Search Results - "Zick, Aviad"

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease by Moss, Joshua, Magenheim, Judith, Neiman, Daniel, Zemmour, Hai, Loyfer, Netanel, Korach, Amit, Samet, Yaacov, Maoz, Myriam, Druid, Henrik, Arner, Peter, Fu, Keng-Yeh, Kiss, Endre, Spalding, Kirsty L., Landesberg, Giora, Zick, Aviad, Grinshpun, Albert, Shapiro, A. M. James, Grompe, Markus, Wittenberg, Avigail Dreazan, Glaser, Benjamin, Shemer, Ruth, Kaplan, Tommy, Dor, Yuval

“…Methylation patterns of circulating cell-free DNA (cfDNA) contain rich information about recent cell death events in the body. Here, we present an approach for…”
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Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing by Katsman, Efrat, Orlanski, Shari, Martignano, Filippo, Fox-Fisher, Ilana, Shemer, Ruth, Dor, Yuval, Zick, Aviad, Eden, Amir, Petrini, Iacopo, Conticello, Silvestro G, Berman, Benjamin P

“…The Oxford Nanopore (ONT) platform provides portable and rapid genome sequencing, and its ability to natively profile DNA methylation without complex sample…”
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ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin by Sadeh, Ronen, Sharkia, Israa, Fialkoff, Gavriel, Rahat, Ayelet, Gutin, Jenia, Chappleboim, Alon, Nitzan, Mor, Fox-Fisher, Ilana, Neiman, Daniel, Meler, Guy, Kamari, Zahala, Yaish, Dayana, Peretz, Tamar, Hubert, Ayala, Cohen, Jonathan E., Salah, Azzam, Temper, Mark, Grinshpun, Albert, Maoz, Myriam, Abu-Gazala, Samir, Ben Ya’acov, Ami, Shteyer, Eyal, Safadi, Rifaat, Kaplan, Tommy, Shemer, Ruth, Planer, David, Galun, Eithan, Glaser, Benjamin, Zick, Aviad, Dor, Yuval, Friedman, Nir

“…Cell-free DNA (cfDNA) in human plasma provides access to molecular information about the pathological processes in the organs or tumors from which it…”
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Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes by Sherill-Rofe, Dana, Rahat, Dolev, Findlay, Steven, Mellul, Anna, Guberman, Irene, Braun, Maya, Bloch, Idit, Lalezari, Alon, Samiei, Arash, Sadreyev, Ruslan, Goldberg, Michal, Orthwein, Alexandre, Zick, Aviad, Tabach, Yuval

“…The homologous recombination repair (HRR) pathway repairs DNA double-strand breaks in an error-free manner. Mutations in HRR genes can result in increased…”
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Temporal trends of geographic variation in mortality following cancer diagnosis: a population-based study by Rottenberg, Yakir, Zick, Aviad, Levine, Hagai

“…Inequalities among the western population, combined with the introduction of new treatment options for cancer, have challenged endeavors to provide equal care…”
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Short report: Plasma based biomarkers detect radiation induced brain injury in cancer patients treated for brain metastasis: A pilot study by Makranz, Chen, Lubotzky, Asael, Zemmour, Hai, Shemer, Ruth, Glaser, Benjamin, Cohen, Jonathan, Maoz, Myriam, Sapir, Eli, Wygoda, Marc, Peretz, Tamar, Weizman, Noam, Feldman, Jon, Abrams, Ross A, Lossos, Alexander, Dor, Yuval, Zick, Aviad

“…Background Radiotherapy has an important role in the treatment of brain metastases but carries risk of short and/or long-term toxicity, termed…”
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The Role of Methionine Aminopeptidase 2 in Lymphangiogenesis by Esa, Rawnaq, Steinberg, Eliana, Dror, Dvir, Schwob, Ouri, Khajavi, Mehrdad, Maoz, Miriam, Kinarty, Yael, Inbal, Adi, Zick, Aviad, Benny, Ofra

