Search Results - "Zick, Y."

Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance by Zick, Y

“…Insulin resistance refers to a decreased capacity of circulating insulin to regulate nutrient metabolism. Recent studies reveal that agents that induce insulin…”
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Periparturient dairy cows do not exhibit hepatic insulin resistance, yet adipose-specific insulin resistance occurs in cows prone to high weight loss by Zachut, M, Honig, H, Striem, S, Zick, Y, Boura-Halfon, S, Moallem, U

“…The periparturient period in dairy cows is associated with alterations in insulin action in peripheral tissues; however, the molecular mechanism underlying…”
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Prolonged insulin treatment sensitizes apoptosis pathways in pancreatic β cells by Bucris, E, Beck, A, Boura-Halfon, S, Isaac, R, Vinik, Y, Rosenzweig, T, Sampson, S R, Zick, Y

“…Insulin resistance results from impaired insulin signaling in target tissues that leads to increased levels of insulin required to control plasma glucose…”
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Arbitration and Stability in Cooperative Games with Overlapping Coalitions by Zick, Y., Markakis, E., Elkind, E.

“…Overlapping Coalition Formation (OCF) games, introduced by Chalkiadakis, Elkind, Markakis, Polukarov and Jennings in 2010, are cooperative games where players…”
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Otubain 2 is a novel promoter of beta cell survival as revealed by siRNA high-throughput screens of human pancreatic islets by Beck, A., Vinik, Y., Shatz-Azoulay, H., Isaac, R., Streim, S., Jona, G., Boura-Halfon, S., Zick, Y.

“…Aims/hypothesis Pro-inflammatory cytokines induce death of beta cells and hamper engraftment of transplanted islet mass. Our aim was to reveal novel genes…”
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Hepatitis C core protein impairs insulin downstream signalling and regulatory role of IGFBP-1 expression by Alberstein, M., Zornitzki, T., Zick, Y., Knobler, H.

“…Chronic infection with hepatitis C virus (HCV), mainly genotype 1, has been shown to be associated with insulin resistance and type 2 diabetes. The mechanisms…”
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Role of Ser/Thr kinases in the uncoupling of insulin signaling by Zick, Y

“…Insulin resistance refers to a decreased capacity of circulating insulin to regulate nutrient metabolism. It is associated with the development of type II…”
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An siRNA screen identifies transmembrane 7 superfamily member 3 (TM7SF3), a seven transmembrane orphan receptor, as an inhibitor of cytokine-induced death of pancreatic beta cells by Beck, A., Isaac, R., Lavelin, I., Hart, Y., Volberg, T., Shatz-Azoulay, H., Geiger, B., Zick, Y.

“…Aims/hypothesis Pro-inflammatory cytokines induce death of pancreatic beta cells, leading to the development of type 1 diabetes. We sought to identify novel…”
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Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis by Hadari, Y R, Arbel-Goren, R, Levy, Y, Amsterdam, A, Alon, R, Zakut, R, Zick, Y

“…The interaction of cells with the extracellular matrix regulates cell adhesion, motility, growth, survival and differentiation through integrin-mediated signal…”
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An siRNA screen identifies transmembrane 7 superfamily member 3 (TM7SF3), a seven transmembrane orphan receptor, as an inhibitor of cytokine-induced death of pancreatic beta cells by BECK, A, ISAAC, R, LAVELIN, I, HART, Y, VOLBERG, T, SHATZ-AZOULAY, H, GEIGER, B, ZICK, Y

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The effect of tyrosine‐specific protein phosphorylation on the assembly of adherens‐type junctions by Volberg, T., Zick, Y., Dror, R., Sabanay, I., Gilon, C., Levitzki, A., Geiger, B.

“…Adherens‐type junctions (AJs) are major subcellular targets for tyrosine specific protein phosphorylation [Volberg et al. (1991) Cell Regul., 2, 105–120]. Here…”
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Expression and putative role of lactoseries carbohydrates present on NCAM in the rat primary olfactory pathway by Storan, Melonie Joanne, Magnaldo, Thierry, Biol-N'Garagba, Marie-Claire, Zick, Yehiel, Key, Brian

“…Primary olfactory neurons project axons from the olfactory neuroepithelium lining the nasal cavity to the olfactory bulb in the brain. These axons grow within…”
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The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells by HEFFETZ, D, BUSHKIN, I, DROR, R, ZICK, Y

“…H2O2 and vanadate are known insulinomimetic agents. Together they induce insulin's bioeffects with a potency which exceeds that seen with insulin, vanadate, or…”
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Combined analysis of tumor growth pattern and expression of endogenous lectins as a prognostic tool in primary testicular cancer and its lung metastases by Kayser, K, Hoeft, D, Hufnagi, P, Caselitz, J, Zick, Y, André, S, Kaltner, H, Gabius, H-J

“…The aim of this study was to glyco- and immunohistochemically analyze expression of distinct growth/adhesion-related markers of primary testicular carcinomas…”
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Galectin fingerprinting by immuno- and lectin histochemistry in cutaneous lymphoma by WOLLINA, U, GRAEFE, T, FELDRAPPE, S, ANDRE, S, WASANO, K, KALTNER, H, ZICK, Y, GABIUS, H.-J

“…Owing to their relevance for growth regulation and cell adhesion monitoring the expression of galectins (endogenous beta-galactoside-binding lectins) and their…”
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Elevated protein tyrosine phosphatase activity and increased membrane viscosity are associated with impaired activation of the insulin receptor kinase in old rats by NADIV, O, SHINITZKY, M, MANU, H, HECHT, D, ROBERTS, C. T, LEROITH, D, ZICK, Y

“…Insulin resistance is very common in the elderly, and may be associated with glucose intolerance or frank diabetes. In previous studies we demonstrated that…”
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H2O2 potentiates phosphorylation of novel putative substrates for the insulin receptor kinase in intact Fao cells by Heffetz, D, Zick, Y

“…Western blotting with anti-phosphotyrosine antibodies was employed in order to study insulin-dependent protein tyrosine phosphorylation in intact Fao cells. In…”
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The insulinomimetic agents H2O2 and vanadate stimulate tyrosine phosphorylation of potential target proteins for the insulin receptor kinase in intact cells by HEFFETZ, D, RUTTER, W. J, ZICK, Y

“…H2O2 and vanadate are known insulinomimetic agents. Together they induce insulin's bioeffects with a potency which exceeds that seen with insulin, vanadate or…”
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Insulin resistance: a phosphorylation-based uncoupling of insulin signaling by Zick, Y

“…Insulin resistance refers to a decreased capacity of circulating insulin to regulate nutrient metabolism. It is associated with the development of type 2…”
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The Insulin-Like Growth Factor I Receptor-Induced Interaction of Insulin Receptor Substrate-4 and Crk-II by Karas, M, Koval, A. P, Zick, Y, LeRoith, D

“…Stimulation of the insulin or insulin-like growth factor (IGF)-I receptor results in activation of several signaling pathways. Proteins of the insulin receptor…”
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