Search Results - "Zhuge, Z."

Blood Pressure–Lowering Effect of Orally Ingested Nitrite Is Abolished by a Proton Pump Inhibitor by Montenegro, Marcelo F, Sundqvist, Michaela L, Larsen, Filip J, Zhuge, Zhengbing, Carlström, Mattias, Weitzberg, Eddie, Lundberg, Jon O

“…Inorganic nitrate and nitrite from dietary and endogenous sources are metabolized to NO and other bioactive nitrogen oxides that affect blood pressure. The…”
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Dietary nitrate attenuates high-fat diet-induced obesity via mechanisms involving higher adipocyte respiration and alterations in inflammatory status by Peleli, M., Ferreira, D.M.S., Tarnawski, L., McCann Haworth, S., Xuechen, L., Zhuge, Z., Newton, P.T., Massart, J., Chagin, A.S., Olofsson, P.S., Ruas, J.L., Weitzberg, E., Lundberg, J.O., Carlström, M.

“…Emerging evidence indicates that dietary nitrate can reverse several features of the metabolic syndrome, but the underlying molecular mechanisms still remain…”
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AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis by Cordero-Herrera, Isabel, Kozyra, Mikael, Zhuge, Zhengbing, Haworth, Sarah McCann, Moretti, Chiara, Peleli, Maria, Caldeira-Dias, Mayara, Jahandideh, Arghavan, Huirong, Han, de Campos Cruz, Josiane, Kleschyov, Andrei L., Montenegro, Marcelo F., Ingelman-Sundberg, Magnus, Weitzberg, Eddie, Lundberg, Jon O., Carlstrom, Mattias

“…Advanced age and unhealthy dietary habits contribute to the increasing incidence of obesity and type 2 diabetes. These metabolic disorders, which are often…”
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Extravasal albumin concentration modulates contractile responses of renal afferent arterioles by Gao, X., Liu, Z. Z., Mohammed, H., Braun, D., Zhuge, Z., Liu, M., Lai, E. Y., Jansson, L., Carlström, M., Patzak, A., Persson, A. E. G.

“…Aim Afferent arterioles (AA) hold a key position in the regulation of renal blood flow and glomerular filtration rate. Being the effector site of…”
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Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell by Sun, Chiao-Wang, Yang, Jiangning, Kleschyov, Andrei L, Zhuge, Zhengbing, Carlström, Mattias, Pernow, John, Wajih, Nadeem, Isbell, T Scott, Oh, Joo-Yeun, Cabrales, Pedro, Tsai, Amy G, Townes, Tim, Kim-Shapiro, Daniel B, Patel, Rakesh P, Lundberg, Jon O

“…BACKGROUND:Nitrosation of a conserved cysteine residue at position 93 in the hemoglobin β chain (β93C) to form S-nitroso (SNO) hemoglobin (Hb) is claimed to be…”
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NO-ferroheme is a signaling entity in the vasculature by Kleschyov, Andrei L., Zhuge, Zhengbing, Schiffer, Tomas A., Guimarães, Drielle D., Zhang, Gensheng, Montenegro, Marcelo F., Tesse, Angela, Weitzberg, Eddie, Carlström, Mattias, Lundberg, Jon O.

“…Despite wide appreciation of the biological role of nitric oxide (NO) synthase (NOS) signaling, questions remain about the chemical nature of NOS-derived…”
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Short communication: Pheromonicin-SA affects mRNA expression of toll-like receptors, cytokines, and lactoferrin by Staphylococcus aureus-infected bovine mammary epithelial cells by Zhu, Y H, Liu, P Q, Weng, X G, Zhuge, Z Y, Zhang, R, Ma, J L, Qiu, X Q, Li, R Q, Zhang, X L, Wang, J F