“…During the metastasis process, tumor cells invade the blood circulatory system directly from venous capillaries or indirectly via lymphatic vessels…”
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Author Correction: ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin by Sadeh, Ronen, Sharkia, Israa, Fialkoff, Gavriel, Rahat, Ayelet, Gutin, Jenia, Chappleboim, Alon, Nitzan, Mor, Fox-Fisher, Ilana, Neiman, Daniel, Meler, Guy, Kamari, Zahala, Yaish, Dayana, Peretz, Tamar, Hubert, Ayala, Cohen, Jonathan E., Salah, Azzam, Temper, Mark, Grinshpun, Albert, Maoz, Myriam, Abu-Gazala, Samir, Ben Ya’acov, Ami, Shteyer, Eyal, Safadi, Rifaat, Kaplan, Tommy, Shemer, Ruth, Planer, David, Galun, Eithan, Glaser, Benjamin, Zick, Aviad, Dor, Yuval, Friedman, Nir

“…A Correction to this paper has been published: https://doi.org/10.1038/s41587-021-00831-9…”
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Author Correction: ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin by Sadeh, Ronen, Sharkia, Israa, Fialkoff, Gavriel, Rahat, Ayelet, Gutin, Jenia, Chappleboim, Alon, Nitzan, Mor, Fox-Fisher, Ilana, Neiman, Daniel, Meler, Guy, Kamari, Zahala, Yaish, Dayana, Peretz, Tamar, Hubert, Ayala, Cohen, Jonathan E., Salah, Azzam, Temper, Mark, Grinshpun, Albert, Maoz, Myriam, Abu-Gazala, Samir, Ben Ya’acov, Ami, Shteyer, Eyal, Safadi, Rifaat, Kaplan, Tommy, Shemer, Ruth, Planer, David, Galun, Eithan, Glaser, Benjamin, Zick, Aviad, Dor, Yuval, Friedman, Nir

“…A Correction to this paper has been published: https://doi.org/10.1038/s41587-021-00853-3…”
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Clinical Implications of Sub-grouping HER2 Positive Tumors by Amplicon Structure and Co-amplified Genes by Maoz, Myriam, Devir, Michal, Inbar, Michal, Inbar-Daniel, Ziva, Sherill-Rofe, Dana, Bloch, Idit, Meir, Karen, Edelman, David, Azzam, Salah, Nechushtan, Hovav, Maimon, Ofra, Uziely, Beatrice, Kadouri, Luna, Sonnenblick, Amir, Eden, Amir, Peretz, Tamar, Zick, Aviad

“…ERBB2 amplification is a prognostic marker for aggressive tumors and a predictive marker for prolonged survival following treatment with HER2 inhibitors. We…”
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"High-Risk Breast Cancer Screening in BRCA1/2 Carriers Leads to Early Detection and Improved Survival After a Breast Cancer Diagnosis" by Shraga, Shay, Grinshpun, Albert, Zick, Aviad, Kadouri, Luna, Cohen, Yogev, Maimon, Ofra, Adler-Levy, Yael, Zeltzer, Galina, Granit, Avital, Maly, Bella, Carmon, Einat, Meiner, Vardiella, Sella, Tamar, Hamburger, Tamar, Peretz, Tamar

“…Germline pathogenic variant (PV) carriers have high lifetime risk of developing breast cancer and therefore subjected to intense lifetime screening. However,…”
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First Female Patient with a Rare CIC-FOXO4-Translocated Sarcoma: A Case Report by Babkoff, Aryeh, Berner-Wygoda, Yael, Diment, Judith, Kustanovich, Anatoli, Zick, Aviad, Katz, Daniela, Grinshpun, Albert

“…Abstract Small round cell sarcoma is a group of undifferentiated malignancies arising in the bone and soft tissue, notable for Ewing sarcoma. Recently, a new…”
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Author Correction: Clinical Implications of Sub-grouping HER2 Positive Tumors by Amplicon Structure and Co-amplified Genes by Maoz, Myriam, Devir, Michal, Inbar, Michal, Inbar-Daniel, Ziva, Sherill-Rofe, Dana, Bloch, Idit, Meir, Karen, Edelman, David, Azzam, Salah, Nechushtan, Hovav, Maimon, Ofra, Uziely, Beatrice, Kadouri, Luna, Sonnenblick, Amir, Eden, Amir, Peretz, Tamar, Zick, Aviad

