysfunction and epithelial cell‐derived cytokines by Han, Hongwei, Roan, Florence, Ziegler, Steven F.

“…Summary Atopic dermatitis often precedes the development of other atopic diseases. The atopic march describes this temporal relationship in the natural history…”
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Thymic stromal lymphopoietin and allergic disease by Ziegler, Steven F., PhD

“…The importance of the epithelium in initiating and controlling immune responses is becoming more appreciated. For example, allergen contact first occurs at…”
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FOXP3: of mice and men by Ziegler, Steven F

“…The immune system has evolved mechanisms to recognize and eliminate threats, as well as to protect against self-destruction. Tolerance to self-antigens is…”
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FOXP3 and scurfy: how it all began by Ramsdell, Fred, Ziegler, Steven F.

“…The molecular cloning of the forkhead box P3 ( FOXP3 ) gene led to a renaissance in the field of suppressor T cells (now known as regulatory T cells). In this…”
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Sensing the outside world: TSLP regulates barrier immunity by Ziegler, Steven F, Artis, David

“…Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and…”
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Thymic stromal lymphopoietin, skin barrier dysfunction, and the atopic march by Ziegler, Steven F.

“…Atopic dermatitis often precedes the development of other atopic diseases, and the atopic march describes this temporal relationship in the natural history of…”
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The role of thymic stromal lymphopoietin (TSLP) in allergic disorders by Ziegler, Steven F

“…The importance of the epithelium in initiating and controlling immune responses is becoming more appreciated. For example, allergen contact first occurs at…”
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A tumor–myeloid cell axis, mediated via the cytokines IL-1α and TSLP, promotes the progression of breast cancer by Kuan, Emma L., Ziegler, Steven F.

“…Tumors actively manipulate the immune response through the production of factors that attract immune cells and subsequently alter their ability to recognize…”
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Division of labour by CD4+ T helper cells by Ziegler, Steven F.

“…Steven Ziegler describes a 1986 study by Mossmann et al . that defined two subsets of T helper cells on the basis of their activities…”
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FOXP3: Not just for regulatory T cells anymore by Ziegler, Steven F.

“…The forkhead family transcription factor FOXP3 has been shown to be critical for the development and function of CD4+CD25+ regulatory T cells. Recently, FOXP3…”
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Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection by Norris, Geoffrey T, Ames, Joshua M, Ziegler, Steven F, Oberst, Andrew

“…In order to recover from infection, organisms must balance robust immune responses to pathogens with the tolerance of immune-mediated pathology. This balance…”
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Cross-Talk Between Alveolar Macrophages and Lung Epithelial Cells is Essential to Maintain Lung Homeostasis by Bissonnette, Elyse Y, Lauzon-Joset, Jean-François, Debley, Jason S, Ziegler, Steven F

“…The main function of the lung is to perform gas exchange while maintaining lung homeostasis despite environmental pathogenic and non-pathogenic elements…”
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Thymic stromal lymphopoietin signaling in B cells from progenitors to plasma cells by Domeier, Phillip P, Ziegler, Steven F

“…Thymic stromal lymphopoietin (TSLP) is an established pleotropic alarmin cytokine that is generated at barrier tissues to induce type 2 immune responses, but…”
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TSLP drives acute TH2-cell differentiation in lungs by Lai, Jen-Feng, Thompson, Lucas J., Ziegler, Steven F.

“…Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine that is important for the development of type 2 inflammatory responses at mucosal…”
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Cutting edge: identification of the thymic stromal lymphopoietin-responsive dendritic cell subset critical for initiation of type 2 contact hypersensitivity by Kitajima, Masayuki, Ziegler, Steven F

“…The cytokine thymic stromal lymphopoietin (TSLP) has been implicated in the initiation and progression of allergic inflammation through its ability to activate…”
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The biology of thymic stromal lymphopoietin (TSLP) by Ziegler, Steven F, Roan, Florence, Bell, Bryan D, Stoklasek, Thomas A, Kitajima, Masayuki, Han, Hongwei

“…Originally shown to promote the growth and activation of B cells, thymic stromal lymphopoietin (TSLP) is now known to have wide-ranging impacts on both…”
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Investigating Thymic Epithelial Cell Diversity Using Systems Biology by Chiu, Honyin, Linsley, Peter S, Ziegler, Steven F

“…The thymus is an intricate organ consisting of a diverse population of thymic epithelial cells (TECs). Cortical and medullary TECs and their subpopulations…”
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ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation by Leyva-Castillo, Juan Manuel, Galand, Claire, Mashiko, Shunya, Bissonnette, Robert, McGurk, Alex, Ziegler, Steven F., Dong, Chen, McKenzie, Andrew N.J., Sarfati, Marika, Geha, Raif S.

“…Atopic dermatitis skin lesions demonstrate increased expression of IL-25 by keratinocytes and increased numbers of type 2 innate lymphoid cells (ILC2s) that…”
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