Search Results - "Zhubi, A"

Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons by Satta, R, Maloku, E, Zhubi, A, Pibiri, F, Hajos, M, Costa, E, Guidotti, A

“…Tobacco smoking is frequently abused by schizophrenia patients (SZP). The major synaptically active component inhaled from cigarettes is nicotine, hence the…”
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Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum by Zhubi, A, Chen, Y, Dong, E, Cook, E H, Guidotti, A, Grayson, D R

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by symptoms related to altered social interactions/communication and restricted…”
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Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection by RUZICKA, W. B, ZHUBI, A, VELDIC, M, GRAYSON, D. R, COSTA, E, GUIDOTTI, A

“…Among the most consistent results of studies of post-mortem brain tissue from schizophrenia patients (SZP) is the finding that in this disease, several genes…”
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An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes by Zhubi, A, Veldic, M, Puri, N.V, Kadriu, B, Caruncho, H, Loza, I, Sershen, H, Lajtha, A, Smith, R.C, Guidotti, A, Davis, J.M, Costa, E

“…Abstract Several lines of schizophrenia (SZ) research suggest that a functional downregulation of the prefrontal cortex GABAergic neuronal system is mediated…”
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Toward the Identification of Peripheral Epigenetic Biomarkers of Schizophrenia by Guidotti, A., Auta, J., Davis, J. M., Dong, E., Gavin, D. P., Grayson, D. R., Sharma, R. P., Smith, R. C., Tueting, P., Zhubi, A.

“…Abstract Schizophrenia (SZ) is a heritable, nonmendelian, neurodevelopmental disorder in which epigenetic dysregulation of the brain genome plays a fundamental…”
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Nicotinic cholinergic mechanisms in the regulation of brain DNA-methyltransferase 1 (DNMT1) expression by Maloku, E, Satta, R, Zhubi, A, Veldic, M, Kadriu, B, Guidotti, A, Costa, E

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Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects by Zhubi, Adrian, Chen, Ying, Guidotti, Alessandro, Grayson, Dennis R.

“…•The RELN and GAD1 mRNA levels were reduced in ASD PFC.•TET 1, 2, and 3 mRNAs were increased in ASD PFC.•There was increased DNMT1 and MECP2 promoter…”
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Imidazenil and Diazepam Increase Locomotor Activity in Mice Exposed to Protracted Social Isolation by Pinna, Graziano, Agis-Balboa, Roberto C., Zhubi, Adrian, Matsumoto, Kinzo, Grayson, Dennis R., Costa, Erminio, Guidotti, Alessandro

“…In cortex and hippocampus, protracted (>4 weeks) social isolation of adult male mice alters the subunit expression of GABA type A receptors ($GABA_{A}-RS$) as…”
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