Search Results - "Zhukova, L. G."
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The place of CDK4/6 inhibitors in real clinical practice for patients with hormone-positive HER2-negative advanced breast cancer: opinion of Moscow’s oncologists
Published in Opukholi zhenskoĭ reproduktivnoĭ sistemy (09-06-2020)“…The use of CDK4/6 inhibitors in combination with endocrine therapy (aromatase inhibitors and fulvestrant) allowed us to radically change our understanding of…”
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2
Postneoadjuvant therapy: a new approach to the treatment of HER2-positive breast cancer (KATHERINE study results)
Published in Medicinskij sovet (09-12-2019)“…Up until recently, neoadjuvant and adjuvant treatment regimens for breast cancer (BC) were considered equivalent in their effect on long-term treatment…”
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Pharmacoeconomic analysis of using empegfilgrastim for the treatment of early and locally advanced HER2+ breast cancer in the Russian Federation
Published in Farmakoèkonomika (Moskva. Online) (01-02-2024)“…Objective: to assess budget impact of using empegfilgrastim for the prevention of febrile neutropenia in patients with early and locally advanced human…”
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The use of digital radiography in the morphological evaluation of tumor response to neoadjuvant treatment of breast cancer
Published in Arkhiv patologii (2023)“…To optimize the morphological assessment of tumor response to neoadjuvant therapy in breast cancer. A retro- and prospective cohort study was conducted. The…”
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Potential of primary drug prevention of cardiotoxicity in the context of anticancer therapy
Published in Rossiĭskiĭ kardiologicheskiĭ zhurnal (05-01-2023)“…Aim . To search early signs of cardiotoxicity in patients receiving anticancer therapy and evaluate the effectiveness of cardioprotection with an…”
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6
Early and late postoperative complications of robot-assisted radical subcutaneous mastectomy with endoprosthesis
Published in Opukholi zhenskoĭ reproduktivnoĭ sistemy (19-01-2022)“…Over the past two decades, the surgical treatment of breast cancer (BC) has changed from standard radical mastectomies to organ-preserving and reconstructive…”
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7
Multiple primary malignant neoplasms of the mouth and oropharynx
Published in Opukholi golovy i shei (01-08-2022)“…Introduction . Probability of development of multiple primary tumors in patients who received treatment due to head and neck cancers varies between 5.6 and…”
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Olaparib in the metastatic HER2-negative breast cancer setting
Published in Medicinskij sovet (21-12-2020)“…Understanding of cancer biology is at the cornerstone of design of new and effective treatment strategies. Identification of molecular drivers of tumor growth…”
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Target therapy of luminal HER2-negative advanced breast cancer with PIK3CA mutation: combination of alpelisib plus fulvestrant in real clinical practice
Published in Medicinskij sovet (10-12-2021)“…Introduction . Сombination of alpelisib plus fulvestrant is approved in patients with hormone receptor positive, HER2-negative, PIK3CA-mutated advanced breast…”
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Assessment of the receptor status in primary breast cancer with synchronous loco regional metastases: prognostic and clinical role?
Published in Sibirskiĭ onkologicheskiĭ zhurnal (26-04-2019)“…Background. Assessment of hormone receptor status plays a crucial role in treatment of patients with breast cancer. currently, clinicians are limited to…”
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ASSOCIATION OF NKT- AND ACTIVATED CD25+ PERIPHERAL BLOOD LYMPHOCYTES WITH DISEASE FREE AND OVERALL SURVIVAL OF TRIPLE NEGATIVE BREAST CANCER PATIENTS
Published in Sibirskiĭ onkologicheskiĭ zhurnal (31-12-2020)“…Background . We previously found that a decrease in the number of NKT cells and activated CD 25+ peripheral blood lymphocytes (PBLs) before neoadjuvant…”
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The prospects for cisplatin and nab-paclitaxel combination therapy in patients with pre-treated triple-negative breast cancer. Description of the clinical case
Published in Medicinskij sovet (19-07-2018)“…Molecular and biological features of triple negative breast cancer (TN BC) determine the limited possibilities of systemic therapy and, as a consequence, the…”
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Ribociclib in 1st line HR+ breast cancer treatment
Published in Sovremennaia onkologiia : zhurnal kafedry onkologii RMAPO dlia nepreryvnogo poslediplomnogo obrazovaniia (15-06-2018)“…Breast cancer is a leading oncologic disease among women worldwide. Though the achieved results in treating patients with luminal subtypes are high, there is a…”
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Efficacy and safety of cisplatin and paclitaxel (PlaTax regimen) in the neoadjuvant treatment of patients with stage II–III triple-negative breast cancer
Published in Opukholi zhenskoĭ reproduktivnoĭ sistemy (17-11-2020)“…Background . Treatment results for the patients with stage II–III triple negative breast cancer (TN BC) have to be improved. Not only the new treatment…”
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THE MAIN PARAMETERS OF CELLULAR IMMUNITY IN PATIENTS WITH TRIPLE-NEGATIVE BREAST CANCER: RELATIONSHIP WITH EFFICIENCY OF CHEMOTHERAPY
Published in Medit͡s︡inskai͡a︡ immunologii͡a (06-11-2018)“…Chemotherapy is among the primary methods of treating advanced breast cancer. It was shown that clinical efficacy of various chemotherapeutic agents in many…”
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Role of palbociclib in the treatment of hormone receptor-positive HER2-negative metastatic breast cancer. Generalizing results of randomized trials and real clinical practice
Published in Medicinskij sovet (24-06-2019)“…Palbociclib is the first-in-class drug of CDK 4/6 inhibitors group. The use of palbociclib in combination with endocrinotherapy (ET) opens up new possibilities…”
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Optimal duration of adjuvant trastuzumab therapy in patients with HER2-possitive early breast cancer: whether the problem is resolved?
Published in Sovremennaia onkologiia : zhurnal kafedry onkologii RMAPO dlia nepreryvnogo poslediplomnogo obrazovaniia (15-06-2018)“…According to the results of the conducted studies in the early 2000’s, adjuvant trastuzumab for 1 year has been admitted the gold standard since 2006. However,…”
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Russian multicenter experience of using talazoparib in the treatment of patients with BRCA-associated metastatic breast cancer
Published in Medicinskij sovet (21-12-2020)“…Introduction. The presence of a germinal BRCA mutation occurs in 3–4% of all breast cancer (BC) patients with various biological subtypes, but significantly…”
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The use of regorafenib in patients with disseminated gastrointestinal stromal tumours. A review of the literature. A clinical case
Published in Medicinskij sovet (19-07-2018)“…The survival of patients even with disseminated disease reached 7–8 years after introduction of imatinib and sunitinib for the treatment of gastrointestinal…”
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Results of the use of ramucirumab in combination with paclitaxel or ramucirumab monotherapy as the second line treatment in patients with disseminated HER2-negative gastric or cardioesophageal junction adenocarcinoma: experience of N.N. Blokhin russian cancer research center of the ministry of health of Russia
Published in Medicinskij sovet (19-07-2018)“…Background. Working out of the second line chemotherapy of advanced gastric adenocarcinoma is a promising approach to cancer therapy. Ramucirumab, an…”
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