Search Results - "Zhuravin, I A"
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Neprilysin expression and functions in development, ageing and disease
Published in Mechanisms of ageing and development (01-12-2020)“…•Neprilysin (NEP) participates in development and functions of most body organs•It is an important brain neuropeptidase which cleaves amyloid β (Aβ)…”
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The Alzheimer's Amyloid-Degrading Peptidase, Neprilysin : Can We Control It?
Published in International journal of alzheimer's disease (2012)“…The amyloid cascade hypothesis of Alzheimer's disease (AD) postulates that accumulation in the brain of amyloid β-peptide (Aβ) is the primary trigger for…”
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Early morphological and functional changes in the GABAergic system of hippocampus in the rat lithium-pilocarpine model of epilepsy
Published in Doklady. Biological sciences (2017)“…We studied early alterations in the GABAergic system of the rat hippocampus in the lithium–pilocarpine model of epilepsy. Twenty-four hours after the…”
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Effects of Transient Restraint Stress on the Plasticity of the Cortical Areas of the Brain and Cognitive Functions in Adult Rats with Normal and Disturbed Embryogenesis
Published in Neuroscience and behavioral physiology (01-07-2015)“…The aim of the present work was to analyze changes in the numbers of labile synaptopodin-positive dendritic spines in the parietal cortex and hippocampal field…”
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Electrical activity of the neocortex in adult rats after prenatal hypoxia and in epilepsy model
Published in Journal of evolutionary biochemistry and physiology (01-09-2016)“…Changes in electrical activity of the neocortex after prenatal hypoxia (day 14 of embryogenesis, E14, 7% O 2 for 3 h) and intracortical microinjection of…”
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Ontogenetic Characteristics of Behavior in Rats Subjected to Hypoxia on Day 14 or Day 18 of Embryogenesis
Published in Neuroscience and behavioral physiology (01-02-2010)“…Physiological development, motor activity, and cognitive functions were studied in rats subjected to acute normobaric hypoxic hypoxia (3 h at an O 2…”
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The Ability of NMDA-Type Glutamate Receptor Blockers to Prevent the Development of Pentylenetetrazole Kindling and Morphological Changes to Pyramidal Neurons in the Mouse Hippocampus
Published in Neuroscience and behavioral physiology (01-06-2015)“…Experiments on mice addressed the link between convulsive syndrome and morphological changes in hippocampal neurons occurring on development of…”
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Regulation of Neprilysin Activity and Cognitive Functions in Rats After Prenatal Hypoxia
Published in Neurochemical research (01-06-2019)“…The amyloid-degrading enzyme neprilysin (NEP) is one of the therapeutic targets in prevention and treatment of Alzheimer’s disease (AD). As we have shown…”
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Delayed effect of prenatal exposure to hypoxia on the susceptibility of rats to electric seizures
Published in Doklady. Biological sciences (01-11-2015)“…We studied the delayed effects of prenatal exposure to hypoxia on the susceptibility of rats to seizures. The later was estimated using graded electroshock…”
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Study of distribution of the spine apparatus protein synaptopodin in cortical brain parts of rats exposed to hypoxia at different periods of embryogenesis
Published in Journal of evolutionary biochemistry and physiology (01-10-2010)“…A comparative study of the nervous tissue and distribution of the spine apparatus protein synaptopodin was performed in all layers of the brain sensorimotor…”
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Molecular properties of lysine dendrimers and their interactions with Aβ-peptides and neuronal cells
Published in Current medicinal chemistry (2013)“…Prevention of amyloidosis by chemical compounds is a potential therapeutic strategy in Alzheimer's, prion and other neurodegenerative diseases. Regularly…”
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Effect of Prenatal Hypoxia on Cytoarchitectonics and Ultrustructural Organisation of Brain Regions Related to Olfaction in Rats
Published in Cell and tissue biology (01-09-2021)“…Using light and electron microscopy it was shown that on the 20th day after birth in rats subjected to prenatal hypoxia on day 14 of embryonic development…”
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13
Age-Related ECoG Dynamics of and Convulsive Activity of Wistar Rats in a Cortical Model of Focal Epilepsy
Published in Neuroscience and behavioral physiology (01-10-2018)“…The age-related dynamics of the ECoG and convulsive epileptiform activity induced by intracortical microinjections of 4-aminopyridine were studied in three…”
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Structural changes of the hippocampus nervous tissue in rat ontogenesis after prenatal hypoxia
Published in Journal of evolutionary biochemistry and physiology (01-02-2009)“…It is well known that the main stages of formation of the mammalian brain occurs at the period of embryogenesis and that action of various pathological factors…”
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The Notions of Size and Shape in Old World Monkeys (Macaca mullata): A Comparative Analysis of the Formation Process
Published in Journal of evolutionary biochemistry and physiology (01-05-2018)“…In everyday life, humans and animals occupying different rungs of the “evolutionary ladder” often have to evaluate the notions of larger/smaller size…”
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Changes in Caspase-3 Activity in Early Ontogenesis Lead to Impairments to Memory and Learning in Adult Rats
Published in Neuroscience and behavioral physiology (15-05-2019)“…We report here the first observations of time-delayed degradation of the ability to learn and remember in rats after changes in the level of caspase-3 activity…”
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Changes in the Activity of Amyloid-Degrading Metallopeptidases Leads to Disruption of Memory in Rats
Published in Neuroscience and behavioral physiology (01-11-2010)“…In old male Wistar rats (older than 12 months), or adult males (3–4 months) subjected to prenatal hypoxia (7% O 2 , 3 h, E14), a disruption of short-term…”
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Ultrastructural Alterations in the Sensorimotor Cortex upon Delayed Development of Motor Behavior in Early Ontogenesis of Rats Exposed to Prenatal Hypoxia
Published in Cell and tissue biology (01-09-2018)“…— A comparative study of morphogenesis and synaptogenesis of the sensorimotor cortex and changes in motor behavior during early ontogenesis (Р5, Р14) of rats…”
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Extent of the tetrodotoxin induced blockade examined by pupillary paralysis elicited by intracerebral injection of the drug
Published in Experimental brain research (01-01-1991)“…Spatial extent and duration of the functional blockade elicited by intracerebral injection of tetrodotoxin (TTX) was examined in rats anesthetized with…”
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Localization of the Central Rhythm Generator Involved in Spontaneous Consummatory Licking in Rats: Functional Ablation and Electrical Brain Stimulation Studies
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-1996)“…Localization of the central rhythm generator (CRG) of spontaneous consummatory licking was studied in freely moving rats by microinjection of tetrodotoxin…”
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