Search Results - "Zhu Qiong"
-
1
Isolation and characterization of exosomes for cancer research
Published in Journal of hematology and oncology (10-11-2020)“…Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins, nucleic acids, metabolites, and lipids. Mounting evidence…”
Get full text
Journal Article -
2
MFN1-dependent alteration of mitochondrial dynamics drives hepatocellular carcinoma metastasis by glucose metabolic reprogramming
Published in British journal of cancer (01-01-2020)“…Background Mitochondrial dynamics plays an important role in tumour progression. However, how these dynamics integrate tumour metabolism in hepatocellular…”
Get full text
Journal Article -
3
Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade
Published in Gut (01-09-2019)“…In the tumour microenvironment, critical drivers of immune escape include the oncogenic activity of the tumour cell-intrinsic osteopontin (OPN), the expression…”
Get more information
Journal Article -
4
Characteristics of the cancer stem cell niche and therapeutic strategies
Published in Stem cell research & therapy (03-06-2022)“…Distinct regions harboring cancer stem cells (CSCs) have been identified within the microenvironment of various tumors, and as in the case of their healthy…”
Get full text
Journal Article -
5
The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives
Published in Signal transduction and targeted therapy (05-07-2021)“…Pancreatic cancer is an increasingly common cause of cancer mortality with a tight correspondence between disease mortality and incidence. Furthermore, it is…”
Get full text
Journal Article -
6
MicroRNA‐26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin‐6‐Stat3 pathway
Published in Hepatology (Baltimore, Md.) (01-07-2013)“…Down‐regulation of microRNA‐26a (miR‐26a) is associated with poor prognosis of hepatocellular carcinoma (HCC), but its functional mechanism in HCC remains…”
Get full text
Journal Article -
7
MicroRNA‐26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor‐cMet pathway
Published in Hepatology (Baltimore, Md.) (01-05-2014)“…MicroRNA (miR)‐26a can suppress tumor growth and metastasis of hepatocellular carcinoma (HCC). Since angiogenesis is important for tumor growth and metastasis,…”
Get full text
Journal Article -
8
Prospero‐related homeobox 1 drives angiogenesis of hepatocellular carcinoma through selectively activating interleukin‐8 expression
Published in Hepatology (Baltimore, Md.) (01-12-2017)“…Angiogenesis has been proven to play an important role in the progression of hepatocellular carcinoma (HCC). However, the molecular mechanism underlying HCC…”
Get full text
Journal Article -
9
FOXQ1/NDRG1 axis exacerbates hepatocellular carcinoma initiation via enhancing crosstalk between fibroblasts and tumor cells
Published in Cancer letters (28-03-2018)“…Cancer associated fibroblast (CAF) is a well-known microenvironment contributor for the development of hepatocellular carcinoma (HCC), while forkhead box (FOX)…”
Get full text
Journal Article -
10
MALAT1: a potential biomarker in cancer
Published in Cancer management and research (01-01-2018)“…The research of long non-coding RNAs (lncRNAs) has become a new passion with the discovery of abundant new lncRNAs and extensive investigation of their roles…”
Get full text
Journal Article -
11
C‐C chemokine receptor type 1 mediates osteopontin‐promoted metastasis in hepatocellular carcinoma
Published in Cancer science (01-03-2018)“…In the hepatocellular carcinoma (HCC) microenvironment, chemokine receptors play a critical role in tumorigenesis and metastasis. Our previous studies have…”
Get full text
Journal Article -
12
Current perspectives of cancer-associated fibroblast in therapeutic resistance: potential mechanism and future strategy
Published in Cell biology and toxicology (01-10-2019)“…The goal of cancer eradication has been overshadowed despite the continuous improvement in research and generation of novel cancer therapeutic drugs. One of…”
Get full text
Journal Article -
13
Therapeutic Strategies Targeting Cancer Stem Cells and Their Microenvironment
Published in Frontiers in oncology (24-10-2019)“…Cancer stem cells (CSCs) have been demonstrated in a variety of tumors and are thought to act as a clonogenic core for the genesis of new tumor growth. This…”
Get full text
Journal Article -
14
Early growth response‐1 regulates acetylcholinesterase and its relation with the course of Alzheimer’s disease
Published in Brain pathology (Zurich, Switzerland) (01-07-2019)“…Our previous studies showed that the transcription factor early growth response‐1 (EGR1) may play a role in keeping the brain cholinergic function intact in…”
Get full text
Journal Article -
15
Green tea polyphenols ameliorate non-alcoholic fatty liver disease through upregulating AMPK activation in high fat fed Zucker fatty rats
Published in World journal of gastroenterology : WJG (07-06-2017)“…AIM To investigate protective effects and molecular mechanisms of green tea polyphenols(GTP) on nonalcoholic fatty liver disease(NAFLD) in Zucker fatty(ZF)…”
Get full text
Journal Article -
16
Genomic aberrations in the HTPAP promoter affect tumor metastasis and clinical prognosis of hepatocellular carcinoma
Published in PloS one (06-03-2014)“…We previously reported that the intronic tagSNP +357G/C in the metastasis suppressor HTPAP is associated with metastasis and prognosis of hepatocellular…”
Get full text
Journal Article -
17
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis
Published in Nature communications (02-07-2019)“…The deubiquitylase OTUD3 plays a suppressive role in breast tumorigenesis through stabilizing PTEN protein, but its role in lung cancer remains unclear. Here,…”
Get full text
Journal Article -
18
Human mesenchymal stem cells inhibit metastasis of a hepatocellular carcinoma model using the MHCC97‐H cell line
Published in Cancer science (01-12-2010)“…The effects of mesenchymal stem cells (MSC) on the growth and metastasis of human malignancies including hepatocellular carcinoma (HCC) are controversial, and…”
Get full text
Journal Article -
19
PKM2 Drives Hepatocellular Carcinoma Progression by Inducing Immunosuppressive Microenvironment
Published in Frontiers in immunology (20-10-2020)“…Pyruvate kinase M2 (PKM2) is an essential regulator of the Warburg effect, but its biological function promoting immune escape of hepatocellular carcinoma…”
Get full text
Journal Article -
20
Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity
Published in Biochimica et biophysica acta. Molecular basis of disease (01-06-2018)“…Primary liver cancer (PLC) is the third largest contributor to cancer mortality in the world. PLC is a heterogeneous disease that encompasses several…”
Get full text
Journal Article