“…Pheromonicin-SA (Ph-SA) is a newly developed, engineered multidomain peptide that has a bactericidal effect against Staphylococcus aureus. The objective of…”
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Red blood cells from patients with pre-eclampsia induce endothelial dysfunction by McCann Haworth, Sarah M., Zhuge, Zhengbing, Nihlén, Carina, Von Rosen, Matilda Fornell, Weitzberg, Eddie, Lundberg, Jon O., Krmar, Rafael T., Nasiell, Josefine, Carlström, Mattias

“…Pre-eclampsia is a multisystem disorder associated with systemic vascular dysfunction and decreased nitric oxide (NO) bioactivity. Arginase competes with NO…”
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Serum concentration and mRNA expression in milk somatic cells of toll-like receptor 2, toll-like receptor 4, and cytokines in dairy cows following intramammary inoculation with Escherichia coli by Ma, J L, Zhu, Y H, Zhang, L, Zhuge, Z Y, Liu, P Q, Yan, X D, Gao, H S, Wang, J F

“…The objective of the current study was to investigate the toll-like receptors (TLR), including the soluble forms sTLR2 and sTLR4, involved in innate immune…”
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Cholinergic regulation of vascular endothelial function by human ChAT + T cells by Tarnawski, Laura, Shavva, Vladimir S, Kort, Eric J, Zhuge, Zhengbing, Nilsson, Ingrid, Gallina, Alessandro L, Martínez-Enguita, David, Heller Sahlgren, Benjamin, Weiland, Matthew, Caravaca, April S, Schmidt, Staffan, Chen, Ping, Abbas, Katarina, Wang, Fu-Hua, Ahmed, Osman, Eberhardson, Michael, Färnert, Anna, Weitzberg, Eddie, Gustafsson, Mika, Kehr, Jan, Malin, Stephen G, Hult, Henrik, Carlström, Mattias, Jovinge, Stefan, Olofsson, Peder S

“…Endothelial dysfunction and impaired vasodilation are linked with adverse cardiovascular events. T lymphocytes expressing choline acetyltransferase (ChAT), the…”
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The obligatory role of host microbiota in bioactivation of dietary nitrate by Moretti, Chiara, Zhuge, Zhengbing, Zhang, Gensheng, Haworth, Sarah McCann, Paulo, Luciano L., Guimarães, Drielle D., Cruz, Josiane C., Montenegro, Marcelo F., Cordero-Herrera, Isabel, Braga, Valdir A., Weitzberg, Eddie, Carlström, Mattias, Lundberg, Jon O.

“…Nitric oxide (NO) is a key signalling molecule in the regulation of cardiometabolic function and impaired bioactivity is considered to play an important role…”
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Dietary Nitrate Reduces Blood Pressure in Rats With Angiotensin II–Induced Hypertension via Mechanisms That Involve Reduction of Sympathetic Hyperactivity by Guimarães, Drielle D, Cruz, Josiane C, Carvalho-Galvão, Alynne, Zhuge, Zhengbing, Marques, Stefanne M, Naves, Lara M, Persson, A. Erik G, Weitzberg, Eddie, Lundberg, Jon O, Balarini, Camille M, Pedrino, Gustavo R, Braga, Valdir A, Carlström, Mattias

“…Several experimental and clinical studies have shown that dietary nitrate supplementation can increase nitric oxide bioavailability. In the oral cavity,…”
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Synthesis and characterization of a novel organic nitrate NDHP: Role of xanthine oxidoreductase-mediated nitric oxide formation by Zhuge, Zhengbing, Paulo, Luciano L., Jahandideh, Arghavan, Brandão, Maria C.R., Athayde-Filho, Petrônio F., Lundberg, Jon O., Braga, Valdir A., Carlström, Mattias, Montenegro, Marcelo F.

“…In this report, we describe the synthesis and characterization of 1,3-bis(hexyloxy)propan-2-yl nitrate (NDHP), a novel organic mono nitrate. Using purified…”
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Protective effects of S-adenosylmethionine against CCl4- and ethanol-induced experimental hepatic fibrosis by Zhang, F., Gu, J.-X., Zou, X.-P., Zhuge, Y.-Z.

