Search Results - "Zieba, Bartosz J."

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1) by Zak, Krzysztof M, Grudnik, Przemyslaw, Guzik, Katarzyna, Zieba, Bartosz J, Musielak, Bogdan, Dömling, Alexander, Dubin, Grzegorz, Holak, Tad A

“…Targeting the PD-1/PD-L1 immunologic checkpoint with monoclonal antibodies has provided unprecedented results in cancer treatment in the recent years…”
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Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor by Carlson, David A, Franke, Aaron S, Weitzel, Douglas H, Speer, Brittany L, Hughes, Philip F, Hagerty, Laura, Fortner, Christopher N, Veal, James M, Barta, Thomas E, Zieba, Bartosz J, Somlyo, Avril V, Sutherland, Cindy, Deng, Jing Ti, Walsh, Michael P, MacDonald, Justin A, Haystead, Timothy A. J

“…DAPK1 and ZIPK (also called DAPK3) are closely related serine/threonine protein kinases that regulate programmed cell death and phosphorylation of non-muscle…”
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The actin associated protein palladin is important for the early smooth muscle cell differentiation by Jin, Li, Gan, Qiong, Zieba, Bartosz J, Goicoechea, Silvia M, Owens, Gary K, Otey, Carol A, Somlyo, Avril V

“…Palladin, an actin associated protein, plays a significant role in regulating cell adhesion and cell motility. Palladin is important for development, as…”
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The cAMP-responsive Rap1 Guanine Nucleotide Exchange Factor, Epac, Induces Smooth Muscle Relaxation by Down-regulation of RhoA Activity by Zieba, Bartosz J., Artamonov, Mykhaylo V., Jin, Li, Momotani, Ko, Ho, Ruoya, Franke, Aaron S., Neppl, Ronald L., Stevenson, Andra S., Khromov, Alexander S., Chrzanowska-Wodnicka, Magdalena, Somlyo, Avril V.

“…Agonist activation of the small GTPase, RhoA, and its effector Rho kinase leads to down-regulation of smooth muscle (SM) myosin light chain phosphatase…”
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Rap1b in Smooth Muscle and Endothelium Is Required for Maintenance of Vascular Tone and Normal Blood Pressure by Lakshmikanthan, Sribalaji, Zieba, Bartosz J, Ge, Zhi-Dong, Momotani, Ko, Zheng, Xiaodong, Lund, Hayley, Artamonov, Mykhaylo V, Maas, Jason E, Szabo, Aniko, Zhang, David X, Auchampach, John A, Mattson, David L, Somlyo, Avril V, Chrzanowska-Wodnicka, Magdalena

“…OBJECTIVE—Small GTPase Ras-related protein 1 (Rap1b) controls several basic cellular phenomena, and its deletion in mice leads to several cardiovascular…”
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Abstract 206: Small GTPase Rap1 Transmits Mechanical Signals to Control Vascular Tone and Blood Pressure by Lakshmikanthan, Sribalaji, Zheng, Xiaodong, Zieba, Bartosz J, Nishijima, Yoshinori, Ge, Zhi-Dong, Momotani, Ko, Lund, Hayley, Maas, Jason E, Szabo, Aniko, Vasquez-Vivar, Jeannette, Mattson, David L, Auchampach, John A, Somlyo, Avril V, Zhang, David X, Chrzanowska-Wodnicka, Magdalena

“…Abstract only Smooth muscle (SM)-mediated vessel contraction and endothelium-dependent vessel dilation are major mechanisms controlling basal vascular tone…”
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Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G 0 /G 1 Arrest by Inhibiting Deubiquitinase USP2a by Magiera, Katarzyna, Tomala, Marcin, Kubica, Katarzyna, De Cesare, Virginia, Trost, Matthias, Zieba, Bartosz J, Kachamakova-Trojanowska, Neli, Les, Marcin, Dubin, Grzegorz, Holak, Tad A, Skalniak, Lukasz

“…USP2a is a deubiquitinase responsible for stabilization of cyclin D1, a crucial regulator of cell-cycle progression and a proto-oncoprotein overexpressed in…”
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