Search Results - "Zibat, A."

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma by Zibat, A, Missiaglia, E, Rosenberger, A, Pritchard-Jones, K, Shipley, J, Hahn, H, Fulda, S

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and comprises two major histological subtypes: alveolar rhabdomyosarcoma (ARMS) and…”
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Imatinib‐induced complete and long‐term sustained remission in chemotherapy‐resistant systemic ALK‐positive anaplastic large cell lymphoma by Pichler, A., Kornauth, C., Garces‐de‐los‐Fayos‐Alonso, I., Kazianka, L., Alachram, H., Zibat, A., Pemovska, T., Heller, G., Greil, R., Kenner, L., Jäger, U., Staber, P.

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The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments by Rabus, R., Ruepp, A., Frickey, T., Rattei, T., Fartmann, B., Stark, M., Bauer, M., Zibat, A., Lombardot, T., Becker, I., Amann, J., Gellner, K., Teeling, H., Leuschner, W. D., Glöckner, F.-O., Lupas, A. N., Amann, R., Klenk, H.-P.

“…Summary Desulfotalea psychrophila is a marine sulfate‐reducing δ‐proteobacterium that is able to grow at in situ temperatures below 0°C. As abundant members of…”
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Laing distal myopathy with a novel mutation in exon 34 of the MYH7 gene by Ferbert, A, Zibat, A, Rautenstrauß, B, Kress, W, Hügens-Penzel, M, Weis, J, Shah, Y, Roth, C

“…Highlights • We describe a new mutation in a four generation family with Laing myopathy in MYH7. • There was complete segregaton between clinical and MRI signs…”
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Uncommitted precursor cells might contribute to increased incidence of embryonal rhabdomyosarcoma in heterozygous Patched1-mutant mice by Nitzki, F, Zibat, A, Frommhold, A, Schneider, A, Schulz-Schaeffer, W, Braun, T, Hahn, H

“…Embryonal rhabdomyosarcoma (ERMS) is a tumor of the skeletal muscle in children and is frequently initiated by heterozygous germline mutations in the Hedgehog…”
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Evaluating the effect of spastin splice mutations by quantitative allele-specific expression assay by Klimpe, S., Zibat, A., Zechner, U., Wellek, B., Shoukier, M., Sauter, S. M., Pantakani, D. V. K., Mannan, A. U.

“…Background:  Mutations in the SPG4/SPAST gene are the most common cause for hereditary spastic paraplegia (HSP). The splice‐site mutations make a significant…”
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Rapid access to genes of biotechnologically useful enzymes by partial genome sequencing: the thermoalkaliphile Anaerobranca gottschalkii by Antranikian, G, Ruepp, A, Gordon, P M K, Ballschmiter, M, Zibat, A, Stark, M, Sensen, C W, Frishman, D, Liebl, W, Klenk, H-P

“…Anaerobranca gottschalkii strain LBS3 T is an extremophile living at high temperature (up to 65 degrees C) and in alkaline environments (up to pH 10.5). An…”
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Efficient transformation of Halobacterium salinarum by a "freeze and thaw" technique by Zibat, A

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Dysfunctional crosstalk of cardiomyocytes and cardiac fibroblasts in a pluripotent stem cell model of dilated cardiomyopathy by Maurer, W, Koehne, S, Maus, A, Tiburcy, M, Schlick, S, Zibat, A, Zimmermann, W.H, Sossalla, S, Wollnik, B, Streckfuss-Boemeke, K

“…Abstract Background/Purpose Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation and contractile dysfunction. Fibrosis is one major…”
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The genetic determinants of the CYP3A5 polymorphism by HUSTERT, Elisabeth, HABERL, Michael, KOCH, Ina, ZIBAT, Arne, BROCKMÖLLER, Jürgen, HALPERT, James R, ZANGER, Ulrich M, WOJNOWSKI, Leszek, BURK, Oliver, WOLBOLD, Renzo, HE, You-Qun, KLEIN, Kathrin, NUESSLER, Andreas C, NEUHAUS, Peter, KLATTIG, Jürgen, EISELT, Regina

“…CYP3A proteins comprise a significant portion of the hepatic cytochrome P450 (CYP) protein and they metabolize around 50% of drugs currently in use. The…”
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The Genome of Sulfolobus acidocaldarius, a Model Organism of the Crenarchaeota by Chen, Lanming, Brügger, Kim, Skovgaard, Marie, Redder, Peter, She, Qunxin, Torarinsson, Elfar, Greve, Bo, Awayez, Mariana, Zibat, Arne, Klenk, Hans-Peter, Garrett, Roger A

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification and functional characterization of eight CYP3A4 protein variants by EISELT, Regina, DOMANSKI, Tammy L, KHAN, Kishore K, HE, You-Ai, HALPERT, James R, WOJNOWSKI, Leszek, ZIBAT, Arne, MUELLER, Romy, PRESECAN-SIEDEL, Elena, HUSTERT, Elisabeth, ZANGER, Ulrich M, BROCKMOLLER, Jürgen, KLENK, Hans-Peter, MEYER, Urs A

“…The genetic component of the inter-individual variability in CYP3A4 activity has been estimated to be between 60% and 90%, but the underlying genetic factors…”
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Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles by Lang, Thomas, Klein, Kathrin, Richter, Tanja, Zibat, Arne, Kerb, Reinhold, Eichelbaum, Michel, Schwab, Matthias, Zanger, Ulrich M

“…The human microsomal cytochrome P450, CYP2B6, is involved in the biotransformation of several clinically important drugs. By complete sequence analysis of the…”
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Natural Protein Variants of Pregnane X Receptor with Altered Transactivation Activity Toward CYP3A4 by HUSTERT, Elisabeth, ZIBAT, Arne, BURK, Oliver, PRESECAN-SIEDEL, Elena, EISELT, Regina, MUELLER, Romy, FUSS, Christine, BREHM, Ilka, BRINKMANN, Ulrich, EICHELBAUM, Michel, WOJNOWSKI, Leszek

“…Between 45 and 60% of all drugs currently used are metabolized by the CYP3A4 protein. CYP3A4 expression in liver varies up to 60-fold in the general…”
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Reconstruction of the Central Carbohydrate Metabolism of Thermoproteus tenax by Use of Genomic and Biochemical Data by Siebers, Bettina, Tjaden, Britta, Michalke, Klaus, Dörr, Christine, Ahmed, Hatim, Zaparty, Melanie, Gordon, Paul, Sensen, Christoph W, Zibat, Arne, Klenk, Hans-Peter, Schuster, Stephan C, Hensel, Reinhard

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Characterization of genes from Thermoanaerobacterium thermosulfurigenes EM1 that encode two glycosyl hydrolases with conserved S-layer-like domains by Matuschek, M, Sahm, K, Zibat, A, Bahl, H

“…Two genes from Thermoanaerobacterium thermosulfurigenes EM1 were identified which are predicted to encode a xylanase (XynA) and a polygalacturonate hydrolase…”
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