Search Results - "Zhuang, Xianghua"
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Exploring new mechanisms of Imeglimin in diabetes treatment: Amelioration of mitochondrial dysfunction
Published in Biomedicine & pharmacotherapy (01-06-2024)“…With the increasing prevalence of type 2 diabetes mellitus (T2DM), it has become critical to identify effective treatment strategies. In recent years, the…”
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Lipin1 Alleviates Autophagy Disorder in Sciatic Nerve and Improves Diabetic Peripheral Neuropathy
Published in Molecular neurobiology (01-11-2021)“…Diabetic peripheral neuropathy (DPN) is a chronic complication of diabetes, and its neural mechanisms underlying the pathogenesis remain unclear. Autophagy…”
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Changes in the central nervous system in diabetic neuropathy
Published in Heliyon (01-08-2023)“…One of the most common chronic complications arising from diabetes is diabetic peripheral neuropathy. Depending on research statistics, approximately half of…”
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Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway
Published in Lipids in health and disease (09-12-2016)“…Obesity is closely related to the metabolism of triacylglycerol (TG) in adipocytes. Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) are…”
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Corrigendum: Correlation of mild cognitive impairment with the thickness of retinal nerve fiber layer and serum indicators in type 2 diabetic patients
Published in Frontiers in endocrinology (Lausanne) (25-04-2024)“…[This corrects the article DOI: 10.3389/fendo.2023.1299206.]…”
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Correlation of mild cognitive impairment with the thickness of retinal nerve fiber layer and serum indicators in type 2 diabetic patients
Published in Frontiers in endocrinology (Lausanne) (08-01-2024)“…Cognitive Impairment arising from type 2 diabetes mellitus (T2DM) has garnered significant attention in recent times. However, there are few studies on the…”
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Phosphatidate phosphatase Lipin1 involves in diabetic encephalopathy pathogenesis via regulating synaptic mitochondrial dynamics
Published in Redox biology (01-02-2024)“…Diabetic encephalopathy (DE) is a common central nervous system complication of diabetes mellitus without effective therapy currently. Recent studies have…”
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Baseline characteristics and changes of biomarkers in disease course predict prognosis of patients with COVID-19
Published in Internal and emergency medicine (01-08-2021)“…The outbreak of coronavirus disease (COVID-19) has brought great challenges to the world. The objectives of this study were to describe the baseline…”
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Efficacy and safety of umbilical cord mesenchymal stem cells for the treatment of patients with COVID-19
Published in Clinics (São Paulo, Brazil) (01-01-2021)“…The coronavirus disease (COVID-19) outbreak has catastrophically threatened public health worldwide and presented great challenges for clinicians. To date, no…”
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Abnormal liver-related biomarkers in COVID-19 patients and the role of prealbumin
Published in Saudi journal of gastroenterology (01-09-2020)“…Background/Aims: We aimed to evaluate the distribution of abnormal liver-related biomarkers in patients with coronavirus disease (COVID-19) and explore the…”
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Correlation between lower extremity arterial disease and skeletal muscle mass in patients with type 2 diabetes mellitus
Published in Journal of international medical research (01-03-2020)“…Objectives To evaluate skeletal muscle mass in patients with both type 2 diabetes mellitus (T2DM) and concomitant lower extremity arterial disease (LEAD) and…”
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Therapeutic Effect of Metformin on Chemerin in Non-Obese Patients with Non-Alcoholic Fatty Liver Disease (NAFLD)
Published in Clinical laboratory (Heidelberg) (2015)“…Chemerin is an important risk factor of insulin resistance. Non-alcoholic fatty liver has typical characteristics of insulin resistance. The aim of this study…”
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Research Progress on Lipocalin-2 in Diabetic Encephalopathy
Published in Neuroscience (01-04-2023)“…[Display omitted] •Type 2 Diabetes Mellitus increases the risk of dementia.•Lipocalin-2 levels may change with the progression of diabetes.•Lipocalin-2 is…”
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488-P: Phosphatidate Phosphatase Lipin1 Is Involved in the Development of Diabetic Encephalopathy by Regulating the Homeostasis of Mitochondria-Associated Endoplasmic Reticulum (MAMs)
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Introduction & Objective: Diabetic encephalopathy (DE) is a common chronic central nervous system complication without clear elucidation of pathogenesis as…”
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The level of serum retinol-binding protein is associated with diabetic mild cognitive impairment
Published in Brain research (01-01-2024)“…Several studies have shown that retinol-binding protein (RBP) is linked to diabetes and neurodegenerative diseases. However, no studies have elucidated the…”
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Lipin1 mediates cognitive impairment in fld mice via PKD-ERK pathway
Published in Biochemical and biophysical research communications (30-04-2020)“…Lipin1 is important in lipid synthesis because of its phosphatidate phosphatase activity, and it also functions as transcriptional coactivators to regulate the…”
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Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation
Published in International immunopharmacology (01-05-2023)“…[Display omitted] •Lipin2 improves cytotoxicity and inflammation induced by high glucose in BV2 cells.•Lipin2 expression was down-regulated in hippocampus of…”
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Effectiveness Evaluation of a Primary School-Based Intervention against Heatwaves in China
Published in International journal of environmental research and public health (22-02-2022)“…Evidence of the effectiveness of intervention against extreme heat remains unclear, especially among children, one of the vulnerable populations. This study…”
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