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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A clinical evaluation of an ex vivo organ culture system to predict patient response to cancer therapy by Golan, Shay, Bar, Vered, Salpeter, Seth J., Neev, Guy, Creiderman, German, Kedar, Daniel, Aharon, Sara, Turovsky, Lubov, Zundelevich, Adi, Shahar, Hamutal, Shapira, Hagit, Mallel, Giuseppe, Stossel, Erez, Gavert, Nancy, Straussman, Ravid, Dotan, Zohar, Berger, Raanan, Stossel, Chani, Golan, Talia, Halperin, Sharon, Leibovici, Dan, Breuer, Shani, Rottenberg, Yakir, Applebaum, Liat, Hubert, Ayala, Nechushtan, Hovav, Peretz, Tamar, Zick, Aviad, Chertin, Boris, Koulikov, Dmitry, Sonnenblick, Amir, Rosenbaum, Eli

“…IntroductionEx vivo organ cultures (EVOC) were recently optimized to sustain cancer tissue for 5 days with its complete microenvironment. We examined the…”
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Residence near industrial complex and cancer incidence: A registry-based cohort of 1,022,637 participants with a follow-up of 21 years, Israel by Kayyal-Tarabeia, Inass, Blank, Michael, Zick, Aviad, Agay-Shay, Keren

“…Industrial complex (IC) residence is associated with higher cancer incidence in adults and children. However, the effect on young adults and the residence…”
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Beyond lung cancer: air pollution and bladder, breast and prostate cancer incidence by Kayyal-Tarabeia, Inass, Zick, Aviad, Kloog, Itai, Levy, Ilan, Blank, Michael, Agay-Shay, Keren

“…Abstract Background The carcinogenicity of air pollution and its impact on the risk of lung cancer is well known; however, there are still knowledge gaps and…”
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Alpelisib in Intractable Non–Islet-Cell Tumor Hypoglycemia by Cahn, Avivit, Shoyhet-Smoilovsky, Hagit, Fischer, Matan, Zick, Aviad, Riahi, Yael, Levenberg, Shulamit, Leibowitz, Gil

“…This letter describes the use of alpelisib, a PI3 kinase inhibitor, to successfully treat severe hypoglycemia in a patient with intractable non–islet-cell…”
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Clinical and molecular characterization of HER2-low metastatic colorectal cancer by Babkoff, Aryeh, Keidar Haran, Tal, Zick, Aviad, Hubert, Ayala, Grinshpun, Albert

“…e15573 Background: HER2 is a well-established biomarker and target in multiple tumor types, including metastatic colorectal cancer (mCRC). Despite the lack of…”
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Homologous recombination in lung cancer, germline and somatic mutations, clinical and phenotype characterization by Kadouri, Luna, Rottenberg, Yakir, Zick, Aviad, Hamburger, Tamar, Lipson, Doron, Peretz, Tamar, Nechushtan, Hovav

“…•Biomarkers for homologous recombination deficiency suggest high response rate to cisplatinum.•High response rate and overall survival were observed in BRCA1/2…”
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A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer by Polak, Paz, Kim, Jaegil, Braunstein, Lior Z, Karlic, Rosa, Haradhavala, Nicholas J, Tiao, Grace, Rosebrock, Daniel, Livitz, Dimitri, Kübler, Kirsten, Mouw, Kent W, Kamburov, Atanas, Maruvka, Yosef E, Leshchiner, Ignaty, Lander, Eric S, Golub, Todd R, Zick, Aviad, Orthwein, Alexandre, Lawrence, Michael S, Batra, Rajbir N, Caldas, Carlos, Haber, Daniel A, Laird, Peter W, Shen, Hui, Ellisen, Leif W, D'Andrea, Alan D, Chanock, Stephen J, Foulkes, William D, Getz, Gad

“…Paz Polak, Jaegil Kim, Lior Z. Braunstein and colleagues have identified patterns of genome-wide mutation in certain breast cancers that can be used to…”
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