“…In this study the effects of S-adenosylmethionine (SAM) on experimental hepatic fibrotic rats induced by carbon tetrachloride (CCl 4 ) and ethanol and the…”
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Head-to-head comparison of inorganic nitrate and metformin in a mouse model of cardiometabolic disease by Cordero-Herrera, Isabel, Guimarães, Drielle D., Moretti, Chiara, Zhuge, Zhengbing, Han, Huirong, McCann Haworth, Sarah, Uribe Gonzalez, Arturo Eduardo, Andersson, Daniel C., Weitzberg, Eddie, Lundberg, Jon O., Carlström, Mattias

“…Unhealthy dietary habits contribute to the increasing incidence of metabolic syndrome and type 2 diabetes (T2D), which is accompanied by oxidative stress,…”
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Red blood cells from endothelial nitric oxide synthase-deficient mice induce vascular dysfunction involving oxidative stress and endothelial arginase I by Zhuge, Zhengbing, McCann Haworth, Sarah, Nihlén, Carina, Carvalho, Lucas Rannier R.A., Heuser, Sophia K., Kleschyov, Andrei L., Nasiell, Josefine, Cortese-Krott, Miriam M., Weitzberg, Eddie, Lundberg, Jon O., Carlström, Mattias

“…Nitric oxide bioactivity (NO) from endothelial NO synthase (eNOS) importantly contributes to the maintenance of vascular homeostasis, and reduced eNOS activity…”
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Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress by Yang, Ting, Zhang, Xing-Mei, Tarnawski, Laura, Peleli, Maria, Zhuge, Zhengbing, Terrando, Niccolo, Harris, Robert A., Olofsson, Peder S., Larsson, Erik, Persson, A. Erik G., Lundberg, Jon O., Weitzberg, Eddie, Carlstrom, Mattias

“…Ischemia-reperfusion (IR) injury involves complex pathological processes in which reduction of nitric oxide (NO) bioavailability is suggested as a key factor…”
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Downregulation of eNOS and preserved endothelial function in endothelial-specific arginase 1-deficient mice by Heuser, Sophia K., LoBue, Anthea, Li, Junjie, Zhuge, Zhengbing, Leo, Francesca, Suvorava, Tatsiana, Olsson, Annika, Schneckmann, Rebekka, Guimaraes Braga, Drielle D., Srivrastava, Tanu, Montero, Lidia, Schmitz, Oliver J., Schmitt, Joachim P., Grandoch, Maria, Weitzberg, Eddie, Lundberg, Jon O., Pernow, John, Kelm, Malte, Carlström, Mattias, Cortese-Krott, Miriam M.

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Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway by Li, Xuechen, Zhuge, Zhengbing, Carvalho, Lucas Rannier R.A., Braga, Valdir A., Lucena, Ricardo Barbosa, Li, Shuijie, Schiffer, Tomas A., Han, Huirong, Weitzberg, Eddie, Lundberg, Jon O., Carlström, Mattias

“…Renal fibrosis, associated with oxidative stress and nitric oxide (NO) deficiency, contributes to the development of chronic kidney disease and renal failure…”
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Cardiovascular characterization of the novel organic mononitrate NDIBP in rats by Cavalcanti, Airlla Laana de Medeiros, Rocha, Patrícia Keytth Lins, Zhuge, Zhengbing, Montenegro, Marcelo F., Paulo, Luciano Leite, Mendes-Júnior, Leônidas das Graças, Brandão, Maria Cláudia Rodrigues, Athayde-Filho, Petrônio F., Lundberg, Jon O., Weitzberg, Eddie, Carlström, Mattias, Braga, Valdir de Andrade

“…Organic nitrates are widely used to restore endogenous nitric oxide (NO) levels reduced by endothelial nitric oxide synthase dysfunction. However, these drugs…”
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